NATURE MEDICINE

作者Ida Aronchik; Sumit Kar; Yongxian Zhuang; Ethan Ahler; Lick Pui Lai; Vidya Seshadri; Yu Chi Yang; Ashenafi Bulle; Marie Menard; Biswadeep Nayak; Mark P. Labrecque; Julien Dilly; Eejung Kim; Lingyan Jiang; Jason Yano; Urszula N. Wasko; Ciara Helland; Sean Bredeson; Brett Garrick; Yevgeniy Gindin; Brad Sickler; Xing Wei; Kyle Seamon; Jingjing Jiang; Kian-Huat Lim; Matthew Holderfield; Elsa Quintana; Aparna Hegde; Zeena Salman; Alexander Starodub; Alexander Spira; Wungki Park; David S. Hong; Minal Barve; Meredith Pelster; David Sommerhalder; Salman R. Punekar; Ignacio Garrido-Laguna; Brian M. Wolpin; Anirban Maitra; W. Clay Gustafson; Steve Kelsey; Jacqueline A. M. Smith; Kevin K. Lin; Andrew J. Aguirre; Mallika Singh

作者单位1. Revolution Medicines, Redwood City, USA; 2. Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, USA; 3. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USA; 4. Harvard Medical School, Boston, USA; 5. Broad Institute of MIT and Harvard, Cambridge, USA; 6. The Christ Hospital Health Network, Parkview Physician Group - Parkview Cancer Institute, Cincinnati, USA; 7. NEXT Oncology Virginia, Virginia Cancer Specialists Research Institute, Fairfax, USA; 8. Memorial Sloan Kettering Cancer Center, David M. Rubenstein Center for Pancreatic Cancer Research, Weill Cornell Medical College, New York, USA; 9. The University of Texas MD Anderson Cancer Center, Department of Investigational Cancer Therapeutics, Houston, USA; 10. University of Utah, Huntsman Cancer Institute, Salt Lake City, USA; 11. Mary Crowley Cancer Research, Texas Oncology, Dallas, USA; 12. Sarah Cannon Research Institute, Nashville, USA; 13. NEXT Oncology, San Antonio, USA; 14. NYU Langone Health, Perlmutter Cancer Center, New York, USA

作者Yiying Wang; Jennifer L. Sargent; Chantal Mathieu; Elsa Vazquez-Arreola; Leigh Perreault; Ruth J. F. Loos; Lee-Ling Lim; Leontine Sandforth; Robert L. Hanson; Stephanie Kullmann; Julia Sbierski-Kind; Sara Y. Brucker; Martin Hrabé de Angelis; Fabian Theiss; Andrea Icks; Damon Mohebbi; Norbert Stefan; Viswanathan Mohan; Tiange Wang; Hubert Preissl; Michael Bergman; Jaakko Tuomilehto; Marie-France Hivert; Paul W. Franks; Andreas L. Birkenfeld

作者单位1. Department of Internal Medicine IV—Diabetology, Endocrinology, Nephrology, University Hospital Tübingen, University of Tübingen, Tübingen, Germany; 2. Institute for Diabetes Research and Metabolic Diseases, Helmholtz Munich, Tübingen, Germany; 3. German Center for Diabetes Research, Neuherberg, Germany; 4. School of Public Health, Imperial College London, London, UK; 5. Heidelberg Institute of Global Health, University of Heidelberg, Heidelberg, Germany; 6. Department of Endocrinology, UZ Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium; 7. National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, USA; 8. Division of Endocrinology, Metabolism and Diabetes, University of Colorado School of Medicine, Aurora, USA; 9. Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; 10. The Charles Bronfman Institute for Personalized Medicine, Department of AI in Health, Icahn School of Medicine at Mount Sinai, New York, USA; 11. Department of Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia; 12. The M3 Research Center, University Hospital Tübingen, University of Tübingen, Tübingen, Germany; 13. Department of Women’s Health, University Hospital Tübingen, University of Tübingen, Tübingen, Germany; 14. Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Neuherberg, Germany; 15. Chair of Experimental Genetics, TUM School of Life Sciences, Technische Universität München, Freising, Germany; 16. Helmholtz Munich, Munich, Germany; 17. Institute for Health Services Research and Health Economics, German Diabetes Center, Leibniz Center for Diabetes Research, Heinrich Heine University Düsseldorf, Düsseldorf, Germany; 18. Institute for Health Services Research and Health Economics, Centre for Health and Society, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany; 19. Institute of General Practice, Centre for Health and Society, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany; 20. Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK; 21. Madras Diabetes Research Foundation (Indian Council of Medical Research Collaborating Centre of Excellence)–Dr. Mohan’s Diabetes Specialties Centre (International Diabetes Federation Centre of Excellence in Diabetes Care), Chennai, India; 22. National Clinical Research Center for Endocrine and Metabolic Diseases (Shanghai), Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; 23. NYU Grossman School of Medicine, Department of Medicine, Holman Division of Endocrinology, Diabetes and Metabolism, New York, USA; 24. Department of Public Health, University of Helsinki, Helsinki, Finland; 25. Department of Population Medicine at Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, USA; 26. Diabetes Unit, Massachusetts General Hospital, Boston, USA; 27. Genetic & Molecular Epidemiology Unit, Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Helsingborg, Sweden; 28. Precision Healthcare University Research Institute, Queen Mary University of London, London, UK; 29. Diabetes and Obesity Theme, School of Cardiovascular and Metabolic Medicine and Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, UK

作者Xuhai ‘Orson’ Xu; Haoyu Hu; Haoran Zhang; Will Ke Wang; Reina Wang; Luis R. Soenksen; Omar Badri; Sheharbano Jafry; Elise Burger; Lotanna Nwandu; Apoorva Mehta; Erik P. Duhaime; Asif Qasim; Hause Lin; Janis Karleen Pereira; Jonathan Hershon; Paulius Mui; Alejandro A. Gru; Noémie Elhadad; Lena Mamykina; Matthew Groh; Philipp Tschandl; Roxana Daneshjou; Marzyeh Ghassemi

作者单位1. Columbia University, New York, USA; 2. Cornell University, Ithaca, USA; 3. Massachusetts Institute of Technology, Cambridge, USA; 4. Johns Hopkins University, Baltimore, USA; 5. Northeast Dermatology Associates, Beverly, USA; 6. Stanford University, Stanford, USA; 7. University of Utah, Salt Lake City, USA; 8. OSF HealthCare, Peoria, USA; 9. Centaur.AI, Boston, USA; 10. MedShr, London, UK; 11. Pathway, Montréal, Canada; 12. X=Primary Care, Cambridge, USA; 13. Northwestern University, Evanston, USA; 14. Medical University of Vienna, Vienna, Austria

作者F. Mosele; A. Peltier; Y. Ozaki; A. Detappe; J. C. Soria; F. André

作者单位1. Drug Development Department (DITEP), Gustave Roussy, Villejuif, France; 2. IHU PRISM National PRecISion Medicine Center in Oncology, Gustave Roussy, Villejuif, France; 3. INSERM U981, Gustave Roussy, Paris, France; 4. Department of Breast Medical Oncology, Breast Oncology Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan; 5. Université Paris-Saclay, Gustave Roussy, Inserm U1363, Biothérapies Innovantes, Villejuif, France; 6. Institut Strauss, Strasbourg, France; 7. Equipe Labellisée Ligue Contre le Cancer, Paris, France; 8. Strasbourg Drug Discovery and Development Institute (IMS), Strasbourg, France; 9. Université Paris-Saclay, Gif-Sur-Yvette, France; 10. Amgen, R&D, Global Oncology Development, Thousand Oaks, USA; 11. Department of Medical Oncology, Gustave Roussy, Villejuif, France

作者Isabel Kerrebijn; Gyda Bjornsdottir; Keon Arbabi; Lea Urpa; Hele Haapaniemi; Gudmar Thorleifsson; Lilja Stefansdottir; Stephan Frangakis; Jesse Valliere; Lovemore Kunorozva; Erik Abner; Caleb Ji; Markus Kangur; Bitten Aagaard; Henning Bliddal; Søren Brunak; Mie T. Bruun; Maria Didriksen; Christian Erikstrup; Sarah Finer; Arni J. Geirsson; Daniel F. Gudbjartsson; Thomas F. Hansen; David van Heel; Ingileif Jonsdottir; Stacey Knight; Kirk U. Knowlton; Christina Mikkelsen; Lincoln D. Nadauld; Thorunn A. Olafsdottir; Sisse R. Ostrowski; Ole B. V. Pedersen; Saedis Saevarsdottir; Astros T. Skuladottir; Erik Sørensen; Hreinn Stefansson; Patrick Sulem; Olafur A. Sveinsson; Gudny E. Thorlacius; Unnur Thorsteinsdottir; Henrik Ullum; Arnor Vikingsson; Thomas M. Werge; Richa Saxena; Kari Stefansson; Chad M. Brummett; Bente Glintborg; Daniel J. Clauw; Thorgeir E. Thorgeirsson; Frances M. K. Williams; Nasa Sinnott-Armstrong; Hanna M. Ollila; Michael Wainberg

作者单位1. Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada; 2. Institute of Medical Science, University of Toronto, Toronto, Canada; 3. Amgen deCODE Genetics, Reykjavik, Iceland; 4. Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health, Toronto, Canada; 5. Stanley Center for Psychiatric Research, Broad Institute, Cambridge, USA; 6. Center for Genomic Medicine, Massachusetts General Hospital, Boston, USA; 7. Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland; 8. Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, USA; 9. Molecular and Population Genetics Program, Broad Institute, Cambridge, USA; 10. Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, USA; 11. Institute of Genomics, Estonian Genome Center, University of Tartu, Tartu, Estonia; 12. Department of Computer Science, University of Toronto, Toronto, Canada; 13. Department of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark; 14. The Parker Institute, Copenhagen University Hospital Bispebjerg Frederiksberg, Copenhagen, Denmark; 15. Department of Public Health, University of Copenhagen, Copenhagen, Denmark; 16. Novo Nordisk Center for Protein Research, University of Copenhagen, Copenhagen, Denmark; 17. Clinical Immunology Research Unit, Department of Clinical Immunology, Odense University Hospital, Odense, Denmark; 18. Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; 19. Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark; 20. Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; 21. Wolfson Institute of Population Health, Queen Mary University of London, London, UK; 22. Department of Rheumatology, Landspitali University Hospital, Reykjavik, Iceland; 23. Neurogenomics, Translational Research Centre, Copenhagen University Hospital, Glostrup, Denmark; 24. Danish Multiple Sclerosis Center, Copenhagen University Hospital, Glostrup, Denmark; 25. Danish Headache Center, Copenhagen University Hospital, Glostrup, Denmark; 26. Blizard Institute, Queen Mary University of London, London, UK; 27. Precision Healthcare University Research Institute, Queen Mary University of London, London, UK; 28. Intermountain Medical Center, Intermountain Heart Institute, Salt Lake City, USA; 29. Intermountain Healthcare, Saint George, USA; 30. School of Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland; 31. Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; 32. Department of Clinical Immunology, Zealand University Hospital, Koege, Denmark; 33. Department of Neurology, Landspitali University Hospital, Reykjavik, Iceland; 34. Statens Serum Institut, Copenhagen, Denmark; 35. Institute of Biological Psychiatry, Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark; 36. Department of Anesthesiology, Mass General Brigham, Harvard Medical School, Boston, USA; 37. Opioid Research Institute, Office for the Vice President for Research, University of Michigan, Ann Arbor, USA; 38. Overdose Prevention Engagement Network, Institute for Healthcare Policy and Innovation, Michigan Medicine, Ann Arbor, USA; 39. Copenhagen Center for Arthritis Research (COPECARE) and DANBIO, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark; 40. Chronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, USA; 41. Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King’s College London, London, UK; 42. Herbold Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, USA; 43. Department of Genome Sciences, University of Washington, Seattle, USA; 44. Brotman Baty Institute, University of Washington, Seattle, USA; 45. Center for Synthetic Biology, University of Washington, Seattle, USA; 46. Center for One Health Research, University of Washington, Seattle, USA; 47. Department of Psychiatry, University of Toronto, Toronto, Canada; 48. Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada

作者STIMULATE-ICP Consortium

作者单位1. University College London, London, UK; 2. Lancashire Clinical Trials Unit, University of Lancashire, Preston, UK; 3. The Francis Crick Institute, London, UK; 4. University College London Hospitals NHS Trust, London, UK; 5. Tameside and Glossop Integrated Care NHS Foundation Trust, Tameside General Hospital, Lancashire, UK; 6. Royal Free NHS Foundation Trust, London, UK; 7. Sheffield Teaching Hospitals NHS Foundation Trust, Northern General Hospital, Sheffield, UK; 8. Perspectum Ltd, Oxford, UK; 9. Applied Health Research Hub, University of Lancashire, Preston, UK; 10. Patient and Public Representative, C/O Institute of Health Informatics, University College London, London, UK; 11. Hull University Teaching Hospitals NHS Foundation Trust, Hull Royal Infirmary, Hull, UK; 12. Derbyshire Community Health Services NHS Foundation Trust, Ash Green Learning Disability Centre, Chesterfield, UK; 13. Living With Ltd, Brighton, UK; 14. Department of Health Sciences, University of York, York, UK; 15. University of Liverpool, Liverpool, UK; 16. University of Exeter, Exeter, UK; 17. Reading Central Primary Care Network, Pembroke Surgery, Reading, UK; 18. University of Southampton, Southampton, UK; 19. University Hospitals Sussex NHS Foundation Trust, Worthing Hospital, Worthing, UK; 20. Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK; 21. NHS England, London, UK; 22. Livewell Southwest, Plymouth, UK; 23. Department for Work and Pensions, London, UK; 24. Barts Health NHS Trust, The Royal London Hospital, London, UK; 25. NHS Highlands, Inverness, UK; 26. University of Leicester, Leicester, UK; 27. The Princess Alexandra Hospital NHS Trust, Harlow, UK; 28. University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Leicester, UK; 29. University of Sussex, Brighton, UK; 30. University of Hull, Kingston upon Hull, UK; 31. Long Covid SOS, Aldridge, UK; 32. Department of Economics, The University of Auckland, Auckland, New Zealand; 33. Vauxhall Primary Care, Liverpool, UK; 34. Royal Devon and Exeter NHS Foundation Trust, Royal Devon and Exeter Hospital (Wonford), Exeter, UK

作者Shabir A. Madhi; Hasra Snaggs; Zahra Skogeby; Ye Feng; Shaun Barnabas; Jeffrey Baker; Lee Fairlie; Johannes Beeslaar; David Radley; Han-Qing Jiang; Natalie C. Silmon de Monerri; Raphael Simon; Lindsay McLaughlin; Michelle Gaylord; Julie Skinner; Iona Munjal; Annaliesa S. Anderson; Alejandra Gurtman

作者单位1. South African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; 2. Wits Infectious Diseases and Oncology Research Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; 3. Pfizer Vaccines, Pfizer Inc., Pearl River, USA; 4. Pfizer Vaccines, Pfizer Ltd, Marlow, UK; 5. Family Center for Research with Ubuntu, Department of Paediatrics and Child Health, Stellenbosch University, Stellenbosch, South Africa; 6. Clinical Research Prime, Idaho Falls, USA; 7. Wits RHI, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; 8. Pfizer Vaccines, Pfizer Inc., Collegeville, USA

作者Michael Pavlides; Yasaman Vali; Ferenc E. Mózes; Kristy Wonders; Salma Akhtar; Paul D. Hockings; Elizabeth Shumbayawonda; Kay Pepin; Isabel Fernandez-Lizaranzu; Diana Julie Leeming; Jeremy F. Cobbold; Michael E. D. Allison; Guruprasad P. Aithal; Manuel Romero-Gomez; Rocio Aller; Juan M. Pericàs; Jérôme Boursier; Salvatore Petta; Jörn M. Schattenberg; Mattias Ekstedt; Annalisa Berzigotti; Hannele Yki-Järvinen; Miljen Martic; Theresa Tuthill; Clifford A. Brass; Michael Kalutkiewicz; Rajarshi Banerjee; Richard L. Ehman; Moritz J. Schneider; Dina Tiniakos; Morten Karsdal; Jeremy Magnanensi; Céline Fournier-Poizat; Vlad Ratziu; Carla Yunis; Elisabetta Bugianesi; Stephen A. Harrison; Patrick M. Bossuyt; Quentin M. Anstee

作者单位1. Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; 2. Translational Gastroenterology and Liver Unit, University of Oxford, Oxford, UK; 3. Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust and the University of Oxford, Oxford, UK; 4. Department of Epidemiology and Data Science, Amsterdam Public Health, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands; 5. Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany; 6. Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK; 7. Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK; 8. Antaros Medical AB, Mölndal, Sweden; 9. Perspectum Ltd., Oxford, UK; 10. Resoundant Inc., Rochester, USA; 11. Instituto de Biomedicina de Sevilla, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain; 12. Hepatic and Digestive Diseases Networking Biomedical Research Centre (CIBERehd), Grupo de Física Interdisciplinar, Universidad de Sevilla, Sevilla, Spain; 13. Nordic Bioscience, Biomarkers & Research, Herlev, Denmark; 14. Liver Unit, Department of Medicine, Cambridge NIHR Biomedical Research Centre, Cambridge University NHS Foundation Trust, Cambridge, UK; 15. NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, UK; 16. Nottingham Digestive Diseases Centre, Translational Medical Sciences, School of Medicine, University of Nottingham, Nottingham, UK; 17. Digestive Diseases Unit, Hospital Universitario Virgen del Rocío, Sevilla, Spain; 18. Hepatic and Digestive Diseases Networking Biomedical Research Centre (CIBERehd), Instituto de Biomedicina de Sevilla, Universidad de Sevilla, Sevilla, Spain; 19. Department of Gastroenterology, Clinic University Hospital, Medical School, University of Valladolid, CIBERINFEC, Valladolid, Spain; 20. Liver Unit, Vall d’Hebron Institut de Recerca, Vall d’Hebron Barcelona Hospital, Universitat Autònoma de Barcelona, Centros de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBERehd), Barcelona, Spain; 21. HIFIH Laboratory, SFR ICAT 4208, Angers University, Angers, France; 22. Hepato-Gastroenterology and Digestive Oncology Department, Angers University Hospital, Angers, France; 23. Section of Gastroenterology and Hepatology, PROMISE, Palermo, Italy; 24. Department of Internal Medicine II, Saarland University Medical Center, Homburg, Germany; 25. Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; 26. Department for Visceral Medicine and Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; 27. Department of Biomedical Research, University of Bern, Bern, Switzerland; 28. Department of Medicine, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; 29. Minerva Foundation Institute for Medical Research, Helsinki, Finland; 30. Novartis Institutes for BioMedical Research, Basel, Switzerland; 31. Digital Sciences and Translational Imaging, Pfizer Inc., Cambridge, USA; 32. Resolution Therapeutics, London, UK; 33. Department of Radiology, Mayo Clinic, Rochester, USA; 34. Department of Pathology, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece; 35. Genfit S.A., Loos, France; 36. Echosens, Paris, France; 37. ICAN Institute for Cardiometabolism and Nutrition, INSERM UMRS 1138 CRC, Sorbonne Université, Paris, France; 38. Assistance-Publique Hôpitaux de Paris, INSERM UMRS 1138 CRC, Paris, France; 39. Research and Development, Pfizer Inc., Lake Mary, USA; 40. Department of Medical Sciences, University of Turin, Torino, Italy

作者Martina L. Porter; Antonio Martorell; Christopher J. Sayed; Falk G. Bechara; Hadar Lev-Tov; Jennifer L. Hsiao; John W. Frew; Ziad Reguiaï; Melinda J. Gooderham; Noah Goldfarb; Hessel H. van der Zee; Veronique del Marmol; Angelo V. Marzano; Benjamin D. Ehst; Lindsay S. Ackerman; Koremasa Hayama; Chenwei Tian; Jennifer Kelley; Huiling Zhen; Joslyn S. Kirby; Kurt Brown; Leandro L. Santos; Christos C. Zouboulis

作者单位1. Department of Dermatology, Harvard Medical School, Boston, USA; 2. Beth Israel Deaconess Medical Center, Boston, USA; 3. Inflammatory Diseases Unit, Department of Dermatology, Venereology and Surgery, Hospital de Manises, Valencia, Spain; 4. Department of Dermatology, University of North Carolina School of Medicine, Chapel Hill, USA; 5. ICH – International Center for Hidradenitis Suppurativa/Acne Inversa, Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, Germany; 6. Dr. Philip Frost Department of Dermatology and Cutaneous Surgery, University of Miami, Miami, USA; 7. Department of Dermatology, University of Southern California, Los Angeles, USA; 8. Laboratory of Translational Cutaneous Medicine, Ingham Institute for Applied Medical Research, Liverpool, Australia; 9. Department of Dermatology, Liverpool Hospital, Liverpool, Australia; 10. School of Clinical Medicine, University of New South Wales Sydney, Kensington, Australia; 11. Department of Dermatology, Polyclinique Courlancy-Bezannes, Reims-Bezannes, France; 12. Probity Medical Research, Waterloo, Canada; 13. SKiN Centre for Dermatology, Peterborough, Canada; 14. Queen’s University, Kingston, Canada; 15. Departments of Dermatology and Medicine, University of Minnesota, Minneapolis, USA; 16. Department of Dermatology, University of Minnesota Physicians, Minneapolis, USA; 17. Department of Dermatology, Erasmus Medical Center, Rotterdam, Netherlands; 18. Department of Dermatology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium; 19. Dermatology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy; 20. Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; 21. Oregon Medical Research Center, Portland, USA; 22. USA Medical Dermatology Specialists, US Dermatology Partners, Phoenix, USA; 23. Division of Cutaneous Science, Department of Dermatology, Nihon University School of Medicine, Itabashi City, Tokyo, Japan; 24. Incyte Corporation, Wilmington, USA; 25. Department of Dermatology, Venereology, and Immunology, Universitaetsklinikum Ruppin-Brandenburg, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Neuruppin, Germany

作者Adam D. Cohen; Joshua Richter; Suzanne Trudel; Alexander Lesokhin; Jacob P. Laubach; Sheeba K. Thomas; Simon J. Harrison; Luciano J. Costa; Andrew Spencer; Rafael Fonseca; Peter A. Forsberg; Jesus G. Berdeja; Rayan Kaedbey; Nizar J. Bahlis; Paula Rodriguez-Otero; Maria-Victoria Mateos; Tulika Tyagi; Divya Samineni; Wenyu Liu; Rin Nakamura; Voleak Choeurng; Chihunt Wong; James Cooper; Amrita Krishnan

作者单位1. Abramson Cancer Center and University of Pennsylvania, Philadelphia, USA; 2. Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA; 3. Princess Margaret Cancer Centre and University of Toronto, Toronto, Canada; 4. Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, USA; 5. Dana-Farber Cancer Institute, Boston, USA; 6. The University of Texas MD Anderson Cancer Center, Houston, USA; 7. Peter MacCallum Cancer Centre, Sir Peter MacCallum Department of Oncology, Melbourne University, and The Royal Melbourne Hospital, Melbourne, Australia; 8. O’Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, USA; 9. Alfred Health-Monash University, Melbourne, Australia; 10. Mayo Clinic in Arizona, Phoenix, USA; 11. University of Colorado School of Medicine, Aurora, USA; 12. Tennessee Oncology and Sarah Cannon Research Institute, Nashville, USA; 13. Jewish General Hospital, McGill University, Montreal, Canada; 14. Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Canada; 15. Clínica Universidad de Navarra, Pamplona, Spain; 16. Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Centro de Investigación del Cáncer (CIC) and Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Salamanca, Spain; 17. Genentech, Inc., South San Francisco, USA; 18. City of Hope Duarte, Duarte, USA