医学
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Clinical Pharmacokinetics and Pharmacodynamics of the IL-1 Receptor Antagonist Anakinra: A Systematic Review
作者Jia Li; Megan Clark; David K. Metz; Marcel F. Nold; Carl M. J. Kirkpatrick
作者单位1. Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Australia; 2. Monash Children’s Hospital, Melbourne, Australia; 3. Department of Paediatrics, Monash University, Melbourne, Australia; 4. Murdoch Children’s Research Institute, Melbourne, Australia; 5. Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Australia
Informing Sampling Design for Lung Distribution Studies Using a Pulmonary Population Minimal PBPK Model
作者Haini Wen; Muhammad Waqas Sadiq; Markus Fridén; Jens M. Hohlfeld; Lena E. Friberg; Elin M. Svensson
作者单位1. Department of Pharmacy, Uppsala University, Uppsala, Sweden; 2. Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Gothenburg, Sweden; 3. Global Product Development, AstraZeneca, Gothenburg, Sweden; 4. Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover, Germany; 5. German Center for Lung Research (DZL-BREATH), Hannover, Germany; 6. Department of Respiratory Medicine and Infectious Disease, Hannover Medical School, Hannover, Germany; 7. Department of Pharmacy, Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands
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