医学
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Tumor cell-derived exosomes mediating hsa_circ_0001739/lncRNA AC159540.1 facilitate liver metastasis in colorectal cancer
作者Cai-Feng Yue; Ju-Gao Chen; Zi-Yue Li; Lai-Sheng Li; Jie-Rong Chen; Hai-Xia Xie; Bin Zhang; Yun-Miao Guo
作者单位1. Department of Laboratory Medicine, Central People’s Hospital of Zhanjiang, Guangdong Medical University Zhanjiang Central Hospital, Zhanjiang, People’s Republic of China; 2. Department of Oncology, Shenzhen People’s Hospital, Second Clinical Medical College of Jinan University, First Affiliated Hospital of Southern University of Science and Technology, Shenzhen, People’s Republic of China; 3. Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China; 4. Department of Laboratory Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China; 5. Department of Laboratory Medicine, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, People’s Republic of China; 6. Department of Cardiovascular Diagnosis, Central People’s Hospital of Zhanjiang, Guangdong Medical University Zhanjiang Central Hospital, Zhanjiang, People’s Republic of China; 7. Zhanjiang Institute of Clinical Medicine, Central People’s Hospital of Zhanjiang, Guangdong Medical University Zhanjiang Central Hospital, Zhanjiang, People’s Republic of China
Urinary extracellular vesicles prevent di-(2-ethylhexyl) phthalate-induced hypospadias by facilitating epithelial–mesenchymal transition via PFN2 delivery
作者Shibo Zhu; Xiangliang Tang; Jin Zhang; Jinhua Hu; Xiaofeng Gao; Dian Li; Wei Jia
作者单位1. Department of Pediatric Urology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, People’s Republic of China
SUMOylation of RALY promotes vasculogenic mimicry in glioma cells via the FOXD1/DKK1 pathway
作者Shuo Cao; Di Wang; Ping Wang; Yunhui Liu; Weiwei Dong; Xuelei Ruan; Libo Liu; Yixue Xue; Tiange E; Hongda Lin; Xiaobai Liu
作者单位1. Key Laboratory of Neuro-Oncology in Liaoning Province, Shenyang, China; 2. Department of Oncology, Shengjing Hospital of China Medical University, Shenyang, China; 3. Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, China; 4. Liaoning Medical Surgery and Rehabilitation Robot Technology Engineering Research Center, Shenyang, China; 5. Department of Neurobiology, School of Life Sciences, China Medical University, Shenyang, China
Recent advances in pluripotent stem cell-derived cardiac organoids and heart-on-chip applications for studying anti-cancer drug-induced cardiotoxicity
作者Silin Liu; Chongkai Fang; Chong Zhong; Jing Li; Qingzhong Xiao
作者单位1. The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China; 2. Centre for Clinical Pharmacology and Precision Medicine, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Heart Centre, Charterhouse Square, London, UK; 3. Guangdong Provincial Clinical Research Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China; 4. Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China; 5. Faculty of Biological Sciences, University of Leeds, Leeds, UK; 6. Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Institute of Cardiovascular Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
GPC3-IL7-CCL19-CAR-T primes immune microenvironment reconstitution for hepatocellular carcinoma therapy
作者Li-Li Lu; Shu-xiu Xiao; Zhi-yuan Lin; Jin-jin Bai; Wei Li; Zheng-qing Song; Yu-hong Zhou; Bin Lu; Wei-Zhong Wu
作者单位1. Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, China; 2. Clinical Center for Biotherapy, Zhongshan Hospital, Shanghai, China; 3. Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China; 4. Department of Medical Oncology, Fudan University, Shanghai, China; 5. Department of Biochemical Pharmacy School of Pharmacy, Naval Medical University, Shanghai, China
NRF2 is essential for iron-overload stimulated osteoclast differentiation through regulation of redox and iron homeostasis
作者Jian Zhang; Lingyan Zhang; Gang Yao; Hai Zhao; Shuguang Wu
作者单位1. Institute of Laboratory Animal Science, Guizhou University of Traditional Chinese Medicine, Huaxi University Town, Guiyang, China
Andrographolide attenuated MCT-induced HSOS via regulating NRF2-initiated mitochondrial biogenesis and antioxidant response
作者Zhenlin Huang; Zeqi Wu; Jingnan Zhang; Keke Wang; Qing Zhao; Minwei Chen; Shihao Yan; Qian Guo; Yun Ma; Lili Ji
作者单位1. The MOE Key Laboratory for Standardization of Chinese Medicines, Shanghai Key Laboratory of Compound Chinese Medicines, and The SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China; 2. Institute of Liver Studies, Department of Inflammation Biology, School of Immunology and Microbial Science, King’s College London, London, UK
circSSPO boosts growth of esophageal squamous cell carcinoma through upregulation of micrRNA-6820-5p-mediated KLK8 and PKD1 expression
作者Qianhua Luo; Junzheng Li; Haixiong Miao; Siman Su; Yun Chen; Chengcheng Xu; Chengkuan Zhao; Jianxiang Huang; Kai Ling; Chaoxian Lin; Hongfei Yan; Shuyao Zhang
作者单位1. Clinical Pharmacy Research Center, Shantou University Medical College, Shantou, People’s Republic of China; 2. Department of Pharmacy, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, People’s Republic of China; 3. Department of Otolaryngology-Head and Neck Surgery, Zhujiang Hospital of Southern Medical University, Guangzhou, China; 4. Department of Orthopaedics, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, People’s Republic of China; 5. Shantou Chaonan Minsheng Hospital, Shantou, People’s Republic of China; 6. Department of Pathology, Cancer Hospital of Shantou University Medical College, Shantou, People’s Republic of China
Imatinib and M351-0056 enhance the function of VISTA and ameliorate the development of SLE via IFN-I and noncanonical NF-κB pathway
作者Lu Yang; Tingting Zhang; Penglu Wang; Wenting Chen; Wanmei Liu; Xiaoyu He; Yuxin Zhang; Shasha Jin; Zhijie Luo; Zunjian Zhang; Xinzhi Wang; Jun Liu
作者单位1. New Drug Screening Center, China Pharmaceutical University, Nanjing, China
Single-cell RNA sequencing reveals differences between force application and bearing in ankle cartilage
作者Junjie Wang; Zewen Sun; Chenghao Yu; Haibo Zhao; Mingyue Yan; Shenjie Sun; Xu Han; Tingting Jiang; Tianrui Wang; Tengbo Yu; Yingze Zhang
作者单位1. Qingdao Medical College, Qingdao University, Qingdao, China; 2. Department of Orthopaedic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China; 3. Department of Emergency, Qingdao Municipal Hospital, Qingdao, China; 4. LC-Bio Technologies, Co., Ltd., Hangzhou, China; 5. Department of Orthopaedic Surgery, Qingdao Hospital of the University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, China
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