医学
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20 篇有效样本 · 按发表日期由新到旧排列
审稿天数=录用日期-收稿日期;保留 PDF/DOI/网页源链接
Relevance‐Based Score for MIPD Model Selection: Systematic Review and External Evaluation of popPK Tacrolimus Models in Adult Transplant Recipients
作者Samuel Baroudi; Bénédicte Franck; Jean‐Baptiste Woillard; Ntobe‐Bunkete Béni; Emmanuelle Comets; Florian Lemaitre
作者单位1. Inserm, EHESP, Irset (Institut de Recherche en santé, Environnement et Travail), UMR_S 1085 Univ. Rennes Rennes France; 2. FHU SUPORT Rennes France; 3. Department of Pharmacology, Toxicology and Pharmacovigilance CHU de Limoges Limoges France; 4. Pharmacology & Transplantation, INSERM U1248 Université de Limoges Limoges France; 5. Inserm, IAME Université Paris Cité and Université Sorbonne Paris Nord Paris France
A Systematic Review of Published Physiologically Based Pharmacokinetic Models for Drug Excretion Into Human Breastmilk: Knowledge Gaps and Opportunities to Optimize Reporting and Modeling Practices
作者Joshua Kiptoo; Davies Otieno; Kenta Yoshida; Neel Deferm; Aida Nakayiwa Kawuma; Francis Williams Ojara; Adeniyi Olagunju; Jackson K. Mukonzo; Catriona Waitt
作者单位1. Department of Pharmacology & Therapeutics Makerere University Kampala Uganda; 2. Infectious Diseases Institute, Makerere University Kampala Uganda; 3. Department of Pharmacy Mbarara University of Science & Technology Mbarara Uganda; 4. Department of Clinical Pharmacology Genentech Inc. South San Francisco California USA; 5. Predictive Technologies Division Certara UK Limited Sheffield UK; 6. Pharmides BV Pelt Belgium; 7. Pumas‐AI Inc. Dover Delaware USA; 8. Department of Pharmacology Gulu University Gulu Uganda; 9. Department of Biochemistry, Cell and Systems Biology University of Liverpool Liverpool UK; 10. Department of Women's and Children's Health University of Liverpool Liverpool UK
Modeling Treatment Response in Tuberculosis Early Bactericidal Activity Trials
作者Mairi C. W. McClean; Simon E. Koele; Julia Dreisbach; Susanne Mirold‐Mei; Fred Njeleka; Daniel Mapamba; Bariki Mtafya; Patrick P. J. Phillips; Veronique R. De Jager; Rodney Dawson; Kim Narunsky; Andreas H. Diacon; Elin M. Svensson; Norbert Heinrich; Francesco Paolo Casale; Michael Hoelscher
作者单位1. Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital Munich Germany; 2. Institute of AI for Health, Helmholtz Center Munich—German Research Center for Environmental Health Neuherberg Germany; 3. Institute for Medical Information Processing, Biometry, and Epidemiology (IBE), Pettenkofer School of Public Health LMU Medizin, Ludwig‐Maximilians‐Universität München Munich Germany; 4. Helmholtz Pioneer Campus Helmholtz Zentrum München—German Research Center for Environmental Health Neuherberg Germany; 5. Department of Pharmacy, Pharmacology, and Toxicology Radboud Institute for Medical Innovation, Radboud University Medical Center Nijmegen the Netherlands; 6. German Center for Infection Research (DZIF), Munich Partner Site Munich Germany; 7. National Institute for Medical Research‐Mbeya Medical Research Center Mbeya Tanzania; 8. UCSF Center for Tuberculosis University of California San Francisco San Francisco California USA; 9. TASK Applied Science Clinical Research Center Cape Town South Africa; 10. Department of Medicine University of Cape Town Lung Institute Cape Town South Africa; 11. Department of Pharmacy Uppsala University Uppsala Sweden; 12. Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology, Infection, and Pandemic Research Munich Germany; 13. School of Computation, Information and Technology Technical University of Munich Garching Germany; 14. Unit Global Health, Helmholtz Zentrum München—German Research Centre for Environmental Health Neuherberg Germany
Beyond Traditional Covariates: An Interpretable Machine Learning Workflow for Improved Hybrid Pharmacometric Modeling
作者Freek J. A. Relouw; Jort J. M. T. Lokers; Tim Preijers; Sebastiaan D. T. Sassen; Natal A. W. van Riel; Birgit C. P. Koch
作者单位1. Department of Biomedical Engineering Eindhoven University of Technology Eindhoven the Netherlands; 2. Department of Hospital Pharmacy Erasmus University Medical Center Rotterdam the Netherlands; 3. Rotterdam Clinical Pharmacometrics Group Rotterdam the Netherlands; 4. Division of Neonatology, Department of Neonatal & Pediatric ICU Erasmus MC Rotterdam the Netherlands; 5. Department of Intensive Care Medicine Radboud University Medical Center Nijmegen the Netherlands
Bayesian Workflow for Minimal PBPK Models: Case Study of Dapagliflozin
作者Anna Mikhailova; Kirill Peskov; Gabriel Helmlinger; Victor Sokolov
作者单位1. M&S Decisions Dubai UAE; 2. Marchuk Institute of Numerical Mathematics RAS Moscow Russian Federation; 3. Research Center of Model‐Informed Drug Development Sechenov First Moscow State Medical University Moscow Russian Federation; 4. Quantitative Medicines Lexington Massachusetts USA
Machine Learning Enables Rapid Prediction of Acid‐Reducing Agent Drug Interactions: A Streamlined Complement to PBPK Modeling
作者Yuanfang Qin; Lehua Yu; Tao Chen; Yonghui Zuo; Hongyun Wang; Guoping Yang; Qi Pei
作者单位1. Department of Pharmacy The Third Xiangya Hospital, Central South University Changsha China; 2. Center for Clinical Pharmacology The Third Xiangya Hospital, Central South University Changsha China; 3. Shanghai PharmoGo Co., Ltd Shanghai P. R. China; 4. Changsha Xutong Technology Co., Ltd Changsha China; 5. Clinical Pharmacology Research Center Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Complex Severe and Rare Diseases Beijing China; 6. Xiangya School of Pharmaceutical Sciences Central South University Changsha China
Utilizing Virtual Clinical Trials to Inform Target Coverage That Drives RSV Antiviral Efficacy
作者J. Cody Herron; Kathryn G. Link; Natalie Meacham; Negar Niki Alami; Daniel W. Brookes; Elaine Thomas; Jan Adams; Sima S. Toussi; Ryan Franke; Cynthia J. Musante; Isabel Najera; Richard Allen; Britton Boras
作者单位1. Pfizer Inc. Translational Clinical Sciences Cambridge Massachusetts USA; 2. Pfizer Inc., R&D Pearl River New York USA; 3. Pfizer Inc., R&D, UK London UK; 4. Pfizer Inc. Preclinical & Translational Sciences La Jolla California USA
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