Nature Cancer

作者Jonathan C. M. Wan; Nicholas McGranahan; Charles Swanton

作者单位1. Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK; 2. Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK; 3. Department of Oncology, University College London Hospitals, London, UK; 4. Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK; 5. Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK

作者Shani Dror; Inbal Wortzel; Serena Lucotti; Yura Seo; Jianlong Li; Lee Shaashua; Irina Matei; Nancy Boudreau; Haiying Zhang; Maider Astorkia-Amiama; Doron Betel; Han Sang Kim; Jai Prakash; Jacqueline Bromberg; David Lyden

作者单位1. Children’s Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children’s Health, Meyer Cancer Center, Weill Cornell Medicine, New York, USA; 2. Gray Faculty of Medical & Health Sciences, Jan Koum Nanocenter, Tel Aviv University, Tel Aviv, Israel; 3. Yonsei Cancer Center, Division of Medical Oncology, Department of Internal Medicine, Graduate School of Medical Science, Brain Korea 21 FOUR Project, Yonsei University College of Medicine, Seoul, Republic of Korea; 4. Department of Orthopedic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China; 5. Applied Bioinformatics Core, Weill Cornell Medicine, New York, USA; 6. Institute for Computational Biomedicine, Weill Cornell Medicine, New York, USA; 7. Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine, New York, USA; 8. Advanced Bioengineering and Therapeutics group, Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, The Netherlands; 9. Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA

作者Hongnan Mo; Yuee Teng; Li Cai; Huihui Li; Xinhong Wu; Jing Yao; Yu Wang; Dan Lv; Xuenan Peng; Shuchun Wang; Rongrong Chen; Xin Yi; Qingyao Shang; Youwen He; Ji Liu; Zheng Pang; Tianyu Feng; Fei Ma

作者单位1. National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; 2. The First Hospital of China Medical University, Shenyang, China; 3. HarBin Medical University Cancer Hospital, HarBin, China; 4. Cancer Hospital of Shandong First Medical University, Jinan, China; 5. Hubei Cancer Hospital, Wuhan, China; 6. Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; 7. Shanxi Cancer Hospital, Taiyuan, China; 8. Beijing Geneplus Technology Co., Ltd, Beijing, China; 9. Duke University School of Medicine, Durham, USA; 10. Jiangsu Hengrui Pharmaceuticals Co., Ltd, Shanghai, China

作者Remi Hatinguais; Stan Verjans; Joana Gomes; Sandra J. van Vliet

作者单位1. Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; 2. Cancer Biology and Immunology, Cancer Center Amsterdam, Amsterdam, the Netherlands; 3. Cancer Immunology, Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, the Netherlands; 4. i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; 5. IPATIMUP- Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal

作者Siyao Guo; Yutong Zou; Canfeng Zhang; Hui Han; Yishan Li; Yucong Sun; Zhaoyu Wang; Wanrui Zhang; Jiang Zhang; Yuli Gan; Qiang Zhang; Jieyi Ma; Siyi Zheng; Hongshen Qiu; Yan Zhu; Wange Lu; Yong Bao; Meng Zhao; Shuibin Lin

作者单位1. Department of Laboratory Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; 2. Center for Translational Medicine, Precision Medicine Institute, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; 3. Department of Musculoskeletal Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; 4. Advanced Medical Technology Center, The First Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-sen University Guangzhou, Guangdong, China; 5. Key Laboratory of Stem Cells and Tissue Engineering (Ministry of Education), Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China; 6. Department of Radiation Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; 7. Innovative Cancer Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China; 8. State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China; 9. Institute for Frontier Interdisciplinary Research in Health Sciences and Technology, Sun Yat-sen University, Guangzhou, Guangdong, China

作者Xingwen Wang; Yi Zhang; Jiangwen Ma; Qingyu Lin; Zhenghang Wang; Guixue Hou; Yutong Wei; Minqiao Lu; Meiqi Wang; Tianyu Li; Shanliang Zheng; Wenxin Zhang; Yafan Gong; Tianqi Guan; Hao Liu; Xiaotian Zhang; Li Li; Ying Hu

作者单位1. School of Life Science and Technology, Harbin Institute of Technology, Harbin, China; 2. Key Laboratory of Major Chronic Disease Prevention and Control Science and Technology and Intelligent Equipment, Ministry of Industry and Information Technology, Zhengzhou Advanced Research Institute, Harbin Institute of Technology, Zhengzhou, China; 3. Space Environment Simulation Research Infrastructure, Harbin, China; 4. State Key Laboratory of Space Environment Interation with Matters, Harbin Institute of Technology, Harbin, China; 5. BGI-SHENZHEN, Shenzhen, China; 6. Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, China; 7. The third affiliated hospital of Harbin Medical University, Harbin, China

作者Franz J. Zemp; Zackariah Breckenridge; Hyojin Song; Gurveer S. Gill; Taye L. Louie; Kiran Narta; Hongrui Liu; Yeon Suh; Louisa Guignard; Edna Ayerim Mandujano-Tinoco; Nicolás Collao; Joanna Pyczek; Kristofor K. Ellestad; Jada Curry; Jethro Langley; Cini John; Laura K. Mah; Jahanara Rajwani; Danyel Evseev; Madison Turk; Sacha Benaoudia; Jonathan Alex; Victor Naumenko; Varsha Thoppey Manoharan; Mobina Kazemi Mehrabadi; Harmony A. Smith; Geneece N. Y. Gilbert; Aaron Gillmor; Ted B. Verhey; Hayley M. Todesco; Katalin Osz; Bo-Young Ahn; Ana Bogossian; Colleen Anderson; Saif Sikdar; Shahrbano Rukunuddin; Tarek A. Bismar; Daniel Y. C. Heng; Keith Lawson; W. Marston Linehan; Haley Pedersen; Paul M. K. Gordon; John B. McIntyre; John MacGregor; Livia Garzia; Kathy Brodeur-Robb; Lisa DiFrancesco; Travis Ogilvie; Patrick Schöffski; Agnieszka Wozniak; Robert A. Holt; John Bell; Donna L. Senger; Victor Lewis; Michael Monument; Omar Khan; Lou Baudrier; Pierre Billon; Vincent Gabriel; Jeff Biernaskie; Kyle Potts; Kiril Trpkov; Kevin Hay; Jennifer Quizi; Jennifer Chan; Ramy Saleh; Jan Willem Henning; Nicole L. Prokopishyn; Mona Shafey; A. Sorana Morrissy; Douglas J. Mahoney

作者单位1. Riddell Centre for Cancer Immunotherapy, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Canada; 2. Alberta Children’s Hospital Research Institute, University of Calgary, Calgary, Canada; 3. Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Canada; 4. Department of Microbiology, Immunology and Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Canada; 5. Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada; 6. Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada; 7. Robson DNA Science Centre, University of Calgary, Calgary, Canada; 8. Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Canada; 9. Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, Canada; 10. Division of Urology, Department of Surgery, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, Canada; 11. Urologic Oncology Branch, National Cancer Institute, Bethesda, USA; 12. Centre for Health Genomics and Informatics, Cumming School of Medicine, University of Calgary, Calgary, Canada; 13. Cancer Translational Research Core Laboratory, Arthur JE Child Comprehensive Cancer Centre, Calgary, Canada; 14. Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, Canada; 15. Department of Surgery, McGill University, Montreal, Canada; 16. Gerald Bronfman Department of Oncology, McGill University, Montreal, Canada; 17. C17 Council, Edmonton, Canada; 18. Department of General Medical Oncology, Leuven Cancer Institute, University Hospitals Leuven, KU Leuven, Belgium; 19. Department of Oncology, Research Unit Laboratory of Experimental Oncology, KU Leuven, Belgium; 20. Department of Medical Genetics, University of British Columbia, Vancouver, Canada; 21. Canada’s Michael Smith Genome Sciences Centre, Vancouver, Canada; 22. Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada; 23. Ottawa Hospital Research Institute, Ottawa, Canada; 24. Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Canada; 25. Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada; 26. Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Canada; 27. Department of Surgery and Orthopedic Surgery, Cumming School of Medicine, University of Calgary, Calgary, Canada; 28. Dept of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, Canada; 29. McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada; 30. Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada; 31. Diagnostic and Molecular Pathology, Alberta Precision Laboratories, Calgary, Canada; 32. Department of Medicine, Division of Hematology and Hematologic Malignancies, Cumming School of Medicine, University of Calgary, Calgary, Canada; 33. Center for Innovative Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Canada; 34. Division of Medical Oncology, McGill University Health Centre, Montreal, Canada; 35. Arthur Child Comprehensive Cancer Centre, Calgary, Canada

作者Lukas Bunse; Katharina Lindner; Antje Wick; Angelika Freitag; Lisa-Marie Lanz; Dominic Edelmann; Abigail Suwala; Michael O. Breckwoldt; Inga Harting; Felix Sahm; Richard F. Schlenk; Anita Schmitt; Oliver Schnell; Jörg Hense; Martin Misch; Dietmar Krex; Monika Denk; Juliane Walz; Joachim P. Steinbach; Andreas von Deimling; Michael Schmitt; Theresa Bunse; Ghazaleh Tabatabai; Martin Bendszus; Isabel Poschke; Wolfgang Wick; Michael Platten

作者单位1. DKTK (German Cancer Consortium) Clinical Cooperation Unit (CCU) Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany; 2. Department of Neurology, Medical Faculty Mannheim, MCTN, University of Heidelberg, Mannheim, Germany; 3. German Cancer Consortium (DKTK), DKFZ, Core Center, Heidelberg, Germany; 4. Hertie Network of Excellence in Clinical Neuroscience, Tübingen, Germany; 5. DKFZ-Hector Cancer Institute at University Medical Center Mannheim, Mannheim, Germany; 6. Cluster of Excellence SynthImmune (EXC 3018/1) “Engineering Immune function with Synthetic Biology”, University of Heidelberg, Mannheim, Germany; 7. Immune Monitoring Unit, National Center for Tumor Diseases (NCT), Heidelberg, Germany; 8. Neurology Clinic and European Center for Neurooncology (EZN), Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany; 9. NCT Trial Management and Services, NCT, and German Cancer Research Center (DKFZ), Heidelberg, Germany; 10. Department of Neuropathology, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany; 11. Department of Neuroradiology, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany; 12. DKTK CCU Neuropathology, DKFZ, Heidelberg, Germany; 13. Department of Medical Oncology, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany; 14. Department of Internal Medicine V, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany; 15. Neurosurgery Clinic, University Hospital Erlangen, Erlangen, Germany; 16. Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; 17. Department of Neurosurgery, Charité Medical Center, University of Berlin, Berlin, Germany; 18. Technische Universität Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, Department of Neurosurgery, Dresden, Germany; 19. Cluster of Excellence iFIT (EXC2180) ‘Image-Guided and Functionally Instructed Tumor Therapies’, University of Tübingen, Tübingen, Germany; 20. Department of Peptide-based Immunotherapy, Institute of Immunology, University and University Hospital Tübingen, Tübingen, Germany; 21. German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), partner site Tübingen, Tübingen, Germany; 22. Dr. Senckenberg Institute of Neurooncology, Frankfurt, Germany; 23. Department of Neurology and Neuro-Oncology, University Hospital Tübingen, Hertie Institute for Clinical Brain Research, Eberhard Karls University Tübingen, Tübingen, Germany; 24. Center for Neuro-Oncology, CCC Tübingen-Stuttgart in CCC-SW, Tübingen, Germany; 25. DKTK CCU Neurooncology, DKFZ, Heidelberg, Germany; 26. Helmholtz Institute for Translational Oncology (HI-TRON) Mainz, German Cancer Research Center, Mainz, Germany

作者Ya-Lan Tao; Dong-Hong Wu; Qin Zhou; Kun-Yu Yang; Feng Jin; Xiao-Dong Zhu; Mei Shi; Guo-Qing Hu; Yan Sun; Hong-Fen Wu; Hui Wu; Qin Lin; Hui Wang; Ye Tian; Ning Zhang; Xi-Cheng Wang; Liang-Fang Shen; Zheng-Zheng Liu; Jing Huang; Xiu-Ling Luo; Ling Li; Jian Zang; Qi Mei; Bao-Min Zheng; Dan Yue; Jing Xu; San-Gang Wu; Lei Chen; Wen-Fei Li; Guan-Qun Zhou; Rui Sun; Rui Guo; Yuan Zhang; Cheng Xu; Jia-Wei Lv; Ying Guo; Hui-Xia Feng; Ling-Long Tang; Fang-Yun Xie; Xu Liu; Ying Sun; Jun Ma; Yan-Ping Mao; Yu-Pei Chen

作者单位1. Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China; 2. Department of Oncology, Xiangya Hospital, Central South University, Changsha, China; 3. Department of Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; 4. Department of Oncology, Affiliated Hospital of Guizhou Medical University, Guiyang, China; 5. Department of Radiation Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Department of Oncology, Affiliated Wuming Hospital of Guangxi Medical University, Nanning, China; 6. Department of Radiation Oncology, Xijing Hospital of Fourth Military Medical University, Xi’an, China; 7. Department of Oncology, Cancer Center, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China; 8. Department of Radiation Oncology, Peking University Cancer Hospital, Beijing, China; 9. Department of Radiation Oncology, Jilin Cancer Hospital, Changchun, China; 10. Department of Radiation Oncology, Henan Cancer Hospital, Zhengzhou, China; 11. Department of Radiation Oncology, Xiamen Cancer Center, The First Affiliated Hospital of Xiamen University, Xiamen, China; 12. Department of Radiation Oncology, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China; 13. Department of Radiation Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China; 14. Department of Radiation Oncology, The First People’s Hospital of Foshan, Foshan, China; 15. Department of Radiation Oncology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China; 16. Clinical Trials Center, Sun Yat-sen University Cancer Center, Guangzhou, China

作者Xin He; Lei Zhang; Yang Li; Song-Bai Liu; Zheng Li; Haojie Dong; Genevieve E. Baker; Le Xuan Truong Nguyen; Wei Chen; Jinhui Wang; Zhilian Jia; Xiyuan Lu; Yi-Chun Lin; Zunsong Hu; Umesh Prasad Yadav; Meng Liu; Lianjun Zhang; Zhenhua Chen; Xiwei Wu; Jianjun Chen; Chun-Wei Chen; Stefano Tiziani; Weidong Hu; Ya-Huei Kuo; Sheng-Li Xue; Yong Zhang; Min Li; Yaoqiu Zhu; Guido Marcucci; Zhaohui Gu; J. Jefferson P. Perry; Yun Lyna Luo; Ling Li

作者单位1. Department of Hematological Malignancies Translational Science, Beckman Research Institute, City of Hope Medical Center, Duarte, USA; 2. Department of Hematology, Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fujian Medical University Union Hospital, Fuzhou, China; 3. Suzhou Key Laboratory of Medical Biotechnology, Suzhou Vocational Health College, Suzhou, China; 4. National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China; 5. Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China; 6. Department of Molecular Diagnostics and Experimental Therapeutics, Beckman Research Institute, City of Hope Medical Center, Duarte, USA; 7. Integrative Genomics Core, Beckman Research Institute, City of Hope Medical Center, Duarte, USA; 8. Department of Computational and Quantitative Medicine & Systems Biology, City of Hope Medical Center, Duarte, USA; 9. Department of Nutritional Sciences, The University of Texas at Austin, Austin, USA; 10. College of Pharmacy, Western University of Health Sciences, Pomona, USA; 11. Department of Immunology and Theranostics, Beckman Research Institute, City of Hope Medical Center, Duarte, USA; 12. Department of Pharmacology and Pharmaceutical Sciences, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, USA; 13. Division of Biostatistics, Department of Computational and Quantitative Medicine, Beckman Research Institute, City of Hope Medical Center, Duarte, USA