NATURE METHODS

AuthorsJulio Saez-Rodriguez; Philipp Sven Lars Schäfer; Nikolas Kalavros; Gustavo Stolovitzky

Affiliations1. European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK; 2. Institute for Computational Biomedicine, Heidelberg University, Faculty of Medicine and Heidelberg University Hospital, Heidelberg, Germany; 3. Department of Pathology, NYU Grossman School of Medicine, New York, USA; 4. Biomedical Data Science Hub, NYU Langone Health, New York, USA

AuthorsLieke Michielsen; Andrey D. Prjibelski; Careen Foord; Yelizaveta Spiegelman; Taewoo Kim; Wen Hu; Julien Jarroux; Justine Hsu; Rebecca Pfeil; Xinyi Zhang; Li Gan; Alexandru I. Tomescu; Iman Hajirasouliha; Hagen U. Tilgner

Affiliations1. Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, USA; 2. Center for Neurogenetics, Weill Cornell Medicine, New York, USA; 3. Department of Systems and Computational Biomedicine, Weill Cornell Medicine of Cornell University, New York, USA; 4. Caryl and Israel Englander Institute for Precision Medicine, The Meyer Cancer Center, Weill Cornell Medicine, New York, USA; 5. Department of Computer Science, University of Helsinki, Helsinki, Finland; 6. Helen and Robert Appel Alzheimer’s Disease Research Institute, Weill Cornell Medicine, New York, USA; 7. Department for Endocrinology and Diabetology, Medical Faculty and University Hospital Düsseldorf, Düsseldorf, Germany; 8. German Diabetes Center (DDZ), Leibniz Institute for Diabetes Research, Düsseldorf, Germany; 9. Center for Digital Medicine, Heinrich Heine University Düsseldorf, Düsseldorf, Germany

AuthorsJames Joly; Vivekananda Budamagunta; Zhengjian Zhang; Brittany Nortman; Maryam Jouzi; Rajat Bhatnagar; Jarrett D. Egertson; Michael E. Flaster; Rob Grothe; Sanjib Guha; Kota Kaneshige; Kevin McVey; Nicholas Nelson; Rukshan T. Perera; Steven J. Tan; Tuan Trinh; David Arnott; Joanna Lipka; Nikhil J. Pandya; Lionel Rougé; Timothy J. Wendorff; Donald S. Kirkpatrick; Alexis Rohou; David C. Butler; Steven Lotz; Ana Forton; Emily R. Sartori; Jessica E. Schwarz; Phillip S. Brereton; Kevin Chen; Michael A. Darcy; Hamid R. Golnabi; Ross Hartley; Pierre F. Indermuhl; Christina E. Inman; Kevin M. Jin; Stanislav Katsyuk; Rajesh Kota; Bryant Lowry; Jonathan C. Menger; Denise A. Miller; Maureen R. Newman; Adedeji Ogunyemi; Julia K. Robinson; Noah Steiner; Juanfeng Sun; Scott M. Tabakman; Lisen Wang; Zhiqiang Wang; Sheri K. Wilcox; Gregory T. Kapp; Sujal Patel; Sally Temple; Taylor Bertucci; Joel Blanchard; Andreas F. R. Huhmer; Subramanian V. Sankar; Kara Juneau; Parag Mallick

Affiliations1. Nautilus Biotechnology, San Carlos, USA; 2. Genentech, South San Francisco, USA; 3. Neural Stem Cell Institute, Albany, USA; 4. The Ronald Loeb Center for Alzheimer’s Disease at Mt. Sinai, New York, USA; 5. Stanford University School of Medicine, Palo Alto, USA

AuthorsYajuan Li; Zhaojun Zhang; Archibald Enninful; Negin Farzad; Presha Rajbhandari; Hua Tian; Jungmin Nam; Xiaoyu Qin; Jorge Villazon; Anthony A. Fung; Hongje Jang; Zhiliang Bai; Nancy R. Zhang; Brent R. Stockwell; Rong Fan; Mina L. Xu; Zongming Ma; Lingyan Shi

Affiliations1. Shu Chien-Gene Lay Department of Bioengineering, University of California, University of California, San Diego, La Jolla, USA; 2. Department of Statistics and Data Science, Wharton School, University of Pennsylvania, Philadelphia, USA; 3. Department of Biomedical Engineering, Yale University, New Haven, USA; 4. Department of Chemistry, Columbia University, New York, USA; 5. Department of Biological Sciences, Columbia University, New York, USA; 6. Environmental and Occupational Health, Pitt Public Health, Pittsburgh, USA; 7. Children’s Neuroscience Institute, School of Medicine, Pittsburgh, USA; 8. Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, USA; 9. Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, USA; 10. Department of Pathology, Yale School of Medicine, New Haven, USA; 11. Yale Cancer Center, Yale School of Medicine, New Haven, USA; 12. Yale Stem Cell Center, Yale School of Medicine, New Haven, USA; 13. Yale Center for Research on Aging (Y-Age), Yale School of Medicine, New Haven, USA; 14. Department of Statistics and Data Science, Yale University, New Haven, USA

AuthorsMatthew C. Jenkins; Daija Bobe; Jake D. Johnston; Jonah Cheung; Akira Karasawa; Christina M. Zimanyi; Ömer Dermanci; Collin T. McManus; M. G. Finn; Alex de Marco; Mykhailo Kopylov

Affiliations1. School of Chemistry and Biochemistry, School of Biological Sciences, Georgia Institute of Technology, Atlanta, USA; 2. Simons Electron Microscopy Center, New York Structural Biology Center, New York, USA; 3. Department of Physiology and Cellular Biophysics, Columbia University, New York, USA; 4. Department of Biochemistry and Biophysics, Columbia University, New York, USA; 5. CZI Biohub, Redwood City Site, Redwood City, USA

AuthorsJieran Sun; Kirti Biharie; Peiying Cai; Niklas Müller-Bötticher; Paul Kiessling; Meghan A. Turner; Søren Helweg Dam; Florian Heyl; Sarusan Kathirchelvan; Martin Emons; Samuel Gunz; Sven Twardziok; Amin El-Heliebi; Martin Zacharias; Roland Eils; Marcel Reinders; Raphael Gottardo; Christoph Kuppe; Brian Long; Ahmed Mahfouz; Mark D. Robinson; Naveed Ishaque

Affiliations1. Biomedical Data Science Center, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; 2. Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands; 3. Delft Bioinformatics Lab, Delft University of Technology, Delft, the Netherlands; 4. Department of Molecular Life Sciences and SIB Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland; 5. Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Center of Digital, Berlin, Germany; 6. Department of Nephrology, Rheumatology, and Clinical Immunology, University Hospital RWTH Aachen, Aachen, Germany; 7. Allen Institute for Brain Science, Seattle, USA; 8. DTU Health Tech, Technical University of Denmark, Ørsteds Plads, Kongens Lyngby, Denmark; 9. LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark; 10. German Cancer Research Center (DKFZ), Division of Computational Genomics and Systems Genetics, Heidelberg, Germany; 11. The German Human Genome-Phenome Archive, Heidelberg, Germany; 12. Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria; 13. Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria

AuthorsHendrik A. Michel; Paige McCallum; Wenrui Wu; Huaying Qiu; Jia Le Lee; Shuli Luo; Chi Ngai Chan; Johanna Schaffenrath; Yao Yu Yeo; Stephanie Pei Tung Yiu; Yang Wang; Lindsay Parmelee; Hongbo Wang; Tania Pannellini; Melinda Burgess; Nourhan El Ahmar; Zoe Xiaozhu Zhang; Colm Keane; Tony Kiat Hon Lim; Sabina Signoretti; Sonia Victoria Del Rincon; Bo Zhao; David R. McIlwain; Yunhao Bai; Fei Chen; Roberto Chiarle; Sizun Jiang

Affiliations1. Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA; 2. Program in Virology, Division of Medical Sciences, Harvard Medical School, Boston, USA; 3. Division of Clinical and Translational Research, McGill University, Montréal, Canada; 4. Division of Infectious Diseases, Department of Medicine, Brigham and Women’s Hospital, Boston, USA; 5. Division of Hematopathology, IEO European Institute of Oncology IRCCS, Milan, Italy; 6. Frazer Institute, Translational Research Institute, University of Queensland, Brisbane, Australia; 7. Department of Pathology, Brigham and Women’s Hospital, Boston, USA; 8. Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore; 9. Department of Microbiology and Immunology, University of Nevada Reno, Reno, USA; 10. Broad Institute of Harvard and MIT, Cambridge, USA; 11. Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, USA; 12. Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy

AuthorsAriana Peck; Joshua Hutchings; Jonathan Schwartz; Yue Yu; Utz H. Ermel; Saugat Kandel; Dari Kimanius; Zhuowen Zhao; Shawn Zheng; Brendan Artley; David List; Sergio A. Silva; Walter Reade; Jeremy Asuncion; Kira Evans; Jessica Gadling; Kandarp Khandwala; Suzette McCanny; Dannielle G. McCarthy; Jun Xi Ni; Janeece Pourroy; Manasa Venkatakrishnan; Zun Shi Wang; David A. Agard; Clinton S. Potter; Bridget Carragher; Kyle I. S. Harrington; Mohammadreza Paraan

Affiliations1. Biohub, Redwood City, USA; 2. Unaffiliated, Vancouver, Canada; 3. Unaffiliated, Denver, USA; 4. Department of Informatics, State University of Maringá, Maringá, Brazil; 5. Kaggle/Google, Mountain View, USA; 6. Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, USA

AuthorsTalal Widatalla; Ashir A. Borah; Samuel H. King; Claudia L. Driscoll; Rafael Rafailov; Brian L. Hie

Affiliations1. Stanford University, Stanford, USA; 2. Arc Institute, Palo Alto, USA; 3. University of California, San Francisco, San Francisco, USA

AuthorsLuca Deininger; Paolo Caldarelli; Magdalena Zernicka-Goetz; Ralf Mikut

Affiliations1. Group for Automated Image and Data Analysis, Institute for Automation and Applied Informatics, Karlsruhe Institute of Technology, Eggenstein‑Leopoldshafen, Germany; 2. Division of Pediatric Neurology and Metabolic Medicine, Department I, Center for Pediatric and Adolescent Medicine, Medical Faculty Heidelberg, Heidelberg University, Heidelberg, Germany; 3. Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland; 4. Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, USA