生物学
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9 篇有效样本 · 按发表日期由新到旧排列
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Targeting of conserved spike epitopes enables broad antibody neutralisation of diverse bat sarbecoviruses
作者Ayush Upadhyay; Jeffrey Seow; Yilmaz Alguel; Joseph Newman; Nazia Thakur; Abigail L. Hay; Jerry C. H. Tam; Andrea Nans; Richard J. Orton; Dalan Bailey; Peter Cherepanov; Katie J. Doores
作者单位1. Department of Infectious Diseases, School of Immunology & Microbial Sciences, King’s College London, London, United Kingdom; 2. Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, United Kingdom; 3. The Pirbright Institute, Woking, Surrey, United Kingdom; 4. Structural Biology Science Technology Platform, The Francis Crick Institute, London, United Kingdom; 5. MRC-University of Glasgow Centre for Virus Research, The University of Glasgow, Glasgow, United Kingdom; 6. Department of Infectious Disease, South Kensington Campus, Imperial College London, London, United Kingdom
Breadth of ACE2 receptor usage predicts host range and antigenic relatedness across bat sarbecoviruses
作者Nazia Thakur; Joseph Newman; Dongchun Ni; Jeffrey Seow; Abigail L. Hay; Yeonjae Lee; Ayush Upadhyay; Babatunde E. Ekundayo; John A. Hammond; Thomas P. Peacock; Kelvin Lau; Katie J. Doores; Dalan Bailey
作者单位1. The Pirbright Institute, Pirbright, Woking, United Kingdom; 2. Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; 3. School of Pharmacy, International Cancer Center, Guangdong Key Laboratory of Genome Instability and Human Disease Prevention, Shenzhen University Medical School, Shenzhen, China; 4. Department of Infectious Diseases, School of Immunology & Microbial Sciences, King’s College London, London, United Kingdom; 5. Laboratory of Biological Electron Microscopy (LBEM), Institute of Physics, School of Basic Sciences, École Polytechnique Fédérale de Lausanne, Rte Cantonale, Lausanne, Switzerland; 6. Department of Infectious Disease, Imperial College London, London, United Kingdom; 7. Protein Production and Structure Core Facility (PTPSP), School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
Antibodies targeting phage fiber and nozzle proteins impair Acinetobacter baumannii phage therapy by blocking infection and promoting immune clearance
作者Heng Xue; Xinfeng Li; Guibo Rao; Fen Hu; Mingyue Zhong; Paulina Miernikiewicz; Rui Qiu; Sheng Cao; Krystyna Dąbrowska; Hang Yang
作者单位1. State Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China; 2. University of Chinese Academy of Sciences, Beijing, China; 3. Key Laboratory of Ministry of Education for Gastrointestinal Cancer, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, China; 4. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland; 5. Faculty of Medicine, Wroclaw University of Science and Technology, Wrocław, Poland; 6. Hubei Jiangxia Laboratory, Wuhan, China
Monovalent cations differentially regulate the activity of eukaryotic fluoride channels and impact fluoride resistance
作者Chia-Yu Kang; Sahar Heidari; Sabrina Kolb; Minjun An; Melanie D. Ohi; Hedieh Torabifard; Randy B. Stockbridge
作者单位1. Program in Biophysics, University of Michigan, Ann Arbor, Michigan, United States of America; 2. Department of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, Texas, United States of America; 3. Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America; 4. Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America; 5. Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America
MucD regulates alginate biosynthesis through the proteolytic control of AlgX and AlgK in Pseudomonas aeruginosa
作者Yujun Jiang; Xin-Fu Yan; Rya Ero; Chao Wang; Kanaga Sabapathy; Yong-Gui Gao
作者单位1. School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; 2. NTU Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore
The nematode Caenorhabditis elegans has a cationic amphiphilic drug (CAD) defense system
作者Levon Tokmakjian; Duhyun Han; Kateryna Sihuta; Aanchal Aggarwal; Somayeh Pirhadi; Yao Wang; Andrew R. Burns; Brittany Cooke; Siyue Ren; Marios Gavrielatos; Jiabao Liu; Henry M. Krause; Carolyn L. Cummins; Justin Nodwell; David R. Koes; Peter J. Roy
作者单位1. Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada; 2. The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; 3. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; 4. Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America; 5. Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada; 6. Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada
Myelin sheath lengths in the central nervous system scale to axon diameter via oligodendroglial Piezo1
作者Amanda R. Young; Ashley Galfano; Jacob Reyngoudt; Ryan W. Lewis; Martha Cash; Beckam Polis; Myah Zalusky; Avipsha Datta; Marie E. Bechler
作者单位1. Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, New York, United States of America; 2. Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, New York, United States of America
Regeneration programs buffer genetic defects in animal development
作者Kazunori Ando; Sushant Bangru; John Welsby; John D. Thompson; Kenneth D. Poss
作者单位1. Morgridge Institute for Research, Madison, Wisconsin, United States of America; 2. Department of Cell and Regenerative Biology, University of Wisconsin--Madison, Madison, Wisconsin, United States of America; 3. Department of Cell Biology, Duke University School of Medicine, Durham, North Carolina, United States of America
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