Paper Review Records
All Paper Review Records
10 valid samples · Newest publication first
Review days = acceptance date − received date. PDF, DOI, and publisher-page sources are retained.
A single-cell multi-omic atlas of the human pancreas reveals potential for cellular plasticity across development, health, and disease
AuthorsElisabetta Mereu; Diego Balboa; Johannes Liebig; Aitor Gonzalez-Herrero; Anna Martinez Casals; Mariya Mardamshina; Fanny Mollandin; Felix Schicktanz; Alexander Sudy; Luca Tosti; Maarten van Agen; Valerie Vandenbempt; Dana Avrahami; Frederic Ballllosera Navarro; Edgar Bernardo; Frida Björklund; Robert Lorenz Chua; Marten Engelse; Javier García-Hurtado; Nathalie Groen; Maaike Hanegraaf; Pablo Iañez; Katharina Jechow; Björn Konukiewitz; Christian Lawerenz; Nadja Lewandowski-Hoppe; Domenica Marchese; Mauro J. Muraro; Silvia Pellegrini; Valeria Sordi; Ulrike Taron; Foo Wei Ten; Timo Trefzer; Sven Twardziok; Johannes Wirth; Françoise Carlotti; Eelco de Koning; Jorge Ferrer; Benjamin Glaser; Holger Heyn; Emma Lundberg; Lorenzo Piemonti; Katja Steiger; Alexander van Oudenaarden; Wilko Weichert; Christian Conrad; Roland Eils
AffiliationsJosep Carreras Leukemia Research Institute, Barcelona, Spain; Centre for Genomic Regulation, the Barcelona Institute of Science and Technology, Dr. Aiguader 88, 08003 Barcelona, Spain; Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8, 00290 Helsinki, Finland; Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Digital Health Center, Charitéplatz 1, 10117 Berlin, Germany; Freie Universität Berlin, Berlin, Germany; Universitat de Barcelona, Barcelona, Spain; Department of Bioengineering, Stanford University, Stanford, CA, USA; Institute of Pathology, School of Medicine and Health, Technical University of Munich, Munich, Germany; Department of Internal Medicine, Leiden University Medical Center (LUMC), Leiden, the Netherlands; Department of Developmental Biology and Cancer Research, The Hebrew University-Hadassah Medical School, Jerusalem, Israel; Organ Crosstalk in Metabolic Diseases Group, Tumour Biology Programme, Centro Nacional Investigaciones Oncológicas (CNIO), Madrid, Spain; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, University Medical Center Utrecht, Utrecht, the Netherlands; Steinbeis Transfer GmbH, Center Health Data, Stuttgart, Germany; Comparative Experimental Pathology, Institute of Pathology, School of Medicine and Health, Technical University of Munich, Munich, Germany; Centro Nacional de Análisis Genómico (CNAG), Barcelona, Spain; Single Cell Discoveries, Utrecht, the Netherlands; Diabetes Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy; Section of Genetics and Genomics, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, UK; Department of Endocrinology and Metabolism, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel; ICREA, Barcelona, Spain; Università Vita-Salute San Raffaele, Milan, Italy; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and TUM University Hospital, Munich, Germany; Oncode Institute, Utrecht, the Netherlands; University Medical Center Utrecht, Utrecht, the Netherlands; Intelligent Medicine Institute, Fudan University, Shanghai, China
Beta2-adrenergic stimulation by fenoterol increases energy expenditure without activating human brown adipose tissue
AuthorsLaila Maria Füchtbauer; Jaël Rut Senn; Carole Stéphanie Baumann; Anninja Lea Isenrich; Taylah Lea Gaynor; Rahel Schläfli; Anand Kumar Sharma; Carla Horvath; Claudia Irene Maushart; Adhideb Ghosh; Kirsi A. Virtanen; Tobias Fromme; Alin Chirindel; Damian Wild; Søren Nielsen; Christian Wolfrum; Matthias Johannes Betz
AffiliationsDepartment of Endocrinology, Diabetes and Metabolism, University Hospital Basel and University of Basel, 4031 Basel, Switzerland; Centre for Physical Activity Research, Rigshospitalet, Section 7641, Blegdamsvej 9, 2100 Copenhagen, Denmark; The Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, 2200 Copenhagen N, Denmark; Laboratory of Translational Nutrition Biology, Institute of Food, Nutrition and Health, ETH Zürich, 8603 Schwerzenbach, Switzerland; Turku PET Centre, University of Turku, Turku, Finland; Turku PET Centre, Turku University Hospital, Turku, Finland; Molecular Nutritional Medicine, TUM School of Life Sciences, Technical University of Munich, EKFZ - Else Kröner-Fresenius Center for Nutritional Medicine, Freising, Germany; Division of Nuclear Medicine, University Hospital Basel and University of Basel, 4031 Basel, Switzerland
Maternal vitamin B12 deprivation exacerbates offspring obesity by reducing early-life colonization with Bifidobacterium pseudolongum
AuthorsZhaoyi Liu; Xiuwen Yang; Huaili Feng; Ting You; Fanwei Sun; Jianjiang Xue; Weijuan Liang; Jinwen Yao; Yi Liao; Yanan Gao; Yuanjun Yang; Xuejun Jiang; Qiang Zhang; Zhen Zou; Jun Zhang; Xinhao Duan; Jiao Wang; Qian Chen; Peng Su; Shangcheng Xu; Jingfu Qiu; Chengzhi Chen
AffiliationsDepartment of Health Laboratory Technology, College of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Department of Clinical Laboratory, University-Town Hospital of Chongqing Medical University, Chongqing 401331, People's Republic of China; Center of Experimental Teaching for Public Health, Experimental Teaching and Management Center, Chongqing Medical University, Chongqing 400016, People's Republic of China; Department of Occupational and Environmental Health, College of Public Health, Tianjin Medical University, Tianjin 300070, People's Republic of China; Molecular Biology Laboratory of Respiratory Disease, Key Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, People's Republic of China; Growth, Development, and Mental Health Center of Children and Adolescents, Children’s Hospital of Chongqing Medical University, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 401146, People's Republic of China; Environmental Exposure and Human Health, Chongqing Municipal Key Laboratory of Institutions of Higher Education, Chongqing Key Laboratory of Prevention and Treatment for Occupational Diseases and Poisoning, College of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China; Department of Occupational and Environmental Health, College of Public Health, Chongqing Medical University, Chongqing 400016, People's Republic of China
Competitive catabolism drives hyperglycemia and hyperinsulinemia in obesity
AuthorsDaniel R. Weilandt; Won Dong Lee; Michael R. MacArthur; Lingfan Liang; Corey D. Holman; Qingwei Chu; Alexis J. Cowan; Joseph A. Baur; Ned S. Wingreen; Joshua D. Rabinowitz
AffiliationsDepartment of Chemistry, Princeton University, Princeton University, Princeton, NJ, USA; Lewis-Sigler Institute of Integrative Genomics, Princeton University, Princeton University, Princeton, NJ, USA; Ludwig Institute for Cancer Research, Princeton Branch, Princeton University, Princeton, NJ, USA; Department of Molecular Biology, Princeton University, Princeton University, Princeton, NJ, USA; Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Biochemistry, Yonsei University, Seoul, South Korea
FGF21 synergizes with leptin to counteract obesity-related metabolic comorbidities by reversing hepatic leptin resistance
AuthorsQing Shen; Hailan Zou; Leigang Jin; Jiaxin Liu; Shixiang Wang; Na Li; Runhong Zhou; Ming Yue; Baile Wang; Ranyao Yang; Erfei Song; Yifen Lin; Songyan Liao; Zhiwei Chen; Yang Xiao; Yun-Shen Chan; Hung-Fat Tse; Aimin Xu
AffiliationsState Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong SAR, China; Department of Medicine, The University of Hong Kong, Hong Kong SAR, China; Guangdong-Hong Kong Joint Laboratory for Metabolic Medicine, The University of Hong Kong, Hong Kong SAR, China; National Clinical Research Center for Endocrine and Metabolic Diseases, Key Laboratory of Diabetes Immunology, Ministry of Education, Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China; Furong Laboratory, Central South University, Changsha 410008, Hunan Province, China; Guangzhou National Laboratory, Guangzhou International Bio Island, Guangzhou 510005, Guangdong Province, China; Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, Guangdong Province, China; The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 510150, Guangdong Province, China; The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China; Centre for Stem Cell Translational Biology, The University of Hong Kong, Hong Kong SAR, China; AIDS Institute and Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China; Institute of Metabolic Science, Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510005, Guangdong Province, China
Brown fat protects against hepatic oxidative stress by remodeling the circulating metabolome
AuthorsDandan Wang; Mark Li; Tian Lu; Mami Matsushita; Juro Sakai; Masayuki Saito; Takeshi Yoneshiro; Shingo Kajimura
AffiliationsDivision of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA; Department of Nutrition, School of Nursing and Nutrition, Tenshi College, Sapporo, Japan; Division of Molecular Physiology and Metabolism, Tohoku University Graduate School of Medicine, Sendai, Japan; Laboratory of Biochemistry, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan
AARS1 promotes tumor progression and immune evasion via ATF6 lactylation-mediated tryptophan metabolism in hepatocellular carcinoma
AuthorsYiming Wang; Fan Li; Jiongyuan Li; Tianning Huang; Tian Huang; Nan Zhang; Yiran Li; Ziyu Xun; Zhe Zhu; Qiaorui Tan; Xuanyu Zhao; Liangwei Zou; Mingjian Piao; Chengjie Li; Boyu Sun; Jingwen Ma; Pengyao Chen; Jian Gu; Shipeng Dai; Hao Wang; Ming Ni; Haitao Zhao; Ling Lu
AffiliationsHepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China; Department of Liver Surgery, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China; Jiangsu Key Laboratory of Organ Transplantation and Transplant Immunology and Hepatobiliary Center, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China; Research Unit of Liver Transplantation and Transplant Immunology, Chinese Academy of Medical Sciences, Nanjing 210029, China; Collaborative Innovation Center for Cancer Personalized Medicine and Hepatobiliary Center, Nanjing Medical University, Nanjing 211166, China; Center of Interventional Radiology & Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing 210009, China
Gut microbiota-derived lysine phenylacetylation impairs mitochondrial function and is alleviated by SIRT3
AuthorsWei Du; Jun-Yu Xu; Yufeng Li; Mingya Zhang; Yidan Huang; Shaoqian Zhao; Ying Zhou; Lei Zhao; Kexin Xu; Linhui Zhai; Wensi Zhao; Jia Liu; Jiahui Ni; Junxiao Dai; Tianxian Liu; Jie Hong; Haowen Jiang; Shuliang Zhao; Jian Zhang; Lu Zhou; Ji-Qiu Wang; Bin-Cheng Yin; Rui-Xin Liu; Jingya Li; Bang-Ce Ye; Minjia Tan
AffiliationsLaboratory of Biosystems and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan 528400, China; Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200020, China; University of Chinese Academy of Sciences, Beijing 100049, China; Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai 200434, China; Department of Urology, Huashan Hospital, Fudan University, Shanghai 200040, China; Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China; Department of Pharmaceutical and Artificial-Intelligence Sciences, Institute of Medical Artificial Intelligence, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; School of Pharmacy, Fudan University, Shanghai 201203, China
Methionine-supplemented longevity diet increases growth hormone, GLP-1, and FGF21; reduces frailty; and promotes healthspan
AuthorsMaura Fanti; Sebastian Brandhorst; Gerardo Navarrete; Arnold Diaz; Giacomo Giuliani; Dolly Chowdhury; Gabriel C. Antunes; Todd E. Morgan; Louis Dubeau; Valentina Villani; Laura Perin; Vasanti S. Malik; Frank B. Hu; Valter D. Longo
AffiliationsLongevity Institute, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA; Laboratory of Molecular Biology of Exercise, University of Campinas, Limeira, São Paulo, Brazil; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; GOFARR Laboratory, Children’s Hospital Los Angeles, Division of Urology, Saban Research Institute, Los Angeles, CA, USA; Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Nutritional Sciences, University of Toronto, Toronto, ON, Canada; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA
Oral GLP-1 receptor agonist promotes astrocyte-neuron lactate and lipid transfer with neuroprotective effects
AuthorsYixuan Du; Chujun Sun; Lingxi Wu; Zhongyun Wu; Yue Tong; Hong Tian; Yang Mao; Xupeiyao Shi; Haohui Ding; Wenbin Xie; Wenbing Yao; Song Chen; Xiangdong Gao
AffiliationsState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, China; Jiangsu Key Laboratory of Druggability of Biopharmaceuticals, School of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China
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