医学
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TUG-891-mediated FFAR4 activation attenuates vascular remodeling via suppression of aberrant browning and lipolysis in perivascular adipose tissue
作者Ai Jiang; Tianjiao Wang; Xiaobing Xu; Zhang Chen; Yujuan Li; Jiahe Du; Yixuan Jiang; Xinzhi Li
作者单位School of Pharmacy, Faculty of Medicine & Laboratory of Drug Discovery from Natural Resources and Industrialization, Macau University of Science and Technology, Taipa, Macao, China; State Key Laboratory of Mechanism and Quality of Chinese Medicine, Macau University of Science and Technology, Taipa, Macao, China
Aquaporin-1 facilitates the transport of hydrogen peroxide and nitric oxide during endothelium-dependent vasorelaxation
作者Omar Echeverría Rodríguez; Sebastián Ramírez Rodríguez; Sara Daniela Hernández Torres; Héctor Riveros Rosas; Itzell A. Gallardo Ortíz; Rafael Villalobos Molina; María Magdalena Vilchis Landeros
作者单位Department of Biochemistry, Faculty of Medicine, Universidad Nacional Autónoma de México, Coyoacán, 04510 Mexico City, Mexico; Division of Research and Postgraduate Studies, Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, 54090, State of Mexico, Mexico
Pan-peroxisome proliferator-activated receptor agonist IVA337 alleviates secondary lymphedema via inhibiting TGFβ/SMAD2/3 signaling pathway
作者Jingjing Pang; Long Nguyen Hoang Do; Esteban Delgado; Jianan Zhao; Liam Flynn; Hongxia Liu; Michael Autieri; Xiaofeng Yang; Xiaolei Liu
作者单位Lemole Center for Integrated Lymphatics and Vascular Research, United States of America
Multi-omics and experimental validation reveal the proliferative mechanism of ACSL4 in pulmonary hypertension and identify potential FDA-approved drugs via in silico screening
作者Wei Chen; Yiting Dong; Qihao Shi; Hongbing Meng; Jiawei Sun; Congmei Han; Chenjie Yan; Chendong Wu; Jing Wang; Adriana Georgescu; Keke Jin; Linbo Yuan
作者单位Wenzhou Medical University, Wenzhou, China; Renji College, Wenzhou Medical University, Wenzhou 325000, China; Xinjiang General Station of Exit and Entry Frontier Insp, Xinjiang, China; Department of Pathophysiology, School of Basic Medical Science, Wenzhou Medical University, Wenzhou, China; Department of Physiology, School of Basic Medical Science, Wenzhou Medical University, Wenzhou, China; Department of Pathophysiology and Cellular Pharmacology, Institute of Cellular Biology and Pathology ‘Nicolae Simionescu’ of Romanian Academy, Bucharest, Romania
Formoterol fumarate attenuates atherosclerosis and improves cardiometabolic dysfunction in ApoE-deficient mice
作者Havyarimana Juvenal; Wenjiao Gu; Zhihui Zhao; Yunqi Pan; Youming Shi; Shuangyi Li; Ying Jiang; Mohamed Ali Awad; Sijing Chen; Yunyang Zhao; Xiaochun Zhou; Futian Tang
作者单位The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, Gansu Province, China; Department of Cardiovascular Disease, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China; The First Clinical Medical College of Lanzhou University, Lanzhou 730030, China; School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu Province, China; Department of Nephrology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China; Gansu Province Key Laboratory of Environmental Oncology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China
Novel application of paeoniflorin: Stabilization of atherosclerotic plaques via the AMPK/PPARδ signaling pathway
作者Jiqian He; Jiali Liu; Zhensen Zheng; Faxin Fan; Zhizhong Luo; Duosheng Luo
作者单位Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Key Laboratory of Glucolipid Metabolic Disorder, Ministry of Education of China, China; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangdong TCM Key Laboratory for Metabolic Diseases, Guangzhou 510006, China
Multiple manifestations of coronary microvascular dysfunction in a double-hit mouse model of HFpEF
作者Grzegorz Kwiatkowski; Urszula Tyrankiewicz; Sylwester Mosiołek; Anna M. Gdula; Marek Grosicki; Agata Jędrzejewska; Barbara Kutryb-Zając; Izabela Czyzynska-Cichon; Agnieszka Zakrzewska; Agnieszka Jasztal; Greetje Vande Velde; Stefan Chłopicki
作者单位Jagiellonian University, Jagiellonian Centre for Experimental Therapeutics (JCET), Krakow, Bobrzynskiego 14, Poland; Jagiellonian University, Doctoral School of Exact and Natural Sciences, Krakow, Lojasiewicza 11, Poland; Medical University of Gdańsk, Department of Biochemistry, Gdańsk, Poland; Medical University of Gdańsk, Centre for Experimental Cardiooncology, Gdańsk, Poland; KU Leuven, Department of Imaging and Pathology, Biomedical MRI Unit, Leuven, Belgium; Jagiellonian University Medical College, Faculty of Medicine, Chair of Pharmacology, Krakow, Poland
circFBXO7 promotes ferroptosis in vascular endothelial cells exposed to high glucose through enhancing proteasomal degradation of TFCP2
作者Chenyang Qiu; Tianchi Chen; Zhengyuan Fang; Ruoran Lin; Zhenpeng Yuan; Shilong Sun; Jiawei Fu; Yanbo Lou; Wei Lu; Ziheng Wu
作者单位Department of Vascular Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Department of Vascular, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, China, 322000; Department of Cardiovascular Surgery, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, China
Role of the Elastase-2 (Ela-2)/OPN-N cascade in abdominal aortic aneurysm pathobiology: A human-to-mouse translational study
作者Fabiola Mestriner; Vinicius Flora Dugaich; Henrique Z. Kovacs; Pedro Bruch Dantas; Jessyca Michelon-Barbosa; Carlos A.C. Corsi; Maria Cecília Jordani; Pedro Vargas Pinilla; Warlen P. Piedade; Edwaldo E. Joviliano; Maurício Serra Ribeiro; Christiane Becari
作者单位Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil; Department of Medicine, Bauru Medical School, University of São Paulo, Bauru, São Paulo, Brazil; Department of Biological Science, School of Dentistry of Bauru, University of São Paulo, Bauru, São Paulo, Brazil
Brain cells neuroprotection induced by TNF-α and LRP5
作者Noelia Pimentel; Aureli Luquero; Xiangjun Li; Lina Badimon; Gemma Vilahur; Maria Borrell-Pages
作者单位Molecular Pathology and Therapeutic of Ischemic and Atherothrombotic Diseases, Institut de Recerca Sant Pau (IR SANT PAU), Sant Quintí 77-79, 08041 Barcelona, Spain; Biomedicine Doctorate Program, Universitat de Barcelona, Barcelona, Spain; Biochemistry, Molecular Biology and Biomedicine Doctorate Program, Universitat Autonoma de Barcelona, Spain; CIBER-CV, Instituto de Salud Carlos III, Madrid, Spain
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