DRUG METABOLISM AND DISPOSITION

作者David P. Obert; Autumn McKnite; Gwi H. Park; Kevin M. Watt; Christopher A. Reilly; Kathleen F. Vincent; Joseph E. Rower; Ken Solt

作者单位Department of Anesthesiology and Intensive Care Medicine, School of Medicine and Health, Technical University of Munich, Munich, Germany; Department of Anesthesiology, Mass General Brigham, Boston, Massachusetts; Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts; Division of Clinical Pharmacology, Department of Pediatrics, University of Utah, Salt Lake City, Utah; Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, Salt Lake City, Utah

作者Aiden-Hung P. Nguyen; Fridah C. Rotich; Nadja B. Cech; Mary F. Paine

作者单位Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington; Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina; Center of Excellence for Natural Product Drug Interaction Research, Spokane, Washington

作者Julie De Munck; Yannick Verheust; Charlotte Grootaert; Maximiliaan De Wolf; Katarina Magdalenic; Katleen Raes; Matthias D’hooghe; John Van Camp

作者单位Laboratory of Food Chemistry and Human Nutrition, Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium; Research Unit VEG-i-TEC, Department of Food Technology, Safety and Health, Faculty of Bioscience Engineering, Ghent University, Kortrijk, Belgium; SynBioC Research Group, Department of Green Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium

作者Aurora K. Authement; Abhinav Nath; Katya B. Rubinow; John K. Amory; Nina Isoherranen

作者单位Department of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, Washington; Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, Seattle, Washington; Division of Internal Medicine, Department of Medicine, University of Washington, Seattle, Washington

作者Mostafa ben Ahmed; Anne M. Filppula; Aleksi Tornio

作者单位Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland; Unit of Clinical Pharmacology, Turku University Hospital, Turku, Finland; Pharmaceutical Sciences Laboratory, Department of Natural and Health Sciences, Faculty of Science and Engineering, Åbo Akademi University, Turku, Finland

作者Xiangmeng Wu; Weiguo Han; Lei Yin; Weizhu Yang; Jonathan Sheng; John Han; Robert J. Turesky; Laura S. Van Winkle; Qing-Yu Zhang; Xinxin Ding

作者单位Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona; School of Pharmacy, American University of Health Sciences, Signal Hill, California; Masonic Cancer Center and Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota; Center for Health and the Environment and Department of Anatomy Physiology and Cell Biology, School of Veterinary Medicine, UC Davis, Davis, California

作者Yufeng Li; Hongda Sheng; Tingting Zhou; Chen Xing; Miriam Kukasch; Siyuan Shao; Sonia Youhanna; Sabine U. Vorrink; Yingxin Liang; Anne T. Nies; Julia Dressler; Charlotte Kölz; Jinhye Ryu; Nayere Taebnia; Dominik Jacob; Caroline Hauser; Carl Petersson; Kathrin Klein; Oliver Burk; Boxu Shi; Qiaojun He; Volker M. Lauschke

作者单位College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China; National Key Laboratory of Chinese Medicine Modernization, Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing, China; Shanghai Hepo Biotechnology Co, Ltd, Shanghai, China; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tübingen, Tübingen, Germany; Department of Physiology and Pharmacology and Center for Molecular Medicine, Karolinska Institutet and University Hospital, Stockholm, Sweden; HepaPredict AB, Stockholm, Sweden; Department of Drug Metabolism and Pharmacokinetics (DMPK), the Healthcare Business of Merck KGaA, Darmstadt, Germany; The Chinese University of Hong Kong, Shenzhen, China; Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, China

作者Masaki Kumondai; Ayaka Yagi; Masahiro Watanabe; Yanlin Lyu; Ryosuke Segawa; Mayumi Sato; Ryo Tadakuma; Kenji Inoue; Hideki Watanabe; Masahiro Takeda; Yoshiteru Ohshima; Masamitsu Maekawa; Nariyasu Mano

作者单位Department of Pharmaceutical Sciences, Tohoku University Hospital, Aoba-ku, Sendai, Japan; Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Japan; Drug Development Research Laboratories, Kyoto R&D Center, Maruho Co, Ltd, Kita-ku, Osaka, Japan; Head Office for Open Innovation Business Development Strategy, Tohoku University, Aoba-ku, Sendai, Japan

作者Andy Sykes; Zhoupeng Zhang; Jana Skeete; Pradeep Sharma; Stephen Wilkinson; Ryan Bragg; Sasha McClain; Malin Gränfors; Isobel Leddin; Christopher Bailey; Bistra Kirova; Nand Singh; Karthick Vishwanathan; Niresh Hariparsad

作者单位Clinical Pharmacology and Quantitative Pharmacology, AstraZeneca, Cambridge, UK; Drug Metabolism and Pharmacokinetics, Oncology R&D, AstraZeneca, Waltham, Massachusetts; Drug Metabolism and Pharmacokinetics, Oncology R&D, AstraZeneca, Cambridge, UK; Early Chemical Development, Pharmaceutical Sciences, AstraZeneca, Cambridge, UK; Late Development, Oncology R&D, AstraZeneca, Gaithersburg, Maryland; Early Product Development and Manufacturing, Pharmaceutical Sciences, AstraZeneca, Gothenburg, Sweden; Late Development, Oncology R&D, AstraZeneca, Cambridge, UK; Integrated Bioanalysis, AstraZeneca, Cambridge, UK; Oncology Patient Safety, Oncology R&D, AstraZeneca, Cambridge, UK; Medical Department, Quotient Sciences, Ruddington, Nottingham, UK; Clinical Pharmacology and Pharmacometrics, AstraZeneca, Waltham, Massachusetts

作者Keith D. Green; Graham K. Thomason; Lindsay C. Czuba

作者单位Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky