医学
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Barriers and facilitators to the implementation of pharmacogenomic testing for antidepressants use in primary care: a systematic review using the consolidated framework for implementation research
作者Muireann Counihan; Deirdre Cushen; Sookyung Kwak; Amy Allen; Donnchadh Fitzsimons Mac Giolla Chuda; Weronika Romanska; Ibrahim Nakchbandi; Rose Reynolds; Chad Bousman; Mark Ledwidge; Joseph Gallagher; Cristín Ryan
作者单位1. School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland; 2. Department of Medical Genetics, University of Calgary, Calgary, Canada; 3. School of Medicine, University College Dublin, Belfield, Ireland
Amplicon-based long-read sequencing for accurate CYP2D6 gene deletion and duplication detection using CYP2D7 as a reference gene
作者Kiflu Gebremicael Tesfamicael; Michael Musker; David L. Adelson; Martin David Lewis
作者单位1. Lifelong Health, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, Australia; 2. School of Biological Sciences, Adelaide University, Adelaide, Australia; 3. South Australian Research and Development Institute (SARDI), Department of Primary Industries and Regions, Adelaide, Australia; 4. School of Nursing and Midwifery, College of Health, Adelaide University, Adelaide, Australia; 5. South Australian Museum, Adelaide, Australia
Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder a retrospective cohort study CYP2D6 genotype and antidepressant response
作者Aleksandra Petković Ćurčin; Aleksandra Jeremić; Danilo Joković; Gordana Šupić; Katarina Simić; Filip Milosavljević; Zvezdana Stojanović; Marin M. Jukić
作者单位1. Faculty of Medicine, Military Medical Academy, University of Defense, Belgrade, Serbia; 2. Institute for Medical Research, Military Medical Academy, Belgrade, Serbia; 3. Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia; 4. Clinic for Psychiatry, Military Medical Academy, Belgrade, Serbia; 5. Department of Psychiatry, Berkshire Medical Center, Pittsfield, United States of America; 6. Department of Psychiatry and Psychotherapy, School of Medicine, Technische Universität München, München, Germany; 7. Department of Physiology and Pharmacology, Karolinska Institute, Solna, Sweden
Large-scale analysis demonstrates the influence of CYP2C19 genotype on specific SSRI side effects
作者Chris Eijsbouts; Yunxuan Jiang; James R. Ashenhurst; Julie M. Granka; Steven Pitts; Adam Auton; Noura S. Abul-Husn; Alison Chubb; R. Ryanne Wu
作者单位1. 23andMe Research Institute, Palo Alto, USA
Effects of CYP3A4, CYP3A5 , and ABCB1 genetic variants on tacrolimus metabolism during the early period after kidney transplantation
作者Nahathai Dukaew; Kajohnsak Noppakun; Mingkwan Na Takuathung; Nattharinee Kongta; Ratchanon Inpan; Naruemon Suyayai; Nut Koonrungsesomboon
作者单位1. Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 2. Clinical Research Center for Food and Herbal Product Trials and Development (CR-FAH), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 3. School of Health Science, Mae Fah Luang University, Chiang Rai, Thailand; 4. Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 5. Pharmacoepidemiology and Statistics Research Center, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; 6. Office of Research Administration, Chiang Mai University, Chiang Mai, Thailand; 7. Transplant and Dialysis Unit, Medical Nursing Division, Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, Thailand; 8. Center of Multidisciplinary Technology for Advanced Medicine (CMUTEAM), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Understanding public perspectives on direct-to-consumer pharmacogenomic testing in the UK: a qualitative study
作者Amy Mathieson; Lisa Brunton; Stephanie Gillibrand; Ramona Moldovan; John H. McDermott
作者单位1. Centre for Primary Care and Health Services Research, University of Manchester, Greater Manchester, UK; 2. Division of Evolution & Genomic Sciences, University of Manchester, Greater Manchester, UK; 3. Manchester Centre for Genomic Medicine, Saint Mary’s Hospital, Manchester, Greater Manchester, UK; 4. Department of Psychology, Babeș-Bolyai University, Cluj-Napoca, Romania
Toxicity related to immunotherapy in urothelial cancer: Tumour genetic risk variants
作者JM Rodríguez-Piñas; A. Romero-Lorca; A. Novillo; M. Gaibar; M. Rubio; B. Antón-Pascual; S. Hernando; I. Alemany; FI Camacho; M. Cavanagh; M. Boiza; D. Marrupe; AM Martín; R. Khedaoui; A. Fernández-Santander
作者单位1. Department of Medicine, Faculty of Medicine, Health and Sports. Universidad Europea de Madrid, Madrid, Spain; 2. Human Genetic Variability Group, Hospital La Paz Institute for Health Research–IdiPAZ (La Paz University Hospital–Universidad Autónoma de Madrid–Getafe University Hospital–Universidad Europea de Madrid), Madrid, Spain; 3. Department of Cell Biology, Faculty of Medicine, Complutense University, Madrid, Spain; 4. Facultad HM de Ciencias de la Salud, Universidad Camilo José Cela, Instituto de Investigación Sanitaria HMHospitales, Madrid, Spain; 5. Department of Medical Oncology, Hospital Universitario Ramon y Cajal, Madrid, Spain; 6. Department of Medical Oncology, Hospital Universitario Fundación Alcorcón, Madrid, Spain; 7. Department of Pathological Anatomy, Hospital Universitario Fundación Alcorcón, Madrid, Spain; 8. Department of Pathological Anatomy, Hospital Universitario de Getafe, Madrid, Spain; 9. Department of Medical Oncology, Hospital Universitario de Getafe, Madrid, Spain; 10. Department of Pathological Anatomy, Hospital Universitario de Móstoles, Madrid, Spain; 11. Department of Medical Oncology, Hospital Universitario de Móstoles, Madrid, Spain; 12. Department of Medical Oncology, Hospital Universitario de Fuenlabrada, Madrid, Spain; 13. Department of Pathological Anatomy, Hospital Universitario de Fuenlabrada, Madrid, Spain
The association of ABCB1, CYP2C19 and CYP2C9 combined activity with clopidogrel resistance in patients with recurrent ischemic stroke
作者Birgit Deiman; Mike Hermans; Maarten de Rijk; Anne Bras; Volkher Scharnhorst
作者单位1. Catharina Hospital Eindhoven, Department of Clinical Chemistry, Eindhoven, the Netherlands; 2. Catharina Hospital Eindhoven, Department of Neurology, Eindhoven, the Netherlands
Cost-effectiveness of genome-guided statin treatment for hypercholesterolemia
作者Margarita-Ioanna Koufaki; Korina Tzerefou; Achilleas Tyrovolas; Vladimir Gasic; Vassilios Fragoulakis; Christina Mitropoulou
作者单位1. University of Patras, School of Health Sciences, Department of Pharmacy, Laboratory of Pharmacogenomics and Individualized Therapy, Patras, Greece; 2. The Golden Helix Foundation, London, UK; 3. Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Republic of Serbia; 4. United Arab Emirates University, College of Medicine and Health Sciences, Department of Genetics and Genomics, Al-Ain, UAE
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