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10 篇有效样本 · 按发表日期由新到旧排列
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Advanced imaging of membrane contact sites
作者Riccardo Filadi; Ambra Bertocco; Michela Rossini; Paola Pizzo
作者单位1. Department of Biomedical Sciences, University of Padua, Padua, Italy; 2. Institute of Neuroscience, National Research Council, Padua, Italy; 3. Department of Biology, University of Padua, Padua, Italy
Targeting oncogenic FLT3 uncovers a ferroptosis vulnerability through selenocysteine recoding in acute myeloid leukaemia
作者Minhua Li; Yudan Zhu; Yuki Kageyama; Ken Furudate; Ayumi Kitano; Taotao Tan; Mengdie Feng; Jing Zhou; Tao Wang; Robert J. Taylor; Alexandra M. Stevens; Md. Abul Hassan Samee; Jeffrey A. Magee; Koichi Takahashi; Daisuke Nakada
作者单位1. Graduate Program in Development, Disease Models and Therapeutics, Baylor College of Medicine, Houston, USA; 2. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, USA; 3. Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, USA; 4. Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, USA; 5. Department of Integrative Physiology, Baylor College of Medicine, Houston, USA; 6. Graduate Program Quantitative and Computational Biosciences, Baylor College of Medicine, Houston, USA; 7. Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, USA; 8. Veterinary Integrative Biosciences, Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, USA; 9. Division of Pediatric Hematology/Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, USA; 10. Department of Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine, St. Louis, USA
Stromal cell senescence augments haematopoietic cell fitness in clonal haematopoiesis
作者Jayna J. Mistry; Kira A. Young; Anna Navarro Figueredo; Gibran Edun; Alicia G. Aguilar-Navarro; Patricia A. Colom Díaz; Maria Telpoukhovskaia; Inés Fernández Maestre; Sheng F. Cai; Katharina S. Götze; Anastasia N. Tikhonova; Ross L. Levine; Jennifer J. Trowbridge
作者单位1. The Jackson Laboratory, Bar Harbor, USA; 2. Department of Medicine III, School of Medicine and Health, Technical University of Munich, Munich, Germany; 3. University Health Network, Princess Margaret Cancer Centre, Toronto, Canada; 4. Memorial Sloan Kettering Cancer Center, Louis V. Gerstner Jr Graduate School of Biomedical Sciences, New York, USA; 5. Human Oncology and Pathogenesis Program, Center for Hematologic Malignancies and Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA; 6. Bavarian Cancer Research Center (BZKF), Munich, Germany; 7. Department of Medical Biophysics and Department of Immunology, University of Toronto, Toronto, Canada; 8. Ontario Institute for Cancer Research, Toronto, Canada
Cancer stem cells are hyper-responsive sensors of the tumour microenvironment and regulate metastasis dynamics through YAP/TAZ
作者Binwu Tang; Jacob Minin; Victoria M. Gonzalez; Zoya Z. Khan; Andrew R. Gaines; Yuval Raviv; Yu-an Yang; Christine P. Carney; Zachary G. Millman; Daniel Grun; Cristiana M. Pineda; Alina Sharma; Dominic Esposito; Hualong Yan; Jing Huang; Andy D. Tran; Michael Kruhlak; Howard H. Yang; Maxwell P. Lee; Lalage M. Wakefield
作者单位1. Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA; 2. Protein Expression Laboratory, Frederick National Laboratory for Cancer Research, Frederick, USA
Mapping mesenchymal diversity in the human small intestine and organoids
作者Kelli F. Johnson; Xiangning Dong; Yu-Hwai Tsai; Angeline Wu; Sydney G. Clark; Abigail Vallie; Sha Huang; Charlie J. Childs; Rachel K. Zwick; Ian Glass; Katherine D. Walton; Ophir D. Klein; Jason R. Spence
作者单位1. Department of Internal Medicine, Division of Gastroenterology, University of Michigan Medical School, Ann Arbor, USA; 2. Graduate Program in Cellular and Molecular Biology, University of Michigan Medical School, Ann Arbor, USA; 3. Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, USA; 4. Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, USA; 5. Department of Cell Biology, NYU Grossman School of Medicine, New York, USA; 6. Regenerative Medicine Institute, NYU Grossman School of Medicine, New York, USA; 7. Department of Pediatrics, Genetic Medicine, University of Washington, Seattle, USA; 8. Program in Craniofacial Biology and Department of Orofacial Sciences, University of California San Francisco, San Francisco, USA; 9. Department of Pediatrics, Cedars-Sinai Guerin Childrens, Los Angeles, USA; 10. Department of Biomedical Engineering, University of Michigan and University of Michigan College of Engineering, Ann Arbor, USA
Mitochondrial-derived vesicles drive budding-type fission of damaged lysosomes
作者Yuanchun Luo; Jianglong Yu; Zhuofan Li; Wanning Li; Le Jiang; Chen Huang; Zhouyi Rong; Long Lin; Yueguang Rong; Chaojun Yan; Zhishui Chen; Jingfeng Tang; He He; Anbing Shi; Zhiyin Song
作者单位1. Department of Pathology, School of Basic Medicine, Institute of Pathology, Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China; 2. College of Life Sciences, Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China; 3. National ‘111’ Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education and Hubei Province), Hubei Key Laboratory of Industrial Microbiology, Hubei University of Technology, Wuhan, China
Lysosomes and lysosomal dysfunction in ageing biology
作者Matthew L. Steinhauser; Yuan Liu; Stacey J. Sukoff Rizzo; Bill B. Chen; Toren Finkel; Jay Xiaojun Tan
作者单位1. Aging Institute, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, Pittsburgh, USA; 2. Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, USA; 3. Center for Human Integrative Physiology, University of Pittsburgh School of Medicine, Pittsburgh, USA; 4. Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, USA; 5. Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, USA; 6. Acute Lung Injury Center of Excellence, University of Pittsburgh, Pittsburgh, USA; 7. Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, USA
Single-cell transcriptomics uncovers endothelial progenitor-like remodelling driving human coronary atherosclerosis progression
作者Fang Yao; Fangzhou Li; Shujie Gai; Yinan Chen; Fei Liu; Xingzhong Zhang; Jun Li; Lin Mao; Liliang Guo; Kun Xing; Juan Huang; Shufang Fu; Yang Sun; Jinhua Chen; Heng Zhang; Yihan Chen; Bingying Zhou; Li Wang; Zhe Zheng
作者单位1. State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; 2. State Key Laboratory of Cardiovascular Disease, Fuwai Shenzhen Hospital, Chinese Academy of Medical Sciences, Shenzhen, China; 3. Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; 4. Department of Pathology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; 5. State Key Laboratory of Cardiovascular Diseases and Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China; 6. National Health Commission Key Laboratory of Cardiovascular Regenerative Medicine, Fuwai Central China Hospital, Central China Branch of National Center for Cardiovascular Diseases, Zhengzhou, China; 7. Key Laboratory of Coronary Heart Disease Risk Prediction and Precision Therapy, Chinese Academy of Medical Sciences, Beijing, China; 8. Institute of Cardiovascular Disease, Henan Academy of Innovations in Medical Science, Zhengzhou, China
Decoding stage-specific functions of PRC2 in early embryogenesis uncovers roles in preimplantation development and primordial germ cell fate
作者Chengjie Zhou; Meng Wang; Zhiyuan Chen; Yi Zhang
作者单位1. Howard Hughes Medical Institute, Boston Children’s Hospital, Boston, USA; 2. Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Boston, USA; 3. Reproductive Sciences Center, Division of Developmental Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, USA; 4. Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, USA; 5. Division of Hematology/Oncology, Department of Pediatrics, Boston Children’s Hospital, Boston, USA; 6. Department of Genetics, Harvard Medical School, Boston, USA; 7. Harvard Stem Cell Institute, Boston, USA
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