Biology
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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SHH mediated human dopaminergic neuron differentiation is facilitated by transcription factor ZIC3
AuthorsPreethi Sheshadri; Smitha Bhaskar; Jeevan Gowda; Shreetama Banerjee; Michael R. Duchen; Jyothi Prasanna; Anujith Kumar
AffiliationsManipal Institute of Regenerative Medicine, Manipal academy of higher education, Manipal, Karnataka, 576104, India; Department of cell and developmental biology, University College London, WC1E6BT, London, United Kingdom
SUSD2 suppresses colorectal cancer progression by activating NF-κB pathway to regulate NOX4-mediated oxidative stress
AuthorsDaying Wu; Long Chen; Sizhe Zhao; Xiangcong Zeng; Gengrong Liu; Guiling Li; Hong Ma; Bin Li; Ai Huang
AffiliationsCancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China; Institute of Radiation Oncology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China; Hubei Key Laboratory of Precision Radiation Oncology, Wuhan, 430022, China; Department of Neurosurgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China; School of Pharmacy, Hubei University of Science and Technology, Xianning, 437000, China; Department of Oncology and Hematology, Qianjiang Central Hospital of Hubei Province, Qianjiang, 433100, China; Department of Anesthesiology, General Hospital of the Central Theater Command, Wuhan, 430061, China
Microenvironment-derived APP promotes osteosarcoma malignant phenotypes and induces macrophage M2 polarization via CD74
AuthorsChunyu Chen; Xuelei Zhang; Qifeng Tao; Yuping Lan
AffiliationsDepartment of Orthopedics, Chengdu 363th Hospital Affiliated to Southwest Medical University, Chengdu 610041, Sichuan Province, China; Department of Orthopedics, Chengdu No. 1 People's Hospital, Chengdu 610095, Sichuan Province, China; Department of Orthopedics, Panzhihua Municipal Central Hospital, Panzhihua 617067, Sichuan Province, China
Salvianolic acid B enhances adipose-derived stem cells (ADSCs)-mediated perforator flap survival through antioxidative and anti-apoptotic mechanisms
AuthorsLiqin Yuan; Chunjie He; Kai Yang; Xiang Xiong
AffiliationsDepartment of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, China; Department of Plastic and Aesthetic (Burn) Surgery, The Second Xiangya Hospital, Central South University, Changsha, 410011, China
GSK3β-FBXW7 axis regulates MAFB protein stability through ubiquitin-mediated proteasome degradation
AuthorsSangita Chowdhury; Prasannajit Sahoo; Agniv Shome; Swati Srivastava; Vishal Upadhyay; Shivkant Mishra; A.K. Trivedi
AffiliationsDivision of Cancer Biology, CSIR-Central Drug Research Institute, Sector-10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, UP, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India
Targeted analysis of salicylate binding partners in renal epithelial cells reveals major AMPK dependency
AuthorsAnish A. Kanhai; Kirsten Lodder; Lisanne E. Wisse; Laura Louzao-Martinez; Hester Bange; Leo S. Price; Wouter N. Leonhard; Dorien J.M. Peters
AffiliationsDepartment of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands; Crown BioScience Netherlands B.V., Leiden, the Netherlands
NCAPD2 facilitates ovarian cancer progression via MYC-mediated unfolded protein response
AuthorsGuoying Cui; Hongqi Li; Yanqiu Wang; Mingjun Fan
AffiliationsDepartment of Obstetrics and Gynecology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China; Operating Room, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, Shandong, China
The mechanism of SOX4/IGF2BP3/TRIB3 axis inhibiting autophagy and aggravating liver injury in sepsis
AuthorsWenjun Zhao; Jing Zhang; Liang Zhang; Erchun Hong; Min Shao
AffiliationsDepartment of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China; Department of Emergency Medicine, Central Hospital of Bengbu (The Third People's Hospital of Bengbu), Bengbu, Anhui, China
TRIM31 regulates neutrophilic asthma by suppressing IL-17 pathway through decreasing the M1-linked ubiquitination of TRAF6
AuthorsYuchun Liu; Lifeng Li; Chengbo Wang; Xiangzhan Zhu; Kang Cheng; Xiaomin Sun
AffiliationsHenan International Joint Laboratory of Children's Infectious Diseases, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital Zhengzhou Children's Hospital, Zhengzhou, 450000, China; Institute of Biomedical Sciences, Henan Academy of Sciences, Zhengzhou, 450000, China; Henan Province Children's Disease Clinical Medical Research Center, Children's Hospital Affiliated of Zhengzhou University, Henan Children's Hospital Zhengzhou Children's Hospital, Zhengzhou, 450000, China
The EPAC inhibitor ESI-09 attenuates NF-κB signalling in vascular cells
AuthorsJolanta Wiejak; Frederick G. Powell; Paul Burgoyne; Graeme Barker; Stephen J. Yarwood
AffiliationsHeriot-Watt University, Institute of Biological Chemistry, Biophysics and Bioengineering, Edinburgh, EH14 4AS, United Kingdom; Heriot-Watt University, Institute of Chemical Sciences, Edinburgh, EH14 4AS, United Kingdom; Scottish National Blood Transfusion Service (SNBTS), Jack Copland Centre, 52, United Kingdom
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