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Molecular Therapy Methods & Clinical Development journal cover Medicine
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Review Cycle Records

Molecular Therapy Methods & Clinical Development

Elsevier SCIE OA
2026 Emerging Zone 22025 CAS Zone 22025 JCR Q2
172.1Average days
144Median days
42Fastest days
463Longest days
2432025 publications

Paper Review Records

All Paper Review Records

10 valid samples · Newest publication first
Review days = acceptance date − received date. PDF, DOI, and publisher-page sources are retained.

463 days

Inhibition of immune response reduces pathology in dorsal root ganglia and peripheral nerves in cynomolgus macaques following AAV gene therapy

AuthorsBranka Grubor; Kate L. Henry; Su Jing Chan; Mark Sheehan; Anumeha Shah; Alex Pellerin; Judy Bai; Prasad Nadella; Santhosh Bommegowda; Patrick Cullen; Eric Tien; Vivian Chen; Nicholas P. van der Munnik; Stephanie White-Hunt; Edward D. Plowey; Stefan Hamann; Amanda J. Guise; Shanqin Xu; Melissa Kirkland; Jessica Doherty; Eugenia Lyashenko; Guruharsha Bhat; Kelly Glajch; Shih-Ching Lo; Davide Gianni; Pete Clarner; Jake Gagnon; Jenhwa Chu; Kalyani Nambiar; Mukesh Lulla; Fengmei Zheng; Asmerom Weldeab; Dan Bartlett; Amos Gutnick; Taylor Reynolds; Kan Zhu; Dann Huh; Thomas M. Carlile; James Fikes; Patrick Trapa; Junghae Suh; Dale Morris; Linda Burkly

AffiliationsBiogen, Cambridge, MA 02142, USA; Charles River Laboratories, Durham, NC 27703, USA

Source PDF DOI Publisher page
150 days

Leveraging the active conformation of LFA-1 as a potential target for hematological malignancies

AuthorsAbhishek Puthenveetil; Guy Biber; Batel Sabag; Meirav Kedmi; Avigdor Abraham; Noah Joseph; Mira Barda-Saad

AffiliationsThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 5290002, Israel; The Chaim Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel; Sackler School of Medicine, Tel- Aviv University, Tel-Aviv, Israel

Source PDF DOI Publisher page
234 days

AAV-PHP.eB achieves superior neuronal transduction over AAV9 in pigtail macaques following intracerebroventricular administration

AuthorsMichal G. Fortuna; Lyle H. Nyberg; Naz Taskin; Avery Hunker; Natalie Weed; Kathryn Gudsnuk; Melissa Berg; Boaz P. Levi; Ed Lein; Jonathan T. Ting

AffiliationsAllen Institute for Brain Science, Seattle, WA, USA; Washington National Primate Research Center, Seattle, WA, USA; Department of Neurological Surgery, University of Washington, Seattle, WA, USA; Department of Neurobiology & Biophysics, University of Washington, Seattle, WA, USA

Source PDF DOI Publisher page
84 days

Nonclinical toxicity study duration in AAV gene therapy development: Evidence from industry survey supports adequacy of short-term assessments

AuthorsBasel T. Assaf; David Edwards; Shawn Jay Berens; Brian Lauritzen; Christelle Pierrot; Francis Fonyuy Tukov; Cristina Bertinetti-Lapatki; Manuela Braun; Kai Schaefer; Jessica L. Lynch

AffiliationsSanofi, Cambridge, MA 02141, USA; UCB Pharma, Slough, UK; Eli Lilly and Company, Indianapolis, IN 46285, USA; Novo Nordisk A/S, Maaloev, Denmark; Astellas Pharma B.V., Leiden, the Netherlands; Novartis Pharmaceuticals Corporation, East Hanover, NJ 07936, USA; Roche Innovation Center, 4070 Basel, Switzerland; Bayer AG, 13342 Berlin, Germany; AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany; Johnson & Johnson Innovative Medicine, Spring House, PA 19477, USA

Source PDF DOI Publisher page
42 days

Gene therapy supports long-term reconstitution of patient hematopoietic stem cells in deficiency of adenosine deaminase 2

AuthorsChiara Rigamonti; Dimitri Bulté; Federica Barzaghi; Cristina Mesa-Nuñez; Luca Basso-Ricci; Emanuela Pettinato; Camilla Visconti; Sara Degl’Innocenti; Francesco Gazzo; Fabrizio Benedicenti; Sergio Arévalo; Pamela Quaranta; Francesca Sanvito; Roberta Caorsi; Francesca Schena; Michela Lupia; Silvia Federici; Antonella Insalaco; Fabrizio De Benedetti; Serena Scala; Maurizio Miano; Francesca Conti; Maria Pia Cicalese; Eugenio Montini; Marco Gattorno; Carlo Dufour; Alessandro Aiuti; Alessandra Mortellaro

AffiliationsSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; Vita-Salute San Raffaele University, 20132 Milan, Italy; Pediatric Immunohematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; GLP Test Facility, San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; Pathology Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; Department of Electronics, Information and Bioengineering, Politecnico di Milano, 20133 Milan, Italy; UOC Rheumatology and Autoinflammatory Diseases, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy; Hematology Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy; Division of Rheumatology, Bambino Gesù Children’s Hospital, ERN-RITA Center, IRCCS, 00165 Rome, Italy; Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy; Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy

Source PDF DOI Publisher page
170 days

SLC20A1 knockout to stably express a fusogenic gibbon ape leukemia virus envelope glycoprotein for lentiviral vector production

AuthorsRodrigo José Nogueira; Ana Filipa Rodrigues; Daniel Alexandre Mestre; Ana Sofia Coroadinha

AffiliationsiBET - Instituto de Biologia Experimental e Tecnológica, Apartado 12, 2781-901 Oeiras, Portugal; Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. da República, 2780-157 Oeiras, Portugal; LASIGE, Faculdade de Ciências da Universidade de Lisboa, 1749-016 Lisboa, Portugal

Source PDF DOI Publisher page
138 days

Transcriptional changes in non-human primate tissues after intrathecal delivery of serotype 9 adeno-associated viral vector: Insights into organ toxicities

AuthorsFumiaki Aihara; Matthew Mardo; Vera Ruda; Tony del Rio; Karine Bigot; Jochen Singer; Megumi Onishi-Seebacher; Philippe Couttet; Keith Mansfield; Eloise Hudry

AffiliationsNovartis Biomedical Research, Cambridge, MA, USA; Novartis Biomedical Research, Basel, Switzerland; Novartis Biomedical Research, San Diego, CA, USA

Source PDF DOI Publisher page
125 days

Therapeutic mRNA delivery of CRISPR-Cas9 to the trabecular meshwork reverses ocular hypertension in myocilin glaucoma

AuthorsSam Yacoub; Balasankara Reddy Kaipa; Linya Li; Sarahi Rios; Ramesh Kasetti; Prabhavathi Maddineni; Abbot F. Clark; Gulab S. Zode

AffiliationsDepartment of Pharmacology and Neuroscience and North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX 76107, USA; Gavin Herbert Eye Institute-Center for Translational Vision Research, Department of Ophthalmology, Department of Physiology and Biophysics, University of California, Irvine, Irvine School of Medicine, Irvine, CA 92697, USA; Department of Ophthalmology, School of Medicine, University of Missouri, Columbia, MO 65212, USA

Source PDF DOI Publisher page
98 days

Bedside manufacturing of engineered stem cells using gene therapy foam

AuthorsCarrie L. Cummings; Sirkka B. Stephan; Katelyn Fitzgerald; Matthias T. Stephan

AffiliationsTranslational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA; Department of Bioengineering and Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA 98109, USA; Department of Medicine, Division of Medical Oncology, University of Washington, Seattle, WA 98195, USA

Source PDF DOI Publisher page
217 days

A potency and toxicology study on tolerability of cryopreserved mesenchymal stem cell product with DMSO in septic mice and nude rats

AuthorsYan Wang; Glinton Hanover; Aidan B.P. Murray; Mahmoud Salkhordeh; Yuan Tan; Chi Wang; Jia-Pey Wang; Andrea McRae; Yupu Deng; Maria Florian; Pramod Sahadevan; Duncan J. Stewart; Lauralyn Mclntyre; Luciana Souza-Moreira; Shirley H.J. Mei

AffiliationsRegenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada; Department of Medicine, University of Ottawa, Ottawa, ON, Canada

Source PDF DOI Publisher page

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I work in environmental engineering and need an SCI paper published within three months. I have no grant funding or prominent co-author. Which journals could I target?

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Machine Learning and Life-Cycle Assessment for Predicting and Optimizing Carbon Emissions in Urban Wastewater Treatment

SampleLatest 5 valid paper samples from 2026

Average review96.4 days

Median77 days

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