医学
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Pan-cancer screening and integrative multi-omics and deep learning reveal the prognostic significance of an IBD-CRC shared host–microbe signature in bladder urothelial carcinoma
作者Changxin Zhan; Ting Xu; Hongshen Lai; Yifeng He; Fengjie Chen; Ruijian Liu; Bangqi Wang; Zhu Wang; Hui Liang; Deqin Zeng
作者单位Department of Urology, The People’s Hospital of Longhua Shenzhen, 38 Jinglong Jianshe Road, Longhua District, Shenzhen, Guangdong, 518109, China; Department of Urology, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, 466 Xingang Middle Road, Haizhu District, Guangzhou, Guangdong, 510317, China; General Management Department, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, 290 Jichang Road, Baiyun District, Guangzhou, Guangdong, 510410, China; Minimally Invasive Hyperhidrosis Center, The Affiliated Guangdong Second Provincial General Hospital of Jinan University, 466 Xingang Middle Road, Haizhu District, Guangzhou, Guangdong, 510317, China
FABP4 characterizes metabolic–immune interactions and serves as a prognostic biomarker across gynecologic malignancies: a multi-omics integrative analysis
作者Fangfang Chen; Lifeng Dong; Saisa Zhu; Zhiyuan Bo; Yangfan Fan; Yizhou Huang; Yiding Chen; Fang Wan
作者单位Department of Breast Surgery, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Department of Breast Surgery, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
A multi-stage prospective study evaluates serum metabolomic signatures for the differential diagnosis and prognostic stratification of PDAC
作者Zhouyu Ning; Ying Zhu; Hui Li; Zhiqiang Meng
作者单位Department of Minimally invasive therapy center, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China; Department of Integrative Oncology, Fudan University Shanghai Cancer Centre, Shanghai, China
In vivo and FACS-based CRISPR/Cas9 screening uncovers VENTX as a crucial element in maintaining seminoma stemness
作者Chaoxiong Huang; Yiran Chen; Enhuan Zhang; Yifan Wang; Yixuan Liu; Lirui Tang; Chuanben Chen; Peicheng Lin; Bingyi Wang
作者单位Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, 350014, China; Anxi County Hospital, Quanzhou, 362400, China
Dinutuximab beta with TEMIRI chemotherapy in relapsed/refractory neuroblastoma: Real-world insights into the open question of GD2 expression
作者Maria Antonietta De Ioris; Francesca Del Bufalo; Concetta Quintarelli; Valentina Bertaina; Francesco Fabozzi; Maria Giuseppina Cefalo; Iside Alessi; Chiara Grimaldi; Maria Felicia Villani; Maria Luisa D’Andrea; Alessandra Stracuzzi; Claudio Altini; Carmen Malaspina; Matilde Sinibaldi; Stefano Di Cecca; Laura Iaffaldano; Clelia Geraci; Marco Becilli; Biagio De Angelis; Alessandro Crocoli; Giulia Cassanelli; Stefano Margaritora; Angela Mastronuzzi; Franco Locatelli
作者单位Pediatric Hematology and Oncology, Cell and Gene Therapy, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy; Surgical Oncology Unit, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy; Nuclear Medicine Unit, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy; Radiology Unit, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy; Pathology Unit, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy; Thoracic Surgery, Catholic University of the Sacred Heart, Rome, Italy; Department of Life Sciences and Public Health, Catholic University of the Sacred Heart, Rome, Italy
A multi-temporal MRI radiomics model for early post-ablation recurrence risk stratification in hepatocellular carcinoma
作者Yihang Xu; Liting Peng; Junbin Liao; Zixin Huang; Shiyi Liu; Shuo Wang; Yuxi Huang; Xiaofei Qu; Manxia Lin; Jingxian Shen; Ruiming Liang
作者单位Division of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Division of Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China; Department of Imaging Diagnosis and Interventional Center, Sun Yat-sen University Cancer Center, Guangzhou, China; State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine, Guangdong Provincial Clinical Research Center for Cancer, Guangdong Esophageal Cancer Institute, Guangzhou, China; Department of Medical Statistics, Clinical Trials Unit, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
A chemoresistance-associated proliferation gene signature identified by single-cell and machine learning analysis predicts prognosis in high-grade serous ovarian carcinoma
作者Yanmin Zhang; Sihuang Wu; Huizhu Lin; Ling Li
作者单位Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China; Henan Gynecological Diseases (Gynecology Oncology) Clinical Research Center, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou 450014, China; Cell-Gene Therapy Translational Medicine Research Centre, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, China; Biotherapy Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, China; Department of Gynecology and Obstetrics, High-Risk Perinatal Medicine Center, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China
Cancer-associated fibroblasts-derived CAV1 promotes epithelial-mesenchymal transition and stemness in bladder cancer through activation of the LIF/STAT3 signaling pathway
作者Qi Wang; Dengdian Wang; Haihong Jiang; Jie Min; Lin Hu; Jiatong Yin; Xiansheng Zhang
作者单位Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China; Department of Urology, the Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China; Central Operating Room, the Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China; Anhui Medical University, Hefei, 230032, China
CLDN18 as a novel junctional biomarker enhancing multi-gene classification of pancreatic cancer
作者Jessie Santoro; Lisa Agnello; Andrea Colacino; Ilaria Leone; Joel Verísimo-García; Eleonora Viscusi; Stefano Laudati; Giuseppe Iannaci; Antonio D’Antonio; África González-Fernández; Valentina De Falco; Immacolata Maietta
作者单位IRCCS SYNLAB SDN, Via Galileo Ferraris 144, 80146 Naples, Italy; CINBIO, Immunology Group, Universidade de Vigo 36310 Vigo, Spain; Instituto de Investigación Sanitaria Galicia Sur (IIS Galicia Sur), SERGAS-UVIGO, 36312, Vigo, Spain; UO.C. Anatomia Patologica, P.O. Pellegrini ASL NA1 Centro, 80134, Naples, Italy; UO.C. Anatomia Patologica, Ospedale del Mare ASL NA1 Centro, 80147, Naples, Italy; Institute of Endotypes in Oncology Metabolism and Immunology “G. Salvatore” (IEOMI-CNR), 80131 Naples, Italy
Clinicopathologic and molecular features of primary effusion lymphoma and fluid overload-associated large B-cell lymphoma: A retrospective study
作者Taesung Jeon; Young-Hyeh Ko; You-Na Sung; Harim Oh; Hyunsung Kim; Seongsik Bang; Ka-Won Kang; Changgon Kim; Kunye Kwak; Yeseul Kim; Sangjeong Ahn
作者单位Department of Pathology, Korea University College of Medicine, Guro Hospital, Seoul, 08308, Republic of Korea; Department of Pathology, Cheju Halla General Hospital, Jeju, 63092, Republic of Korea; Department of Pathology, Korea University College of Medicine, Anam Hospital, Seoul, 02841, Republic of Korea; Department of Pathology, Hanyang University College of Medicine, Seoul, 04763, Republic of Korea; Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, 03181, Republic of Korea; Division of Hematology-Oncology, Department of Internal Medicine, Korea University College of Medicine, Seoul, 02841, Republic of Korea
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