LABORATORY INVESTIGATION

AuthorsKeke Wang; Xu Cai; Chunyan Wu; Yan Huang; Xiaoyan Chen; Shenglei Li; Jiansha Li; Yan Li; Li Gong; Xiaorong Mu; Xinyue Zhang; Guangjian Yang; Yuan Li

AffiliationsDepartment of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China; Department of Pathology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China; Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China; Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Department of Pathology, Tangdu Hospital, Air Force Medical University (Fourth Military Medical University), Xi'an, China; Department of Pathology, Union Hospital, Fujian Medical University, Fuzhou, China; Department of Respiratory Medicine, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China

AuthorsOskari Rahkola; Henna Karjalainen; Ville K. Äijälä; Meeri Kastinen; Vilja V. Tapiainen; Hanna Elomaa; Onni Sirkiä; Vesa-Matti Pohjanen; Maarit Ahtiainen; Olli Helminen; Taneli T. Mattila; Outi Lindgren; Erkki-Ville Wirta; Jukka Rintala; Sanna Meriläinen; Juha Saarnio; Tero Rautio; Toni T. Seppälä; Jan Böhm; Jukka-Pekka Mecklin; Anne Tuomisto; Markus J. Mäkinen; Juha P. Väyrynen; Päivi Sirniö

AffiliationsTranslational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital, and University of Oulu, Oulu, Finland; Research Program in Systems Oncology, University of Helsinki, Helsinki, Finland; Department of Environmental and Biological Sciences, University of Eastern Finland, Kuopio, Finland; Central Finland Biobank, Hospital Nova of Central Finland, Well Being Services County of Central Finland, Jyvaskyla, Finland; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland; Faculty of Medicine and Health Technology, Tampere University and Tays Cancer Centre, Tampere University Hospital, Tampere, Finland; Department of Gastrointestinal Surgery, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland; Applied Tumor Genomics, Research Program Unit, University of Helsinki, Helsinki, Finland; Department of Pathology, Hospital Nova of Central Finland, Well Being Services County of Central Finland, Jyvaskyla, Finland; Department of Education and Research, Well Being Services County of Central Finland, Jyvaskyla, Finland; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyvaskyla, Finland

AuthorsThais Maloberti; Margherita Nannini; Annalisa Astolfi; Maria Concetta Nigro; Livia Gozzellino; Alice Costa; Maria Giulia Pirini; Antonio De Leo; Marco Grillini; Bruno Vincenzi; Elena Fumagalli; Antonella Brunello; Giovanni Grignani; Sandra Aliberti; Angela Dalia Ricci; Fabio Gelsomino; Giovanni Tallini; Maria Abbondanza Pantaleo; Dario de Biase

AffiliationsSolid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy; Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Pathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Department of Medical Oncology, Campus Biomedico University of Rome, Rome, Italy; Medical Oncology Unit 2, Fondazione IRCCS, Istituto Nazionale dei Tumori, Milano, Italy; Department of Oncology, Medical Oncology 1, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy; Candiolo Cancer Institute, FPO – IRCCS, Candiolo, Italy; Medical Oncology Unit, National Institute of Gastroenterology, IRCCS “S. de Bellis” Research Hospital, Castellana Grotte, Italy; Department of Oncology and Hematology, Division of Oncology, University Hospital of Modena, Modena, Italy; Department of Pharmacy and Biotechnology (FaBit), University of Bologna, Bologna, Italy

AuthorsElena Baraznenok; Huai-Ching Hsieh; Lydia Lan; Eric Q. Konnick; Sandy Figiel; Srinivasa R. Rao; Dan J. Woodcock; Ian G. Mills; Freddie C. Hamdy; Jacob E. Valk; Kelly T. Carter; Ming Yu; Thomas G. Paulson; Suzanne Dintzis; William M. Grady; Jonathan T.C. Liu

AffiliationsDepartment of Bioengineering, University of Washington, Seattle, Washington; Department of Mechanical Engineering, University of Washington, Seattle, Washington; Department of Bioengineering, University of California Berkeley, Berkeley, California; Department of Bioengineering, Stanford University, Stanford, California; Department of Pathology, Stanford University, Stanford, California; Department of Biology, University of Washington, Seattle, Washington; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK; Big Data Institute, University of Oxford, Oxford, UK; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, Washington; Department of Medicine, University of Washington, Seattle, Washington

AuthorsLena Haeberle-Graser; Marie Schulte; Carolin Mueller; Sebastian Haensch; Martin Schlensog; Irene Esposito

AffiliationsInstitute of Pathology, Heinrich Heine University & University Hospital Duesseldorf, Germany; Barmherzige Brueder Hospital Regensburg, Department of Anesthesiology and Surgical Intensive Care Medicine, Germany; Department of Pediatrics, Helios Klinikum Krefeld, Academic Hospital RWTH Aachen, Germany; Center for Advanced Imaging (CAi), Heinrich Heine University Duesseldorf, Germany

AuthorsAlessandro Gambella; Luca Mastracci; Chiara Trambaiolo; Luca Guastini; Michele Paudice; Simona Pigozzi; Silvia Bozzano; Valentina Angerilli; Alessandro Caputo; Paola Parente; Alessandro Vanoli; Matteo Fassan; Federica Grillo

AffiliationsDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy; IRCCS Azienda Ospedaliera Metropolitana, Genoa, Italy; Pathology Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy; Department of Otolaryngology and Head and Neck Surgery, IRCCS San Martino Polyclinic Hospital, Genoa, Italy; Surgical Pathology Unit, ULSS2 Marca Trevigiana, Treviso, Italy; Department of Pathology, University Hospital of Salerno, Salerno, Italy; Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi, Italy; Pathology Unit, Azienda Ospedaliero Universitaria Policlinico Foggia, Foggia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy; Unit of Anatomic Pathology, IRCCS San Matteo Hospital Foundation, Pavia, Italy; Veneto Institute of Oncology IOV-IRCCS, Padua, Italy; Department of Medicine (DIMED), University of Padua, Padua, Italy

AuthorsZeynep E. Kain; Emma Schuurman; Ximena Baez-Navarro; Henrik Høeg; Prasanth Kanneganti; Nils ’t Hart; Carolien H.M. van Deurzen

AffiliationsDepartment of Pathology, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Pathology, Isala, Zwolle, the Netherlands; Visiopharm A/S, Hørsholm, Denmark; Boston Cell Standards Inc, Boston, Massachusetts

AuthorsLiu Liu; Stephanie L. Graff; Liang Cheng; Yihong Wang

AffiliationsDepartment of Pathology and Laboratory Medicine, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island; Division of Medical Oncology, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island

AuthorsOmar Youssef; Lars Selander; Shuyu Zheng; Lilla Csellar; Satu Hänninen; Jing Tang; Olli Carpén; Anna Ray Laury

AffiliationsDepartment of Pathology, University of Helsinki, Helsinki, Finland; Clinical and Chemical Pathology Department, National Cancer Institute, Cairo University, Cairo, Egypt; Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden; Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; KIGene Core Facility, Karolinska Institutet, Stockholm, Sweden; Helsinki Biobank, Helsinki, Finland; University of Helsinki and Helsinki University Hospital, Helsinki, Finland

AuthorsMikhail S. Ermakov; Sigrid Regauer; Karl Kashofer

AffiliationsDiagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria