Paper Review Records
All Paper Review Records
10 valid samples · Newest publication first
Review days = acceptance date − received date. PDF, DOI, and publisher-page sources are retained.
Functional mapping of the Trypanosoma cruzi serinome by fluorophosphonate activity-based protein profiling
AuthorsJaime A. Isern; María Gabriela Mediavilla; Exequiel O.J. Porta; Marcelo L. Merli; María Sol Ballari; Julia A. Cricco; Guillermo R. Labadie; Patrick G. Steel
AffiliationsDepartment of Chemistry, Durham University, Stockton Rd, DH1 3LE Durham, United Kingdom; Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET-UNR), Ocampo y Esmeralda, Rosario 2000, Argentina; Instituto de Química Rosario (IQUIR-CONICET-UNR), Universidad Nacional de Rosario, Argentina; Departamento de Química Orgánica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Argentina
Design, synthesis, and biological evaluation of novel phenylindole derivatives as P-gp inhibitors to overcome multidrug resistance in MCF-7/ADR cells
AuthorsZhikun Yang; Yingjia Ding; Keren Xu; Jiajia Han; Junzhe Hu; Sherien M. Bakry; Yi Hua; Hong Wang
AffiliationsCollege of Pharmaceutical Science & Jianxing Honors College, Zhejiang University of Technology, Hangzhou 310014, China; Zhejiang Key Laboratory of Green Manufacturing Technology for Chemical Drugs, Hangzhou 310014, China; Zhejiang-Egypt Joint Laboratory on Intelligent Discovery of Marine Drugs, Hangzhou 310014, China; Phytochemistry and Plant Systematics Department, National Research Centre, 33 El Bohouth St. Dokki, Giza 12622, Egypt
Discovery of SARS-CoV-2 PLpro covalent inhibitors enabled by a novel reversible covalent chloroalkyne warhead
AuthorsDivakar Indukuri; Jazmin Galván Achi; Boopathi Sownthirarajan; Malla Reddy Gannarapu; Omar Lozano Ramos; Kiira Ratia; Priyajit Kaur; Rishi Vardhan Chunduru; Zuohuang Qi; Paulina Anguiano; Balaji Manicassamy; Lijun Rong; Rui Xiong
AffiliationsDepartment of Pharmacology & Toxicology, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ, USA; Department of Microbiology and Immunology, College of Medicine, University of Illinois Chicago (UIC), Chicago, IL, USA; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Research Resources Center, University of Illinois Chicago (UIC), Chicago, IL, USA; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.
Design, synthesis, antitumor estimation, and molecular docking of new imidazothiazolediones as potential dual EGFR and IDO1 inhibitors and apoptosis stimulators
AuthorsMarwa T. Sarg; Fatma G. Abdulrahman; Yasmin S. Sheta; Eman S. Nossier; Ebtehal M. Husseiny
AffiliationsPharmaceutical Organic Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Nasr City 11754, Cairo, Egypt; Department of Chemistry, Faculty of Pharmacy, Ahram Canadian University, 6th-October, Giza, Egypt; Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11754, Egypt
Evaluating the outputs of ARAE-based molecular generative model for synthetic accessibility and BTK inhibition
AuthorsGoutham Rajendran; Thanh-Hoang Nguyen-Vo; Hunter C. Murray; Robert A. Keyzers; Jordan A.J. McCone; Wanting Jiao; Paul H. Teesdale-Spittle; Binh P. Nguyen; Joanne E. Harvey
AffiliationsSchool of Chemical and Physical Sciences , Victoria University of Wellington , PO Box 600 , Wellington 6140, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, New Zealand Centre of Research Excellence , University of Auckland , Private Bag, 92019 Auckland , New Zealand; Centre for Biodiscovery , Victoria University of Wellington , New Zealand; School of Mathematics and Statistics , Victoria University of Wellington , New Zealand; Ferrier Research Institute , Victoria University of Wellington , New Zealand; School of Biological Sciences , Victoria University of Wellington , New Zealand
Striking two targets with one scaffold via benzo[d]imidazole-isatin conjugates as potent dual VEGFR-2/c-MET antagonists
AuthorsMohamed El-Naggar; Rofaida Salem; Mona M. Kabeel; Ihsan A. Shehadi; Wagdy M. Eldehna; Hatem A. Abdel-Aziz; Mahmoud S. Elkotamy
AffiliationsAdvanced Biotechnology Center, Research Institute for Sciences and Engineering, University of Sharjah, 27272, the United Arab Emirates; Department of Chemistry, College of Sciences, University of Sharjah, 27272, the United Arab Emirates; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh, University, P.O. Box 33516, Kafrelsheikh, Egypt; Students' Hospital, Mansoura University, Mansoura, Egypt; Applied Organic Chemistry Department, National Research Center, Dokki, Cairo 12622, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alsalam University, 31511 Tanta, Egypt
Cancer cell membrane-coated superparamagnetic iron oxide nanoparticles as a theranostic platform for magnetic hyperthermia and MR imaging
AuthorsYuchen Yuan; Satoshi Okada; Akira Sumiyoshi; Kazuki Miura; Hiroyuki Nakamura
AffiliationsSchool of Life Science and Technology, Institute of Science Tokyo, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan; Laboratory for Chemistry and Life Science, Institute of Integrated Research, Institute of Science Tokyo, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan; National Institutes for Quantum Science and Technology (QST), Anagawa 4-9-1, Inage-ku, Chiba, 263-8555, Japan
Incorporation of PeT fluorescent units into the pharmacophore of atypical dopamine transporter inhibitors
AuthorsMarie Louise Gram; Gisela Andrea Camacho-Hernandez; Amy Hauck Newman; Claus J. Loland; Mikael Bols
AffiliationsDepartment of Chemistry, Faculty of Science, University of Copenhagen, DK-2100 Copenhagen, Denmark; Laboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark; Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse − Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, United States
Synthesis and biological evaluation of optically active Z250–1659 as a synthetic lethal agent against BAP1-deficient mesothelioma cells
AuthorsTomohiro Tsutsumi; Airi Wada; Hikari Yamamoto; Momoko Sato; Sana Tsukioka; Mengshi Qiu; Koya Suzuki; Ayato Sato; Yuko Murakami-Tonami; Ichiro Hayakawa
AffiliationsGraduate School of Integrated Basic Sciences, Nihon University, 3-25-40, Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan; Laboratory of Cancer Molecular Genetics, Tokyo University of Technology Graduate School of Bionics, Computer and Media Sciences, Hachioji, Japan; Department of Pharmacology, Teikyo University School of Medicine, Itabashi-ku, Tokyo, Japan; Advanced Comprehensive Research Organization, Teikyo University, Itabashi-ku, Tokyo, Japan; Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Nagoya 464-8601, Japan; Center for One Medicine Innovative Translational Research (COMIT), Nagoya University, Nagoya, Aichi 464-8601, Japan; Advanced Innovation Development Unit, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan
Development of covalent agonists for the muscarinic acetylcholine receptor
AuthorsKatrin Eitel; Philipp Risel; Jonas Kaindl; Jürgen Einsiedel; Harald Hübner; Peter Gmeiner
AffiliationsDepartment of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany; FAU NeW – Research Center New Bioactive Compounds, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany
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