Paper Review Records
All Paper Review Records
10 valid samples · Newest publication first
Review days = acceptance date − received date. PDF, DOI, and publisher-page sources are retained.
Pharmacokinetics of repeated, high-dose fentanyl administration in rats
AuthorsDavid P. Obert; Autumn McKnite; Gwi H. Park; Kevin M. Watt; Christopher A. Reilly; Kathleen F. Vincent; Joseph E. Rower; Ken Solt
AffiliationsDepartment of Anesthesiology and Intensive Care Medicine, School of Medicine and Health, Technical University of Munich, Munich, Germany; Department of Anesthesiology, Mass General Brigham, Boston, Massachusetts; Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts; Division of Clinical Pharmacology, Department of Pediatrics, University of Utah, Salt Lake City, Utah; Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, Salt Lake City, Utah
Effects of simulated exogenous and endogenous lipid microenvironments on cannabidiol disposition and cytochrome P450 2C19–mediated drug interactions: New mechanistic insights
AuthorsAiden-Hung P. Nguyen; Fridah C. Rotich; Nadja B. Cech; Mary F. Paine
AffiliationsDepartment of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina; Center of Excellence for Natural Product Drug Interaction Research, Spokane, Washington
Cell line–dependent metabolic fate of curcumin analogs assessed by liquid chromatography with quadrupole time-of-flight mass spectrometry and subcellular microscopy
AuthorsJulie De Munck; Yannick Verheust; Charlotte Grootaert; Maximiliaan De Wolf; Katarina Magdalenic; Katleen Raes; Matthias D’hooghe; John Van Camp
AffiliationsLaboratory of Food Chemistry and Human Nutrition, Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium; Research Unit VEG-i-TEC, Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Kortrijk, Belgium; SynBioC Research Group, Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium
Modeling cortisol and cortisone binding to corticosteroid-binding globulin and albumin based on clinical protein binding data
AuthorsAurora K. Authement; Abhinav Nath; Katya B. Rubinow; John K. Amory; Nina Isoherranen
AffiliationsDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington; Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, Seattle, Washington; Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington
A 3-step static mechanistic modeling approach to predicting transporter- and enzyme-mediated interaction signals of direct oral anticoagulants
AuthorsMostafa ben Ahmed; Anne M. Filppula; Aleksi Tornio
AffiliationsIntegrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland; Unit of Clinical Pharmacology, Turku University Hospital, Turku, Finland; Pharmaceutical Sciences Laboratory, Department of Natural and Health Sciences, Faculty of Science and Engineering, Åbo Akademi University, Turku, Finland
Generation and characterization of a serum albumin-humanized mouse model and its utility for detection of albumin adduct formation in vivo
AuthorsXiangmeng Wu; Weiguo Han; Lei Yin; Weizhu Yang; Jonathan Sheng; John Han; Robert J. Turesky; Laura S. Van Winkle; Qing-Yu Zhang; Xinxin Ding
AffiliationsDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona; School of Pharmacy, American University of Health Sciences, Signal Hill, California; Masonic Cancer Center and Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota; Center for Health and the Environment and Department of Anatomy Physiology and Cell Biology, School of Veterinary Medicine, UC Davis, Davis, California
Mechanistically resolved prediction of compound hepatotoxicity using primary human liver spheroids—Application to recent real-world cases
AuthorsYufeng Li; Hongda Sheng; Tingting Zhou; Chen Xing; Miriam Kukasch; Siyuan Shao; Sonia Youhanna; Sabine U. Vorrink; Yingxin Liang; Anne T. Nies; Julia Dressler; Charlotte Kölz; Jinhye Ryu; Nayere Taebnia; Dominik Jacob; Caroline Hauser; Carl Petersson; Kathrin Klein; Oliver Burk; Boxu Shi; Qiaojun He; Volker M. Lauschke
AffiliationsCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China; National Key Laboratory of Chinese Medicine Modernization, Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing, China; Shanghai Hepo Biotechnology Co, Ltd, Shanghai, China; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tübingen, Tübingen, Germany; Department of Physiology and Pharmacology and Center for Molecular Medicine, Karolinska Institutet and University Hospital, Stockholm, Sweden; HepaPredict AB, Stockholm, Sweden; Department of Drug Metabolism and Pharmacokinetics (DMPK), the Healthcare Business of Merck KGaA, Darmstadt, Germany; The Chinese University of Hong Kong, Shenzhen, China; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China
Investigation of biomarkers for azole antifungal-induced liver injury using primary human hepatocyte spheroids
AuthorsMasaki Kumondai; Ayaka Yagi; Masahiro Watanabe; Yanlin Lyu; Ryosuke Segawa; Mayumi Sato; Ryo Tadakuma; Kenji Inoue; Hideki Watanabe; Masahiro Takeda; Yoshiteru Ohshima; Masamitsu Maekawa; Nariyasu Mano
AffiliationsDepartment of Pharmaceutical Sciences, Tohoku University Hospital, Aoba-ku, Sendai, Japan; Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Japan; Drug Development Research Laboratories, Kyoto R&D Center, Maruho Co, Ltd, Kita-ku, Osaka, Japan; Head Office for Open Innovation Business Development Strategy, Tohoku University, Aoba-ku, Sendai, Japan
Absorption, metabolism, and excretion of single dose oral [14C]camizestrant in healthy human female participants
AuthorsAndy Sykes; Zhoupeng Zhang; Jana Skeete; Pradeep Sharma; Stephen Wilkinson; Ryan Bragg; Sasha McClain; Malin Gränfors; Isobel Leddin; Christopher Bailey; Bistra Kirova; Nand Singh; Karthick Vishwanathan; Niresh Hariparsad
AffiliationsClinical Pharmacology and Quantitative Pharmacology, AstraZeneca, Cambridge, UK; Drug Metabolism and Pharmacokinetics, Oncology R&D, AstraZeneca, Waltham, Massachusetts; Drug Metabolism and Pharmacokinetics, Oncology R&D, AstraZeneca, Cambridge, UK; Early Chemical Development, Pharmaceutical Sciences, AstraZeneca, Cambridge, UK; Late Development, Oncology R&D, AstraZeneca, Gaithersburg, Maryland; Early Product Development and Manufacturing, Pharmaceutical Sciences, AstraZeneca, Gothenburg, Sweden; Late Development, Oncology R&D, AstraZeneca, Cambridge, UK; Integrated Bioanalysis, AstraZeneca, Cambridge, UK; Oncology Patient Safety, Oncology R&D, AstraZeneca, Cambridge, UK; Medical Department, Quotient Sciences, Ruddington, Nottingham, UK; Clinical Pharmacology and Pharmacometrics, AstraZeneca, Waltham, Massachusetts
Reduction of secondary 3-keto bile acids by aldo-keto reductase 1C1 and 1C4
AuthorsKeith D. Green; Graham K. Thomason; Lindsay C. Czuba
AffiliationsDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky
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