医学
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Multi-target-directed drugs: new additions in 2025 and post-marketing safety surveillance of drugs marketed in 2022–2024
作者Piotr Ryszkiewicz; Marta Baranowska-Kuczko; Barbara Malinowska; Eberhard Schlicker
作者单位1. Department of Experimental Physiology and Pathophysiology, Medical University of Białystok, Białystok, Poland; 2. Department of Experimental Physiology and Pathophysiology, Department of Clinical Pharmacy, Medical University of Białystok, Białystok, Poland; 3. Department of Pharmacology and Toxicology, University of Bonn, Bonn, Germany
Aripiprazole modulates splenic microbiota and immune response elicited by single prolonged stress in rats
作者Peter Vargovic; Andrej Tillinger; Lubica Horvathova; Lila Dziewiczova; Jana Osacka
作者单位1. Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia; 2. Faculty of Natural Sciences, Department of Animal Physiology and Ethology, Comenius University in Bratislava, Bratislava, Slovakia
Phase-specific involvement of BDNF–TrkB signaling in HSV-1–induced herpetic pain and its transition to postherpetic neuralgia-like pain
作者Ichiro Takasaki; Arata Inoue; Aoi Yoshida; Yuya Ashihara; Hiroyuki Mori
作者单位1. Laboratory of Pharmacology, Faculty of Engineering, University of Toyama, Toyama, Japan; 2. Graduate School of Science and Engineering, University of Toyama, Toyama, Japan; 3. Graduate School of Pharma-Medical Sciences, University of Toyama, Toyama, Japan; 4. Laboratory of Pharmacology, Graduate School of Pharma-Medical Sciences, University of Toyama, Toyama, Japan
The onset of posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS) with the use of decongestant agents: a European pharmacovigilance analysis
作者Antonietta Anatriello; Andrea Cantone; Ciro Pentella; Maria Giovanna Vastarella; Annamaria Mascolo; Annalisa Capuano; Concetta Rafaniello
作者单位1. Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, Napoli, Italy; 2. Department of Experimental Medicine, Section of Pharmacology “L. Donatelli”, University of Campania “Luigi Vanvitelli”, Napoli, Italy; 3. Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, Department of Experimental Medicine, Section of Pharmacology “L. Donatelli”, University of Campania “Luigi Vanvitelli”, Naples, Italy; 4. Department of Women, Child and General and Special Surgery, University of Campania “Luigi Vanvitelli”, Naples, Italy; 5. Department of Life Sciences, Health, and Health Professions, Link Campus University, Rome, Italy
Topical latanoprost acid for female androgenetic alopecia: a pilot proof-of-concept trial with mechanistic evidence of prostaglandin F2α receptor activation
作者Adriana Rakowska; Małgorzata Dutkiewicz; Oliwia Zegrocka-Stendel; Dorota Dymkowska; Grzegorz Huszcza; Maciej Wierzbicki; Jarosław Walczak; Lidia Rudnicka; Katarzyna Koziak
作者单位1. Department of Dermatology, Medical University of Warsaw, Warszawa, Poland; 2. Department of Biochemistry and Nutrition, Centre for Preclinical Research and Technologies, Medical University of Warsaw, Warszawa, Poland; 3. Laboratory of Cellular Metabolism, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warszawa, Poland; 4. Department of Pharmacy, Pharmaceutical Research Institute, Warszawa, Poland; 5. BioResearch Pharma S.A., Warszawa, Poland; 6. Department of Biosystems and Soft Matter, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warszawa, Poland
Decoding the serotonin–alcohol crosstalk: the role of central serotonergic dysregulation in alcohol use disorder
作者Magdalena Zaniewska
作者单位1. Department of Brain Biochemistry, Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland; 2. Department of Affective Cognitive Neuroscience, Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland
Investigating the interaction between aryl hydrocarbon receptor and methotrexate: implications for treatment resistance in rheumatoid arthritis patients
作者Anna Wajda; Gabriela Filipowicz; Yana Kaliberda; Barbara Stypińska; Tomasz Kmiołek; Ewa Kuca-Warnawin; Małgorzata Jarończyk; Agata Matusiewicz; Bożena Jaszczyk; Małgorzata Stasiek; Anna Felis-Giemza; Katarzyna Bazała; Adam Ejma-Multański; Diana Bogucka; Ewa Modzelewska; Marzena Olesińska; Agnieszka Paradowska-Gorycka
作者单位1. Department of Molecular Biology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warszawa, Poland; 2. Department of Pathophysiology and Immunology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warszawa, Poland; 3. National Medicines Institute, Warszawa, Poland; 4. Paediatric Regional Centre for Digital Medicine, The Children’s Memorial Health Institute, Warsaw, Poland; 5. Department of Connective Tissue Diseases, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warszawa, Poland; 6. Department of Outpatient Clinics, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warszawa, Poland; 7. Biologic Therapy Center, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warszawa, Poland
Hypocholesterolemic agents and the gut microbiota: a review of interactions and modulatory activity
作者Manuel Mântua E. Garcia; Virginie Xavier; Ricardo C. Calhelha; Sandrina A. Heleno
作者单位1. CIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, Bragança, Portugal
Italian regional data and oropharyngeal adverse events to drugs and vaccines: insights from a 3-year spontaneous reporting (2022–2024)
作者Liberata Sportiello; Mario Gaio; Alessia Zinzi; Gaetano La Mantia; Vera Panzarella; Giuseppe Colella; Paola Martina Marra; Laura Sottosanti; Simona Potenza; Giacomo Oteri; Martina Coppini; Giuseppe Seminara; Rodolfo Mauceri; Ilaria Morreale; Vittorio Fusco; Giuseppina Campisi; Annalisa Capuano
作者单位1. Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, University of Campania “Luigi Vanvitelli”, Naples, Italy; 2. Department of Experimental Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy; 3. Department of Life Science, Health, and Health Professions, Link Campus University, Roma, Italy; 4. Unit of Oral Medicine and Dentistry for Fragile Patients, Department of Rehabilitation, Fragility, and Continuity of Care, University Hospital Palermo, Palermo, Italy; 5. Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy; 6. Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy; 7. Oral and Maxillofacial Surgery Unit, Multidisciplinary Department of Medical - Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”, Naples, Italy; 8. Complex Operative Unit of Stomatological surgery in Developmental age, University of Campania “Luigi Vanvitelli”, Naples, Italy; 9. Italian Medicines Agency, Rome, Italy; 10. Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Palermo, Italy; 11. Internal Medicine, Pharmacovigilance and Clinical Pharmacology Unit, Department of Promoting Health, Maternal- Infant, Excellence and Internal and Specialized Medicine (PROMISE) G. D’Alessandro, Sicilian Regional Pharmacovigilance Centre, University of Palermo, Palermo, Italy; 12. Oncology Unit, Department of Medicine and Translational Medicine Unit, DAIRI - Department of Integration, Research and Innovation, “SS Antonio e Biagio e C. Arrigo” Hospital, Alessandria, Italy; 13. Department of Biomedicine, Neuroscience and Advanced Diagnostic, University of Palermo, Palermo, Italy
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