医学
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Anti-inflammatory phytochemicals from medicinal herbs based on senoinflammation schema for healthy aging
作者Radha Arulkumar; Sang Gyun Noh; Hee Jin Jung; Seungwoo Kim; Mi Kyung Kim; Eric Lim; Arulkumar Nagappan; Jin Hwan Lim; Hae Young Chung
作者单位1. Interdisciplinary Research Program of Bioinformatics and Longevity Science, Pusan National University, Busan, Republic of Korea; 2. PG & Research Department of Biotechnology & Bioinformatics Holy Cross College (Autonomous) (Affiliated to Bharathidasan University), Tiruchirappalli, India; 3. Research Institute for Drug Development, Pusan National University, Busan, Republic of Korea; 4. Department of Pharmacy, College of Pharmacy, Pusan National University, Busan, Republic of Korea; 5. Division of Nutritional Sciences, Cornell University College of Human Ecology, Ithaca, USA; 6. Department of Pathology, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India; 7. Department of Environmental and Occupational Health Program in Public, Health University of California, Irvine, USA
Dexmedetomidine attenuates sepsis-associated NET formation and Th17 polarization through α2-adrenergic receptor-associated regulation of hepatic HPD
作者Haihong Fang; Shuang Wang; Zhuo Ma; Youming Pei; Ying Chen
作者单位1. Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, China; 2. Guangdong Provincial Key Laboratory of Precision Anesthesia and Perioperative Organ Protection, Guangzhou, China
cGAS–STING signaling in aging and age-related diseases: therapeutic promise and precaution
作者Yingying Xu; Weidong Wu; Yifan Guo; Wenhong Wang; Jingsheng Zhu; Weihua Xiao
作者单位1. Department of Physical Education, Henan Sport University, Zhengzhou, China; 2. Department of Sport, Henan Sport University, Zhengzhou, China; 3. School of Elderly Care Services and Management, Nanjing University of Chinese Medicine, Nanjing, China; 4. School of Physical Education and Health, Zunyi Medical University, Zunyi, China; 5. Shanghai Key Lab of Human Performance, Shanghai University of Sport, Shanghai, China
A novel Skp2 inhibitor triggers pyroptosis in leukemia via phospholipid metabolism disorder and mitochondria-associated endoplasmic reticulum membranes
作者Xiaolong Tian; Jiarun Li; Guancui Yang; Peijie Jiang; Xueqing Yang; Shijie Yang; Xi Zhang; Jinyi Liu
作者单位1. State Key Laboratory of Trauma and Chemical Poisoning, Military Key Clinical Specialty, Chongqing Key Clinical Specialty, Chongqing Key Laboratory of Hematology and Microenvironment, Medical Center of Hematology, Second Affiliated Hospital, Army Medical University, Chongqing, China; 2. School of Medicine, Chongqing University, Chongqing, China; 3. Department of Hematology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China; 4. Jinfeng Laboratory, Chongqing, China
Integrative multi-omics analyses reveal nuclear noncoding RNA-mediated regulatory landscape in Alzheimer’s disease
作者Sumin Yang; Sung-Hyun Kim; Jeonghyeon Choi; Yeyoung Lee; Jeehye Jung; Jae-Yeol Joo
作者单位1. Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Republic of Korea
Tumor organoid platform design for drug response modeling: culture architecture, microenvironmental complexity, and AI-assisted readouts
作者Eun Ah Shin; Won-Cheol Jeong; Ye-Won Kim; Ji Won Kim; Miso Park
作者单位1. College of Pharmacy, Kangwon National University, Chuncheon, Republic of Korea; 2. College of Pharmacy, Jeju Research Institute of Pharmaceutical Sciences, Jeju National University, Jeju-do, Republic of Korea
Acetylation-dependent regulation of FOX–Ku interaction by GCN5–SIRT1 axis controls non-homologous end-joining DNA repair
作者Yongyang Luo; Kangseok Lee; Jeehyeon Bae
作者单位1. Department of Life Science, Chung-Ang University, Seoul, South Korea; 2. R&D Institute, NES Biotechnology, Seoul, South Korea; 3. School of Pharmacy, Chung-Ang University, Seoul, South Korea
Liver organoids for chemical risk assessment: biological fidelity, standardization, and context-of-use frameworks
作者Yongbo Shin; Hye-Ran Moon; You Mie Lee; Myung Jin Son
作者单位1. Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea; 2. Department of Advanced Bioconvergence, Korea University of Science & Technology (UST), Daejeon, Republic of Korea; 3. School of Integrative Engineering, Chung-Ang University, Seoul, Republic of Korea; 4. Vessel-Organ Interaction Research Center VOICE (MRC), College of Pharmacy, Kyungpook National University, Daegu, Republic of Korea
eHsp90α enhances breast cancer cell invasion by activating the LRP1-EGFR/AKT-twist/snail signaling axis in cancer-associated fibroblasts
作者Su Jin Cho; Se-Hee Yoon; Chang Gyo Park; Hoi Young Lee
作者单位1. Department of Pharmacology, College of Medicine, Konyang University, Daejeon, Republic of Korea; 2. Division of Nephrology and Department of Internal Medicine, Myunggok Medical Research Institute, College of Medicine, Konyang University, Daejeon, Republic of Korea
Therapeutic potential of glycyrrhizic acid in inflammation-related diseases: from HMGB1-oriented molecular insights to preclinical application
作者Yicheng Hu; Jiani Hou; Yifeng Cai; Chaoran Ni; Zhewen Xing; Jingtian Li; Zan Zhou; Guangtao Xu; Xiansi Zeng; Jinjing Jia; Li Li
作者单位1. Research Center of Neuroscience, Jiaxing University Medical College, Jiaxing, China; 2. Judicial Expertise Center, Jiaxing University, Jiaxing, China; 3. Department of Biochemistry and Molecular Biology, Jiaxing University Medical College, Jiaxing, China; 4. Department of Physiology, Jiaxing University Medical College, Jiaxing, China
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