Biology
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BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
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Activity of natural single nucleotide variants of human alkyladenine DNA glycosylase AAG R145H, G163S and R197C involved in DNA binding
AuthorsO.A. Kladova; T.E. Tyugashev; A.A. Miroshnikov; A.S. Bakman; A.A. Kuznetsova
AffiliationsInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russia
Structural and energetic landscape of the human HOP-PrPC Axis: Multi-domain stabilization and peptide-mediated disruption by melittin
AuthorsGagandeep Singh; Tapan Kumar Chaudhuri
AffiliationsKusuma School of Biological Sciences, Indian Institute of Technology, Delhi, India; Waterlab, Delhi Pollution Control Committee, Delhi, India
Native structure of the therapeutic IgG4 α4β5 integrin antibody natalizumab
AuthorsVictor G. Chrone; Johan C. Jespersen; Daut C. Asani; Jens Hieronymus; Soumik Ray; Nicole H. Trier; Jette L. Frederiksen; Peter Højrup; Gunnar Houen
AffiliationsDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, DK-5230 Odense, Denmark; Alphalyse A/S, Stenhuggervej, DK-5230 Odense, Denmark; Department of Neurology and Translational Research Center (TRACE), Rigshospitalet, Glostrup, Copenhagen, Denmark; Department of Biotechnology and Biomedicine, Technical University of Denmark, DTU, DK-2800 Lyngby, Denmark
Systematic identification of species-specific allosteric sites in bacterial glycolytic enzymes: Hexokinase, phosphoglucose isomerase, phosphoglycerate kinase, and enolase
AuthorsDefne Alnigenis; Florihana Brina; Ilknur Kocal; Latife Sude Vural; Ebru Demet Akten
AffiliationsDepartment of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Kadir Has University, Istanbul, Turkey; Graduate Program of Computational Sciences and Engineering, Graduate School of Science and Engineering, Kadir Has University, Istanbul, Turkey
Subcellular proteomic analysis of the DDR2 interactome in a neuronal cell model exposed to Aβ42
AuthorsRussa Das; Debashis Mukhopadhyay
AffiliationsBiophysical Science Division, Saha Institute of Nuclear Physics, A CI of Homi Bhabha National Institute, 1/AF Bidhannagar, Kolkata 700064, India
Exploring the proteomic landscape of THP-1 monocytes through two-challenge LPS induction
AuthorsCassandra Cianciarulo; Ilona Turek; Siti Saleha Binte Mohamed Yakob Adil; Santosh Tata Rama Bhadra Rao; Keshava Datta; Rohan Lowe; Trang H. Nguyen; Terri Meehan-Andrews; Joseph Tucci; Tony Velkov; Helen Irving
AffiliationsHolsworth Biomedical Research Centre, Department of Rural Clinical Sciences, La Trobe Rural Health School, La Trobe University, Bendigo, VIC 3552, Australia; La Trobe Institute for Molecular Sciences, La Trobe University, Bendigo, VIC 3552, Australia; Australian Centre for Disease Preparedness, Commonwealth Scientific and Industrial Research Organisation, East Geelong, VIC 3220, Australia; La Trobe Institute of Molecular Sciences, La Trobe University, Bundoora, VIC 3086, Australia; Monash Biomedicine Discovery Institute, Department of Pharmacology, Monash University, Clayton, VIC 3800, Australia
tRNA methyltransferase (TRDMT1/DNMT2) participates in network of RNA modification in the Moss Physcomitrium patens
AuthorsYashika Kanojia; Darshika Singh; Nikita Wadhwa; Meenu Kapoor
AffiliationsUniversity School of Biotechnology, Guru Gobind Singh Indraprastha University, Sector 16C, Dwarka, New Delhi 110078, India
Activity-guided identification, cloning, heterologous expression, and characterization of a highly thermostable mitochondrial superoxide dismutase from Lantana camara
AuthorsHimanshu; Mahima Chauhan; Mahesh Kulharia; Arun Kumar
AffiliationsMolecular Biology & Biochemistry Lab, Fermentation and Phytofarming Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Post Box No. 6, Palampur-176 061, Himachal Pradesh, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, Uttar Pradesh, India; Centre for Computational Biology and Bioinformatics, Central University of Himachal Pradesh, Kangra 176206, India
Biochemical characterization and assay development for adenylosuccinate synthetase Rv0357c from Mycobacterium tuberculosis
AuthorsVigyasa Singh; Ran Zhang; Ke Chen; Zhong Li; Hongmin Li
AffiliationsDepartment of Pharmacology and Toxicology, R Ken Coit College of Pharmacy, 1703 E Mabel St, Tucson, AZ 85721-0207, USA; The BIO5 Institute, The University of Arizona, Tucson, AZ 85721, USA; Biological Chemistry Program, Department of Chemistry and Biochemistry, College of Science & College of Medicine, The University of Arizona, Tucson, AZ 85721, USA; Department of Molecular & Cellular Biology, College of Science, The University of Arizona, Tucson, AZ 85721, USA
In silico structural characterization of the geranyl pyrophosphate synthase (GPPS) large subunit from Catharanthus roseus
AuthorsKarunesh Yadav; Km Akanksha Gupta; Dinesh A. Nagegowda; Prema G. Vasudev
AffiliationsPlant Biotechnology Division, CSIR- Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) P.O. CIMAP, Near Kukrail Picnic Spot, Lucknow 226015, India; Academy of Scientific and Innovative Research (AcSIR), Kamala Nehru Nagar, Ghaziabad 201002, India; CSIR-CIMAP Research Centre, Allalasandra, GKVK Post, Bengaluru 560065, India
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