生物学
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Combining in vitro and in silico approaches to model neural tube patterning and isthmic organizer formation
作者Fredrik Bertilsson; Alexander Degener; Paulina Ibek; Gaurav Singh Rathore; Emil Andersson; Pedro Rifes; Agnete Kirkeby; Victor Olariu
作者单位1. Computational Science for Health and Environment, Department of Earth and Environmental Sciences, Lund University, Lund, Sweden; 2. Department of Experimental Medical Science, Lund University, Lund, Sweden; 3. Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark; 4. Developmental and Regenerative Neurobiology, Department of Experimental Medical Science, Lund University, Lund, Sweden; 5. Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, Lund, Sweden
Bulk transcriptomics of peripheral blood mononuclear cells delineates systems-level immune dysregulation in pediatric dengue infection
作者Abdul R. Anshad; Muthuvel Atchaya; Amudhan Murugesan; Suvaiyarasan Suvaithenamudhan; Shanmugam Saravanan; Sivadoss Raju; Cecilia Svanberg; Marie Larsson; Esaki M. Shankar
作者单位1. Infection and Inflammation, Department of Biotechnology, Central University of Tamil Nadu, Thiruvarur, India; 2. Department of Microbiology, The Government Theni Medical College and Hospital, Theni, India; 3. School of Biosciences and Bioengineering, D. Y. Patil International University, Pune, India; 4. Dental Research Cell , Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pune, India; 5. State Public Health Laboratory, Directorate of Public Health and Preventive Medicine, DMS Campus, Chennai, India; 6. Molecular Medicine and Virology, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden
Metabolic set theory: a generalized model of microbial interactions
作者Jyoti Jyoti; Hannah Zoller; Wolfgang zu Castell; Marc-Thorsten Hütt
作者单位1. School of Science Constructor University Bremen, Bremen, Germany; 2. SRC Stockholm Resilience Centre, Stockholm, Sweden; 3. Department Geoinformation, GFZ Helmholtz Centre for Geosciences, Telegrafenberg, Potsdam, Germany; 4. Department of Statistics, Ludwig-Maximilians-University Munich, München, Germany
A minimal mechanically consistent model of smoothly dividing disk-shaped cells
作者Lukas Hupe; Yoav G. Pollack; Jonas Isensee; Aboutaleb Amiri; Ramin Golestanian; Philip Bittihn
作者单位1. Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany; 2. Institute for the Dynamics of Complex Systems, Göttingen University, Göttingen, Germany; 3. Max Planck Institute for the Physics of Complex Systems, Dresden, Germany; 4. Carl Zeiss, Oberkochen, Germany; 5. Rudolf Peierls Centre for Theoretical Physics, University of Oxford, Oxford, UK
Pathway-centric visualization of cell-cell communication in single-cell transcriptomics data
作者Sidrah Maryam; Martin Manolov; Rafael Kramann; Sikander Hayat
作者单位1. Department of Medicine 2, Uniklinik, Aachen, Germany; 2. Institute for Computational Genomics, Uniklinik, Aachen, Germany; 3. Cardiovascular Research Institute and Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA; 4. Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, New York, USA
Longitudinal spatial neutrophil profiling during ACT in murine melanoma reveals distinct lymph node infiltration patterns
作者Gemma van der Voort; Maike Effern; Michelle C. R. Yong; Lukas Kiwitz; Roberta Turiello; Sonia Leonardelli; Susanna Ng; Dillon Corvino; Tobias Bald; Nicole Glodde; Kevin Thurley; Jan Hasenauer; Michael Hölzel
作者单位1. Institute for Experimental Oncology, University Hospital Bonn, Bonn, Germany; 2. Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany; 3. Bonn Center for Mathematical Life Sciences, University of Bonn, Bonn, Germany
Prediction variability in physiologically based pharmacokinetic modeling of tissue disposition under deep uncertainty
作者Mustafa Farahat; D. T. Flaherty; Zachary R. Fox; Belinda S. Akpa
作者单位1. Department of Chemical and Biomolecular Engineering, University of Tennessee-Knoxville, Knoxville, USA; 2. Computational Sciences and Engineering Division, Oak Ridge National Laboratory, Oak Ridge, USA; 3. National Institute for Modeling Biological Systems, Knoxville, USA; 4. Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, USA
A fundamental trade-off among noise suppression, response sensitivity and speed in biological feedback networks
作者Ka Kit Kong; Feng Liu
作者单位1. School of Psychological and Cognitive Sciences, Peking University, Beijing, China; 2. The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics, Peking University, Beijing, China; 3. Key Laboratory of Hebei Province for Molecular Biophysics, Institute of Biophysics, School of Health Science & Biomedical Engineering, Hebei University of Technology, Tianjin, China
Multiscale hyperbolic embedding reveals hierarchical structure in complex biological systems
作者Mingchen Yao; Anoop Praturu; Tatyana O. Sharpee
作者单位1. Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, USA; 2. Department of Physics, University of California, San Diego, La Jolla, USA
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