npj Precision Oncology

AuthorsAnni Köhler; Alexandra A. Baumann; Natasha Lewis; Anja Richter; Susan Richter; Doreen William; Andrés Cruz-García; Hanno Glimm; Stefan Fröhling; Diana Le Duc; Evelin Schröck; Arne Jahn

Affiliations1. Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden, Germany; 2. National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between German Cancer Research Center (DKFZ), Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany; 3. ERN-GENTURIS, Hereditary Cancer Syndrome Center, Dresden, Germany; 4. DKTK, Partner Site Dresden, Dresden, Germany; 5. Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany; 6. Institute for Medical Informatics and Biometry, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany; 7. Auckland Cancer Society Research Centre, School of Medical Sciences, University of Auckland, Auckland, New Zealand; 8. Core Unit for Molecular Tumor Diagnostics (CMTD), NCT/UCC Dresden, a Partnership between German Cancer Research Center (DKFZ), Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany; 9. Department for Translational Medical Oncology, National Center for Tumor Diseases (NCT/UCC) Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany; 10. Translational Medical Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany; 11. Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany; 12. National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg, Germany; 13. German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany; 14. Division of Translational Precision Medicine, Institute of Human Genetics, Heidelberg University, Heidelberg, Germany

AuthorsJulius Thyen; Victor A. Sioson; Daniel Haak; Beatrix Jahnke; Maximilian Fusenig; Abdul M. Aftab; Antonia Stammberger; Sascha Brückmann; Heike Polster; Stefanie Hübner; Verena J. Kast; Manuel Pfeifer; Rebecca Prause; Vivian Mittné; Carolin Beer; Malin H. Reinhart; Adrian M. Seifert; Lena Seifert; Martin Bornhäuser; Carsten Werner; Marc Schmitz; Daniela E. Aust; Jürgen Weitz; Daniela Loessner; Daniel E. Stange; Anna R. Poetsch; Mathieu Pecqueux; Franziska Baenke

Affiliations1. Department of Visceral, Thoracic and Vascular Surgery, Medical Faculty and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany; 2. Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials, Dresden, Germany; 3. Biomedical Genomics, Biotechnology Center, Center for Molecular and Cellular Bioengineering, TUD Dresden University of Technology, Dresden, Germany; 4. Institute of Immunology, Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany; 5. Institute of Pathology and Tumor- and Normal Tissue Bank of the University Cancer Center (UCC), University Hospital Carl Gustav Carus, Medical Faculty, TUD Dresden University of Technology, Dresden, Germany; 6. Institute of Legal Medicine, Medizinische Fakultät, TUD Dresden University of Technology, Dresden, Germany; 7. Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases Dresden (NCT/UCC), Dresden, Germany; 8. National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany; 9. German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany; 10. Else Kröner Clinician Scientist Professor for Translational Tumor Immunological Research, TUD Dresden University of Technology, Dresden, Germany; 11. Medical Clinic I, University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany; 12. Center for Regenerative Therapies Dresden (CRTD) and Cluster of Excellence Physics of Life (PoL), TUD Dresden University of Technology, Dresden, Germany; 13. Department of Chemical and Biological Engineering and Department of Materials Science and Engineering, Faculty of Engineering, Monash University, Melbourne, Australia; 14. Department of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia; 15. Institute for Genetics, University of Cologne, Cologne, Germany; 16. Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany; 17. Institute for Genome Stability in Aging and Disease, University of Cologne, Cologne, Germany

AuthorsAnna-Jasmina Donaubauer; Oliver Tomic; Lia Mogge; Sarina K. Müller; Cecilia Marie Futsaether; Kristian Hovde Liland; Bao Ngoc Huynh; Jens von der Grün; Panagiotis Balermpas; Max Fleischmann; Matthias G. Hautmann; Felix Steger; Christopher Bohr; Thomas Hehr; Carmen Stromberger; Volker Budach; Markus Schymalla; Rita Engenhart-Cabillic; Lukas Kocik; Hans Geinitz; Ursula Nestle; Gunter Klautke; Claudia Scherl; Philipp Schubert; Stefanie Corradini; Rainer Fietkau; Udo S. Gaipl; Benjamin Frey; Marlen Haderlein

Affiliations1. Translational Radiobiology, Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany; 2. Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany; 3. Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany; 4. Bavarian Cancer Research Center (BZKF), Erlangen, Germany; 5. Norwegian University of Life Sciences, Faculty of Science and Technology, Ås, Norway; 6. Department of Otolaryngology - Head & Neck Surgery, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany; 7. Department of Medical Physics, Oslo University Hospital, Oslo, Norway; 8. Department of Radiation Oncology, Zurich University Hospital, Zurich, Switzerland; 9. Department of Radiotherapy and Radiation Oncology, University Hospital Frankfurt, Goethe-Universität Frankfurt am Main, Frankfurt am Main, Germany; 10. Department of Radiotherapy and Radiation Oncology, University Hospital of Regensburg, Regensburg, Germany; 11. Department of Otorhinolaryngology, University Hospital Regensburg, Regensburg, Germany; 12. Department of Radiotherapy and Radiation Oncology, Marienhospital, Stuttgart, Germany; 13. Department of Radiotherapy and Radiation Oncology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; 14. Department of Radiotherapy and Radiation Oncology, University Hospital of Marburg, Marburg, Germany; 15. Department of Radiation Oncology and Radiotherapy, Ordensklinikum Linz Barmherzige Schwestern, Linz, Austria; 16. Faculty of Medicine, Johannes Kepler University Linz, Linz, Austria; 17. Department of Radiotherapy and Radiation Oncology, Kliniken Maria Hilf, Moenchengladbach, Germany; 18. Department of Radiation Oncology, Chemnitz Hospital, Chemnitz, Germany; 19. Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

AuthorsNicole Heinzl; Talayeh S. Ghezelayagh; Grace Wang; Brendan F. Kohrn; Ronit Katz; Coohleen Coombes; Thomas H. Smith; Zachary K. Norgaard; Fang Yin Lo; Elizabeth K. Schmidt; Jacob E. Higgins; Charles C. Valentine; Martin Filipits; Lou Romanens; Intidhar Labidi-Galy; Magdalena Postl; Christoph Grimm; David Cibula; Lukáš Dostálek; Filip Frühauf; Gabriel Jelenek; Magdalena Plch; Pavel Fabian; Alexander Mustea; Mateja Condic; Gunda Pristauz-Telsnigg; Karl Tamussino; Jiří Bouda; Christine E. Brambs; Sharon O’Toole; Katharina Bischof; Sabine Grill; Adam N. Rosenthal; Adriaan Vanderstichele; Peter Oppelt; T. Rinda Soong; Barbara M. Norquist; Jesse J. Salk; Robert Zeillinger; Paul Speiser; Rosa Ana Risques

Affiliations1. Department of Obstetrics and Gynaecology, Comprehensive Cancer Center - Gynaecologic Cancer Unit, Medical University of Vienna, Vienna, Austria; 2. Department of Obstetrics & Gynecology, Stanford University, Palo Alto, USA; 3. Department of Laboratory Medicine and Pathology, University of Washington, Seattle, USA; 4. Department of Obstetrics and Gynecology, University of Washington, Seattle, USA; 5. TwinStrand Biosciences, Seattle, USA; 6. Center for Cancer Research, Medical University of Vienna, Vienna, Austria; 7. Department of Oncology, Hôpitaux Universitaires de Genève, Genève, Switzerland and Center of Translational Research in Onco-Hematology, Faculty of Medicine, Université de Genève, Genève, Switzerland; 8. Department of Obstetrics and Gynecology, First Faculty of Medicine and General University Hospital, Prague, Czech Republic; 9. Department of Surgical Oncology, Department of Gynaecological Oncology, Masaryk Memorial Cancer Institute, Brno, Czech Republic; 10. Department of Pathology, Masaryk Memorial Cancer Institute, Brno, Czech Republic; 11. Department of Gynecology and Gynecologic Oncology, University Hospital Bonn, Bonn, Germany; 12. Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria; 13. Faculty of Medicine, Charles University, Pilsen, Czech Republic; 14. Department of Obstetrics and Gynecology, Luzerner Kantonsspital, Luzern, Switzerland; 15. Department of Obstetrics and Gynaecology/Histopathology, Trinity St James’s Cancer Institute, Dublin, Ireland; 16. Department of Cancer Immunology, Institute for Cancer Research, University of Oslo, Oslo, Norway; 17. Department of Surgical Oncology, Section of Gynaecological Oncology, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway; 18. Department of Gynecology and Obstetrics, University Hospital of the TU, Munich, Germany; 19. Familial Cancer Clinic, Department of Gynaecology, University College London Hospitals NHS Trust, London, UK; 20. Department of Women’s Cancer, Elizabeth Garett Anderson Institute for Women’s Health, University College London, London, UK; 21. Department of Obstetrics and Gynecology, Catholic University Leuven, Leuven, Belgium; 22. Department of Gynaecology, Obstetrics, and Gynaecologic Endocrinology, Johannes Kepler University Linz, Kepler University Hospital, Linz, Austria; 23. Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, USA; 24. Division of Hematology and Oncology, University of Washington, Seattle, USA

AuthorsBenjamin Heckelmann; Daniel Fetzner; Olga Lapshyna; Ashinikumar Singh Hidam; Annika Brauer; Anna Maxi Wandmacher; Benedikt Färber; Jannis Duhn; Meike ten Winkel; Louisa Bolm; Kim Honselmann; Steffen Deichmann; Christoph Röcken; Darko Carstven; Jens Marquardt; Corinna Keber; Timo Gemoll; Susanne Sebens; Tobias Keck; Ulrich Wellner; Rüdiger Braun

Affiliations1. Department of Surgery, University of Luebeck, Luebeck, Germany; 2. Institute for Experimental Tumor Research, Kiel University, University Hospital Schleswig-Holstein, Kiel, Germany; 3. Department of Internal Medicine II, Division of Hematology and Oncology, University Hospital Schleswig-Holstein, Kiel, Germany; 4. Department of Hematology and Oncology, University of Luebeck, Luebeck, Germany; 5. Institute of Pathology, Kiel University, University Hospital Schleswig-Holstein, Kiel, Germany; 6. Department of Internal Medicine I, University of Luebeck, Luebeck, Germany; 7. Institute of Pathology, University Hospital of Giessen-Marburg, Marburg, Germany

AuthorsLei Zhang; Jun Li; Mu Li; Lanlan Guo; Jing Zhang; Ling Liu; Zhenglun Yu

Affiliations1. Department of Breast Surgery, The First Hospital of China Medical University, Shenyang, China; 2. Department of Ophthalmology, The First Hospital of China Medical University, Shenyang, China; 3. Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, China; 4. Department of Ultrasound, The Fourth Affiliated Hospital of China Medical University, Shenyang, China; 5. Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China; 6. Department of Gynecology, The Fourth Affiliated Hospital of China Medical University, Shenyang, China; 7. Department of Thoracic Surgery, The First Hospital of China Medical University, Shenyang, China

AuthorsLucas Werner; Parisa Esmaeili; Ella Ittner; Hugo Swenson; Anikó Kovács; Claudia Mateoiu; Pernilla Dahm-Kähler; Per Karlsson; Toshima Parris; Fredrik Levander; Khalil Helou

Affiliations1. Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 2. Sahlgrenska Center for Cancer Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 3. Department of Immunotechnology, Science for Life Laboratory, Lund University, Lund, Sweden; 4. Department of Clinical Pathology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden; 5. Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 6. Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; 7. Department of Oncology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden

AuthorsBranko Calukovic; Katrin Benzler; Henning Zelba; Christian Seitz; Simone Kayser; Magdalena Feldhahn; Borong Shao; Martin Schulze; Olga Maksimovic; Veit Scheble; Florian Battke; Lars Zender; Ulrich M. Lauer; Saskia Biskup; Christoph K. W. Deinzer

Affiliations1. Department of Internal Medicine VIII - Medical Oncology and Pneumology, University Hospital Tübingen, Tübingen, Germany; 2. Center for Soft Tissue Sarcomas, GIST and Bone Tumors (ZWS) of the University Hospital Tübingen and the Comprehensive Cancer Center (CCC) Tübingen-Stuttgart, Tübingen, Germany; 3. DFG Cluster of Excellence 2180 ‘Image-Guided and Functional Instructed Tumor Therapy’ (iFIT), University of Tübingen, Tübingen, Germany; 4. Center for Human Genetics Tübingen, Tübingen, Germany; 5. Hopp Children’s Cancer Center Heidelberg (KiTZ), Heidelberg University Hospital and German Cancer Research Center (DKFZ), Heidelberg, Germany; 6. Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany; 7. Department of General Pediatrics, Hematology and Oncology, University Children’s Hospital, Tübingen, Germany; 8. CeGaT GmbH, Tübingen, Germany; 9. MVZ Oncology Tübingen, Tübingen, Germany; 10. German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Tübingen, Germany

AuthorsGreta Gudoityte; Olena Berkovska; Lukas M. Orre; Elisabeth Moussaud-Lamodière; Rebecka Bergström; Johan Lindberg; Martin Haraldsson; Sacha Bou Nafeh; Méline Louhaur; Olli Kallioniemi; Josefin Fernebro; Ulrika Joneborg; Brinton Seashore-Ludlow

Affiliations1. Science for Life Laboratory (SciLifeLab), Karolinska Institutet, Stockholm, Sweden; 2. Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden; 3. Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden; 4. Department of Gynecology and Reproductive Medicine, Karolinska University Hospital, Stockholm, Sweden; 5. Department of Molecular Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; 6. Chemical Biology Consortium Sweden, Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden; 7. Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; 8. Department of Pelvic Cancer, Karolinska University Hospital, Stockholm, Sweden; 9. Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden

AuthorsArvid Cederlund; Nona Struyf; Lucia Rico Pizarro; Päivi Östling; Kristina Sonnevi; Björn Engelbrekt Wahlin; Tom Erkers

Affiliations1. Dept. of Medicine at Huddinge, Karolinska Institutet, Stockholm, Sweden; 2. Medical Unit Hematology at Solna, Cancer, Karolinska University Hospital, Stockholm, Sweden; 3. Department of Oncology-Pathology, Karolinska Institutet and Science for Life Laboratory, Stockholm, Sweden