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Review Cycle Records

BIOORGANIC & MEDICINAL CHEMISTRY

Elsevier SCIE 非OA
2026新锐 3区2025中科院 3区2025 JCR Q1
51平均天数
50中位天数
31最短天数
79最长天数
3562025发文量

Paper Review Records

全部论文审稿周期

10 篇有效样本 · 按发表日期由新到旧排列
审稿天数=录用日期-收稿日期;保留 PDF/DOI/网页源链接

39 天

Functional mapping of the Trypanosoma cruzi serinome by fluorophosphonate activity-based protein profiling

作者Jaime A. Isern; María Gabriela Mediavilla; Exequiel O.J. Porta; Marcelo L. Merli; María Sol Ballari; Julia A. Cricco; Guillermo R. Labadie; Patrick G. Steel

作者单位Department of Chemistry, Durham University, Stockton Rd, DH1 3LE Durham, United Kingdom; Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET-UNR), Ocampo y Esmeralda, Rosario 2000, Argentina; Instituto de Química Rosario (IQUIR-CONICET-UNR), Universidad Nacional de Rosario, Argentina; Departamento de Química Orgánica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Argentina

PDF源文件 DOI 网页
74 天

Design, synthesis, and biological evaluation of novel phenylindole derivatives as P-gp inhibitors to overcome multidrug resistance in MCF-7/ADR cells

作者Zhikun Yang; Yingjia Ding; Keren Xu; Jiajia Han; Junzhe Hu; Sherien M. Bakry; Yi Hua; Hong Wang

作者单位College of Pharmaceutical Science & Jianxing Honors College, Zhejiang University of Technology, Hangzhou 310014, China; Zhejiang Key Laboratory of Green Manufacturing Technology for Chemical Drugs, Hangzhou 310014, China; Zhejiang-Egypt Joint Laboratory on Intelligent Discovery of Marine Drugs, Hangzhou 310014, China; Phytochemistry and Plant Systematics Department, National Research Centre, 33 El Bohouth St. Dokki, Giza 12622, Egypt

PDF源文件 DOI 网页
79 天

Discovery of SARS-CoV-2 PLpro covalent inhibitors enabled by a novel reversible covalent chloroalkyne warhead

作者Divakar Indukuri; Jazmin Galván Achi; Boopathi Sownthirarajan; Malla Reddy Gannarapu; Omar Lozano Ramos; Kiira Ratia; Priyajit Kaur; Rishi Vardhan Chunduru; Zuohuang Qi; Paulina Anguiano; Balaji Manicassamy; Lijun Rong; Rui Xiong

作者单位Department of Pharmacology & Toxicology, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, AZ, USA; Department of Microbiology and Immunology, College of Medicine, University of Illinois Chicago (UIC), Chicago, IL, USA; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Research Resources Center, University of Illinois Chicago (UIC), Chicago, IL, USA; Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.

PDF源文件 DOI 网页
31 天

Design, synthesis, antitumor estimation, and molecular docking of new imidazothiazolediones as potential dual EGFR and IDO1 inhibitors and apoptosis stimulators

作者Marwa T. Sarg; Fatma G. Abdulrahman; Yasmin S. Sheta; Eman S. Nossier; Ebtehal M. Husseiny

作者单位Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy (Girls), Al-Azhar University, Nasr City 11754, Cairo, Egypt; Department of Chemistry, Faculty of Pharmacy, Ahram Canadian University, 6th-October, Giza, Egypt; Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo 11754, Egypt

PDF源文件 DOI 网页
55 天

Evaluating the outputs of ARAE-based molecular generative model for synthetic accessibility and BTK inhibition

作者Goutham Rajendran; Thanh-Hoang Nguyen-Vo; Hunter C. Murray; Robert A. Keyzers; Jordan A.J. McCone; Wanting Jiao; Paul H. Teesdale-Spittle; Binh P. Nguyen; Joanne E. Harvey

作者单位School of Chemical and Physical Sciences , Victoria University of Wellington , PO Box 600 , Wellington 6140, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, New Zealand Centre of Research Excellence , University of Auckland , Private Bag, 92019 Auckland , New Zealand; Centre for Biodiscovery , Victoria University of Wellington , New Zealand; School of Mathematics and Statistics , Victoria University of Wellington , New Zealand; Ferrier Research Institute , Victoria University of Wellington , New Zealand; School of Biological Sciences , Victoria University of Wellington , New Zealand

PDF源文件 DOI 网页
56 天

Striking two targets with one scaffold via benzo[d]imidazole-isatin conjugates as potent dual VEGFR-2/c-MET antagonists

作者Mohamed El-Naggar; Rofaida Salem; Mona M. Kabeel; Ihsan A. Shehadi; Wagdy M. Eldehna; Hatem A. Abdel-Aziz; Mahmoud S. Elkotamy

作者单位Advanced Biotechnology Center, Research Institute for Sciences and Engineering, University of Sharjah, 27272, the United Arab Emirates; Department of Chemistry, College of Sciences, University of Sharjah, 27272, the United Arab Emirates; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh, University, P.O. Box 33516, Kafrelsheikh, Egypt; Students' Hospital, Mansoura University, Mansoura, Egypt; Applied Organic Chemistry Department, National Research Center, Dokki, Cairo 12622, Egypt; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alsalam University, 31511 Tanta, Egypt

PDF源文件 DOI 网页
33 天

Cancer cell membrane-coated superparamagnetic iron oxide nanoparticles as a theranostic platform for magnetic hyperthermia and MR imaging

作者Yuchen Yuan; Satoshi Okada; Akira Sumiyoshi; Kazuki Miura; Hiroyuki Nakamura

作者单位School of Life Science and Technology, Institute of Science Tokyo, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan; Laboratory for Chemistry and Life Science, Institute of Integrated Research, Institute of Science Tokyo, 4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan; National Institutes for Quantum Science and Technology (QST), Anagawa 4-9-1, Inage-ku, Chiba, 263-8555, Japan

PDF源文件 DOI 网页
65 天

Incorporation of PeT fluorescent units into the pharmacophore of atypical dopamine transporter inhibitors

作者Marie Louise Gram; Gisela Andrea Camacho-Hernandez; Amy Hauck Newman; Claus J. Loland; Mikael Bols

作者单位Department of Chemistry, Faculty of Science, University of Copenhagen, DK-2100 Copenhagen, Denmark; Laboratory for Membrane Protein Dynamics, Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark; Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse − Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, United States

PDF源文件 DOI 网页
33 天

Synthesis and biological evaluation of optically active Z250–1659 as a synthetic lethal agent against BAP1-deficient mesothelioma cells

作者Tomohiro Tsutsumi; Airi Wada; Hikari Yamamoto; Momoko Sato; Sana Tsukioka; Mengshi Qiu; Koya Suzuki; Ayato Sato; Yuko Murakami-Tonami; Ichiro Hayakawa

作者单位Graduate School of Integrated Basic Sciences, Nihon University, 3-25-40, Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan; Laboratory of Cancer Molecular Genetics, Tokyo University of Technology Graduate School of Bionics, Computer and Media Sciences, Hachioji, Japan; Department of Pharmacology, Teikyo University School of Medicine, Itabashi-ku, Tokyo, Japan; Advanced Comprehensive Research Organization, Teikyo University, Itabashi-ku, Tokyo, Japan; Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Nagoya 464-8601, Japan; Center for One Medicine Innovative Translational Research (COMIT), Nagoya University, Nagoya, Aichi 464-8601, Japan; Advanced Innovation Development Unit, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi 464-8681, Japan

PDF源文件 DOI 网页
45 天

Development of covalent agonists for the muscarinic acetylcholine receptor

作者Katrin Eitel; Philipp Risel; Jonas Kaindl; Jürgen Einsiedel; Harald Hübner; Peter Gmeiner

作者单位Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany; FAU NeW – Research Center New Bioactive Compounds, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nikolaus-Fiebiger-Str. 10, 91058 Erlangen, Germany

PDF源文件 DOI 网页

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样本口径2026 年最近 5 篇有效论文样本

平均审稿96.4 天

中位数77 天

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