医学
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19 篇有效样本 · 按发表日期由新到旧排列
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4‐(5′‐Dimethylamino)‐Naphthalenesulfonyl‐2(3 H )‐Benzoxazolone (W3D) Ameliorated COPD Lung Injury Through Regulating Macrophage Polarization Mediated by Glycolysis
作者Qikai Su; Yichen Yang; Zhichao Ren; Qing‐shan Li; Rui Ge; Li Tang
作者单位1. School of Pharmacy, Medicinal Basic Research Innovation Center of Chronic Kidney Disease, Ministry of Education, Shanxi Provincial Key Laboratory of Drug Synthesis and Novel Pharmaceutical Preparation Technology Shanxi Medical University Taiyuan China; 2. Shanxi Key Laboratory of Innovative Drug for the Treatment of Serious Diseases Basing on the Chronic Inflammation Shanxi University of Traditional Chinese Medicine Shanxi China
Thiazole‐Derived Dual EGFR/CDK‐2 Inhibitors: Rational Design, Synthesis, In Vitro Anticancer Evaluation, Mechanistic Profiling, and Computational Binding Analysis
作者Rowida Nasr; Mohamed S. Nafie; Hesham Haffez; Mohamed Ahmed A. Moustafa; Mohamed M. El‐kerdawy; Ahmed R. Ali
作者单位1. Department of Medicinal Chemistry Faculty of Pharmacy, Mansoura University Mansoura Egypt; 2. Department of Chemistry, College of Sciences University of Sharjah Sharjah UAE; 3. Chemistry Department, Faculty of Science Suez Canal University Ismailia Egypt; 4. Biochemistry and Molecular Biology Department, Faculty of Pharmacy Capital University (formerly Helwan University) Cairo Egypt; 5. Center of Scientific Excellence “Helwan Structural Biology Research, (HSBR)” Capital University (formerly Helwan University) Cairo Egypt; 6. Medicinal Chemistry Department, Faculty of Pharmacy Egypt‐Japan University of Science and Technology (E‐JUST) Alexandria Egypt
Evaluation of Novel Cloxyquin Analogs for K 2P 18.1 Channel Modulation
作者Jasmin Sörgel; Marcel Kloth; Henning Klaasen; Sven G. Meuth; Thomas Budde; Bart Jan Ravoo; Julian A. Schreiber
作者单位1. Institute of Pharmaceutical and Medicinal Chemistry University of Münster Münster NRW Germany; 2. Organisch‐Chemisches Institut University of Münster Münster NRW Germany; 3. Department of Neurology University Hospital Münster Münster NRW Germany; 4. Institute of Physiology University of Münster Münster NRW Germany; 5. Center for Soft Nanoscience University of Münster Münster NRW Germany
Mutation‐Induced Pocket Deactivation: How Ser353/Pro245 Alters K Ca 2.2 vs. K Ca 3.1 Ligand Selectivity
作者Matteo Gozzi; Joana Massa; Oliver Koch
作者单位1. GRK 2515, Chemical Biology of Ion Channels (Chembion) University of Münster Münster Germany; 2. Institute of Pharmaceutical and Medicinal Chemistry University of Münster Münster Germany
Recent Overview on the Molecular Hybrids Integrated With Benzosuberone/Benzo[7]annulene Derivatives as Multi‐Target Therapeutics
作者Mohamed S. Nafie; Kamal M. Dawood; Mohamed K. Diab; Ashraf A. Abbas
作者单位1. Department of Chemistry, College of Sciences University of Sharjah Sharjah UAE; 2. Bioinformatics and Functional Genomics Research Group, Research Institute of Sciences and Engineering (RISE) University of Sharjah Sharjah UAE; 3. Department of Chemistry, Faculty of Science Suez Canal University Ismailia Egypt; 4. Department of Chemistry, Faculty of Science Cairo University Giza Egypt; 5. Pest Physiology Department, Agricultural Research Center Plant Protection Research Institute Giza Egypt
Total Synthesis of Marine Natural Product Sunshinamide via Macrolactonization
作者Yi Lu; Yuanmu Zhang; Hanqi Wang; Ya Gao; Ahmed Sabt; Wei Zhang; Xinsheng Lei
作者单位1. School of Pharmacy Fudan University Shanghai China; 2. Shanghai Forxine Pharmaceutical Co. Ltd. Shanghai China; 3. Chemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Institute National Research Centre Cairo Egypt
Emerging Indole and Azaindole Hybrid Agents for Leukemia Therapy: Recent Research Advances and Therapeutic Potential
作者Yanjing Cheng; Lianlian Chen; Danchen Zhao; Jun Yu; Yafei Zhuang
作者单位1. School of Pharmacy, Xianning Medical College Hubei University of Science and Technology Xianning China; 2. School of Public Health and Nursing, Xianning Medical College Hubei University of Science and Technology Xianning China
Electro‐Mechanical Uncoupling of K V 7.1 Voltage Sensor and Pore by 1,4‐Benzodiazepines Is Modulated by Decoration of Position 1
作者Florian Roßner; Thomas Jepps; Bo Hjorth Bentzen; Nathalie Strutz‐Seebohm; Bernhard Wünsch; Guiscard Seebohm
作者单位1. GRK 2515, Chemical Biology of Ion Channels (Chembion) Universität Münster Münster Germany; 2. Institute of Pharmaceutical and Medicinal Chemistry University of Münster Münster Germany; 3. Department of Biomedical Sciences University of Copenhagen Copenhagen Denmark; 4. Department of Cardiovascular Medicine, Institute for Genetics of Heart Diseases (IfGH) University Hospital Münster Münster Germany
Gastroprotective Activity of Myrtenol Derivatives Obtained by Biocatalytic Esterification and Photooxidation
作者Ana Flávia Seraine Custódio Viana; Mateusz Kutyła; Hélio de Barros Fernandes; Boris Timah Acha; Gabriel Henrique Oliveira; Rita de Cássia Meneses Oliveira; Marek Stankevič; Mariusz Trytek
作者单位1. Post‐Graduate Program of Pharmacology Federal University of Piauí Teresina Piauí Brazil; 2. Medicinal Plants Research Center (NPPM), Health Sciences Center Federal University of Piauí Teresina Piauí Brazil; 3. State University of Maranhão Campus Santa Inês Maranhão Brazil; 4. Department of Industrial and Environmental Microbiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences Maria Curie‐Skłodowska University Lublin Poland; 5. Department of Organic Chemistry and Crystallochemistry, Faculty of Chemistry, Institute of Chemistry Sciences Maria Curie‐Skłodowska University Lublin Poland
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