生物学
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Integrative chemical genetics platform identifies condensate modulators linked to neurological disorders
作者Dylan Poch; Chandrayee Mukherjee; Sunanda Mallik; Vanessa Todorow; E. F. Elsiena Kuiper; Nalini Dhingra; Yulia V. Surovtseva; Christian Schlieker
作者单位1. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511; 2. Max Planck Institute of Biophysics, Mechanisms of Cellular Quality Control, Frankfurt a. M., Germany 60438; 3. Yale Center for Molecular Discovery, Yale University, West Haven, CT 06516; 4. Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520
Novel KIF22 variants disrupt mitosis in human chondrocytes and expand SEMDJL2 mechanisms
作者Amila Šemić; Kazette Yuen Yu Chan; Pricila Bernardi; Karina C. Silveira; Cynthia Silveira; Denise P. Cavalcanti; Peter Kannu; Jason Stumpff
作者单位1. Department of Molecular Physiology and Biophysics, University of Vermont, Burlington, VT 05405; 2. Department of Medical Genetics, University of Calgary, Canada, T6G 2H7; 3. Pediatrics Department of University Hospital, Federal University of Santa Catarina, Brazil, 88040-900; 4. Skeletal Dysplasia Group, Medical Genetics Department, Science Medical Faculty, University of Campinas (UNICAMP), Brazil, 13083-888; 5. Neurology Department, University of Campinas (UNICAMP), Campinas, SP, Brazil, 13083-888
A role for the Stentor syntaxin protein in post-wound cell survival
作者Ambika V. Nadkarni; Ulises Diaz; Ramon Rodriguez; Kevin S. Zhang; Sindy K.Y. Tang; Wallace F. Marshall
作者单位1. Department of Mechanical Engineering, Stanford University, Stanford, CA 94305.; 2. Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158.
Nuclear morphology and chromatin compaction modulate T cell cytoskeletal remodeling and immune synapse formation
作者Ivan Rey-Suarez; Aashli Pathni; Frank Fazekas; Matthew Connell; Arpita Upadhyaya
作者单位1. Bio-imaging Resource Center, The Rockefeller University, New York, NY 10065, USA; 2. Institute for Physical Science and Technology, University of Maryland, College Park, MD 20742; 3. Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA 98109; 4. Biological Sciences Graduate Program, University of Maryland, College Park, MD 20742; 5. Biophysics Program, University of Maryland, College Park, MD 20742; 6. Department of Physics, University of Maryland, College Park, MD 20742
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