医学
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Real-world pharmacogenomics-guided antihypertensive treatment response in clinical practice underrepresented population: implications for precision prescribing and medication safety
作者Nawal Alsubaie; Muhammad Ilyas; Zafar Ali Shah; Ammena Y. Binsaleh; Amani S. Alrossies; Fahad A Almazyad
作者单位1. Department of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia; 2. Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, USA; 3. Department of Agricultural Chemistry & Biochemistry, Faculty of Nutrition Sciences, The University of Agriculture, Peshawar, Pakistan; 4. Department of Family Medicine, King Abdullah bin Abdulaziz University Hospital, Riyadh, Saudi Arabia
Clobazam in pediatric drug-resistant epilepsy: from pharmacology to clinical practice
作者Jun Wan; Yupeng Yu; Xu Liu; Minling Zeng; Xiong Xie; Tianling Deng; Mingyu Zhao; Xiangyu Wang
作者单位1. Department of Pharmacy, Gezhouba Central Hospital of Sinopharm, The Third Clinical Medical College of China Three Gorges University, Yichang, China; 2. Yichang Humanwell Pharmaceutical Co., Ltd, Yichang, China; 3. Department of Neurology, Gezhouba Central Hospital of Sinopharm, The Third Clinical Medical College of China Three Gorges University, Yichang, China; 4. Department of Pediatrics, Gezhouba Central Hospital of Sinopharm, The Third Clinical Medical College of China Three Gorges University, Yichang, China; 5. Department of Geriatrics, Gezhouba Central Hospital of Sinopharm, The Third Clinical Medical College of China Three Gorges University, Yichang, China
Association between body mass index and serum concentrations of olanzapine and selective serotonin reuptake inhibitors in patients with eating disorders
作者Vilde Hersleth; Olav Spigset; Siri Weider; Elise Koch; Ole A. Andreassen; Stian Lydersen; Katrine Kveli Fjukstad
作者单位1. Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; 2. Department of Clinical Pharmacology, St. Olav University Hospital, Trondheim, Norway; 3. Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway; 4. Department of Psychology, Faculty of Social and Educational Sciences, Norwegian University of Science and Technology, Trondheim, Norway; 5. Eating Disorder Unit, Department of Psychiatry, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway; 6. Centre for Precision Psychiatry, Division of Mental Health and Addiction, Institute of Clinical Medicine, Oslo University Hospital, University of Oslo, Oslo, Norway; 7. Center for Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway; 8. KG Jebsen Centre for Neurodevelopmental Disorders, University of Oslo and Oslo University Hospital, Oslo, Norway; 9. Department of Mental Health, Faculty of Medicine and Health Sciences, Regional Centre for Child and Youth Mental Health and Child Welfare, Norwegian University of Science and Technology, Trondheim, Norway; 10. Department of Psychiatry, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway
Recent research progress on the mechanisms of clopidogrel resistance
作者Chunrong Wu; Xinyi Huang; Guoliang Zhu; Qing Cao; Yali Yang; Hewei Li; Yali Hu; Yapeng Lin; Junli Hao; Kejie Chen; Lingling Wang; Jiangmin Li; Quandan Tan; Jie Yang
作者单位1. School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China; 2. School of Biomedical Sciences and Technology, Chengdu Medical College, Chengdu, China; 3. Department of Neurology, Sichuan Provincial People’s Hospital, School of Medicine,University of Electronic Science and Technology of China, Chengdu, China; 4. Department of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, China; 5. School of Clinical Medicine, North Sichuan Medical College, Nanchong, China; 6. School of Clinical Medicine, Chengdu Medical College, Chengdu, China; 7. Department of Neurology, The First Affiliated Hospital of Chengdu Medical College, Chengdu, China; 8. School of Public Health, Chengdu Medical College, Chengdu, China; 9. School of Social Work and Health Management, Xihua University, Chengdu, China; 10. Department of Neurology, Bazhong Central Hospital, Bazhong, China
A review of seamless phase I/II trial designs towards oncology dose optimization with examples of clinical pharmacology considerations in early drug development
作者Yoko Franchetti; Adetayo Kasim; Laurence Collette; Pingping Ni
作者单位1. GSK, Collegeville, USA; 2. GSK, London, UK; 3. GSK, Wavre, Belgium
Comparative efficacy and safety of pharmacokinetically guided and body surface area–based 5-fluorouracil dosing in colorectal cancer: a systematic review and meta-analysis
作者Maryam Saqib; Wajahat Mirza; Syeda Tahira Zaidi; Abdullah Farooq; Mubashra Aslam; Sundas Rauf; Ahmed Al-Emam
作者单位1. King Edward Medical University, Lahore, Pakistan; 2. Shifa College of Medicine, Shifa Tameer-e-Millat University, Islamabad, Pakistan; 3. Department of Medicine, Combined Military Hospital (CMH), Lahore, Pakistan; 4. CMH Multan Institute of Medical Sciences, Multan, Pakistan; 5. Peshawar Medical College, Peshawar, Pakistan; 6. Department of Pathology, College of Medicine, Ahmed Al-Emam, King Khalid University, Abha, Saudi Arabia
Prescription duration of benzodiazepines: a retrospective cohort study of prescription duration in primary care
作者Kevin Trimm; Maria-Teresa Moraga; Bärbel Knäuper; Elham Rahme; Emily Gibson McDonald; Robyn Tamblyn
作者单位1. Experimental Medicine, McGill University, Montreal, Canada; 2. Epidemiology, Biostatistics, Occupational Health, McGill University, Montreal, Canada; 3. Psychology, McGill University, Montreal, Canada; 4. General Internal Medicine, McGill University, Montreal, Canada; 5. Department of Medicine, Division of Clinical Epidemiology & Department of Epidemiology, Biostatistics, Occupational Health, McGill University, Montreal, Canada
Pharmacological interventions targeting cognition and related clinical outcomes in vascular dementia: a systematic review and meta-analysis of randomized controlled trials
作者Tianyu Cheng; Lin Zhang; Yizhou Zhang; Huazheng Liang; Junyan Wang; Gengzhen Chen; Yujia Huo
作者单位1. The School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; 2. Suzhou Industrial Park Monash Research Institute of Science and Technology, Monash University, Suzhou, China; 3. Monash University-Southeast University Joint Research Institute (Suzhou), Southeast University, Suzhou, China; 4. State Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China; 5. Centre for Pharmaceutical Regulatory Sciences, University of Macau, Macao, China; 6. Faculty of Health Sciences, University of Macau, Macao, China; 7. Centre for Smart Process Engineering, Great Bay University, Dongguan, China; 8. Centre for Simulation and Modelling of Particulate Systems, Southeast University-Monash University Joint Research Institute, Suzhou, China; 9. The People’s Hospital of Chenghai District, Shantou City, China
Electrocardiographic identification of drug effects: QT prolongation, arrhythmias, and clinical monitoring
作者Canan Akman; Asli Bahar Ucar; Mehmet Can Girgin; Busra Erdem; Gokhan Yilmaz; Resad Beyoglu; Ozgur Karcioglu
作者单位1. Department of Emergency Medicine, Canakkale Onsekiz Mart University, Canakkale, Türkiye; 2. Department of Emergency Medicine, Marmara University School of Medicine, Istanbul, Türkiye; 3. Department of Emergency Medicine, Istanbul Beykent University, Istanbul, Türkiye; 4. Department of Emergency Medicine, University of Health Sciences, Istanbul Education and Research Hospital, Istanbul, Türkiye; 5. Department of Emergency Medicine, Meram State Hospital, Konya, Türkiye; 6. Department of Emergency Medicine, Onyedi Eylul University, Bandırma Training and Research Hospital, Balıkesir, Türkiye
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