医学
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Centanafadine (Simtriyo®): a first-in-class triple reuptake inhibitor approved for attention-deficit/hyperactivity disorder (ADHD)
作者Longqin Hu
作者单位1. Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, USA; 2. The Cancer Institute of New Jersey, New Brunswick, USA
Design, synthesis, biological activity and computational simulation evaluation of pyrimidine-2-aminoacetamide derivatives as cholinesterase inhibitors
作者Yi-Xuan Wang; Shi-Hao Qin; Qian Liu; Xue-Wei Zhou; Chao-Yue Zhang; Zheng-Yue Ma
作者单位1. College of Pharmaceutical Sciences, Institute of Life Science and Green Development, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding, China; 2. Technology Center of Shijiazhuang Customs District, Baoding, China
Zidesamtinib (Jideytro®): a new selective, brain-penetrant ROS1 inhibitor approved for the treatment of ROS1-positive non-small cell lung cancer
作者Sumi Lee; Longqin Hu
作者单位1. School of Pharmacy and Institute of New Drug Development, Jeonbuk National University, Jeonju, Republic of Korea; 2. Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, The State University of New Jersey, 160 Frelinghuy sen Road, Piscataway, Rutgers, USA; 3. The Cancer Institute of New Jersey, New Brunswick, USA
Dual-target carbonic anhydrase inhibitors in cancer therapy: progress, challenges, and opportunities
作者Meizhen Luo; Yong Wang; Yinmei Xia; Qin-Min Wang; Jifa Zhang; Lianhai Shan
作者单位1. School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, China; 2. Department of Neurology, Laboratory of Neuro-system and Multimorbidity, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China
Enhancement of antitumor activity through structural optimization of 2-(Benzylamino)-thieno[2,3-d]pyrimidin-4(3H)-ones
作者Nazariy Pokhodylo; Kostiantyn Levchenko; Nataliya Finiuk; Yuliia Kozak; Olha Klyuchivska; Rostyslav Stoika
作者单位1. Ivan Franko National University of Lviv, Lviv, Ukraine; 2. Institute of Cell Biology, National Academy of Sciences of Ukraine, Lviv, Ukraine
The genus Laggera : an extensive review of phytochemistry, pharmacology, clinical study, and chemical modification
作者Huynh Thi Ngoc Ni; Do Thi Lan Huong; Duong Quang Huan; Huy Dinh Vu; Tran Thi Thanh Thuy; Nguyen Thanh Hao; Dong Huy Gioi; Dinh Thi Thu Huong; Ninh The Son
作者单位1. Faculty of Education, Ha Tinh University, Hatinh, Vietnam; 2. Department of Plant Science, Faculty of Biology and Agriculture, Hanoi Pedagogical University (HPU2), Phutho, Vietnam; 3. Faculty of Chemistry, Hanoi Pedagogical University, Phutho, Vietnam; 4. Department of Chemistry, Vietnam National University of Forestry, Xuan Mai, Hanoi, Vietnam; 5. Faculty of Biotechnology, Vietnam National University of Agriculture, Gia Lam, Hanoi, Vietnam; 6. Faculty of Education, Nghe An University, Vinh, Vietnam; 7. Institute of Chemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam
Indole-based derivatives as anticancer agents: recent advances in structure–activity relationships and biological mechanisms
作者Aashik Malik; Mayank Yadav; Jai Parkash Kadian; Komal Mishra; Ramsha; Anurag Rathore; Manisha; Nishant Rathour
作者单位1. Adarsh Vijendra Institute of Pharmaceutical Sciences, Shobhit University, Gangoh, India
Design and mechanistic evaluation of chalcone–quinoline–triazole hybrids as antifungal CYP51 inhibitors
作者Rudi Hendra; Rahmad Setiawan Rabby; Tengku Anggia Fitri; Hilwan Yuda Teruna; Neni Frimayanti
作者单位1. Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Riau, Pekanbaru, Indonesia; 2. Centre of Biological Innovation for Regenerative and Natural Applications, Universitas Riau, Pekanbaru, Indonesia; 3. Master Degree Program, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Riau, Pekanbaru, Indonesia; 4. Riau College of Pharmaceutical Sciences, Tampan, Pekanbaru, Indonesia
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