医学
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Sodium valproate at concentrations bracketing estimated seminal plasma levels impairs human sperm function in vitro through oxidative stress and mitochondrial dysfunction
作者Zhen Peng; Zuoao Shi; Xin Zhang; Yimin Cheng
作者单位Yichun People's Hospital, Yichun, Jiangxi Province 336000, China; College of Pharmacy, Yichun University, Yichun 336000, China; Clinical Medical College, Yichun University, Yichun 336000, China; College of Basic Medicine, Yichun University, Yichun 336000, China
Potent inhibition and limited reactivation of human cholinesterases by cholesterol- and quinoline-based oximes
作者Petra Tuksar; Goran Šinko; Matea Kurtović Kodžoman; Maja Katalinić; Mireia Toledano-Pinedo; Mourad Chioua; José Marco-Contelles; Zrinka Kovarik
作者单位Division of Toxicology, Institute for Medical Research and Occupational Health, Zagreb, Croatia; Institute of General Organic Chemistry (CSIC), Madrid, Spain; Department of Chemistry, Faculty of Science, University of Zagreb, Zagreb, Croatia
Probing human tubulins–phomopsins interaction: An in silico approach for a mechanism-based hazard prioritisation of the phomopsin family
作者Ilaria Magnaldi; Lucy May Carr; Lorenzo Pedroni; Jean-Lou C.M. Dorne; Luca Dellafiora
作者单位Department of Food and Drug, University of Parma, Parma, Italy; European Food Safety Authority, Parma 43126, Italy
Transfluthrin: A household insecticide alters glucose metabolism, mitochondrial function and induces atrophy in C2C12 myotubes
作者Onkar Sharma; Rumi Devi; Sachin Sharma; Anita Dua; Sanjeev Gupta; Ashwani Mittal
作者单位Skeletal Muscle Lab, Institute of Integrated & Honors Studies, Kurukshetra University, Kurukshetra, Haryana 136119, India; Department of Pharmacology, School of Pharmaceutical Sciences, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh 173229, India
When safe is not safe together: Co-exposure to individually sub-cytotoxic compounds alters functional integrity of HepG2-derived liver 3D spheroids
作者Mohammad Ghasemzadeh-Hasankolaei; Scott McCormick; Léa Magne; Nihal Engin Vrana; Amir M. Ghaemmaghami
作者单位Immunology & Immuno-bioengineering Group, School of Life Sciences, University of Nottingham, University Park, Nottingham, UK; Spartha Medical SAS, Strasbourg, France
Titanium dioxide nanoparticles induce neurotoxicity through PI3K/Akt-mediated mitochondrial apoptosis
作者Zhibing Zhang; Yanyan Fang; Shuang Chen; Kun Peng; Xiang Gao; Jingdong Zhang; Qinyu Peng; Shangqi Sun; Danhao Xia; Lanxia Meng; Qihu Zhu; JiaHong Lu; Fei Li; Zhentao Zhang; Chaoyang Liu
作者单位Research Center for Environment and Health, Zhongnan University of Economics and Law, Wuhan 430073, China; Department of Neurology, Renmin Hospital of Wuhan University, Wuhan 430060, China; State Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, SAR, Macao 999078, China
The role of Mfn2/PERK- mediated ER-mitochondrial communication in autophagy induced by silica nanoparticles in HT22 cells
作者Tiantian Tian; Yuanyuan Zhang; Xinyue Li; Jia Zhang; Ying Hao; Huiyuan Hu; Kai Ma; Mingqian Wang; Wei Quan; Haiying Du; Minghua Jin
作者单位School of Public Health Jilin University, Changchun,Jilin 130021, PR China; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun 130062, China; Department of Neurology, China–Japan Union Hospital of Jilin University, No. 126, Xin Tai Road, Changchun, Jilin 130021, China
Hepatocyte necroptosis triggers macrophage NOD-like receptor family pyrin domain-containing 3 inflammasome activation in N, N-dimethylformamide-induced liver injury
作者Xiu-Ning Zhang; Jing-Jing Chen; Shuo Wang; Yan-Jing Zhang; Wei-Ru Wang; Tao Zeng
作者单位Institute of Toxicology. School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China; Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan 250062, China; Qingdao Public Health Clinical Center, Qingdao, Shandong, China; State Key Laboratory of Macromolecular Drugs and Large-scale Preparation, School of Pharmaceutical Sciences and Food Engineering, Liaocheng University, Liaocheng, Shandong 252059, China; Institute of Toxicology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China; Ministry of Emergency Management, Jinan Municipal Center for Disease control and prevention, Jinan, Shandong 250021, China; Institute of Toxicology. School of Public Health, Cheeloo College of Medicine, Shandong University, China
Alox12 mediates the temporal shift of arsenite-induced ferroptosis in zebrafish embryonic fibroblast ZF4 cells
作者Yu Wang; Xu Han; Zizheng Wang; Yushan Song; Yiqiang Zhang; Mingwei Xing; Hongjing Zhao
作者单位College of Wildlife and Protected Area, Northeast Forestry University, Harbin, Heilongjiang 150040, PR China
Lead triggers hepatocyte ferroptosis through coordinated mitochondrial injury and ER stress-mediated autophagic degradation of GPX4
作者Xi Qiu; Wenjie Yang; Xuejun Wang; Lei Zhang
作者单位College of Veterinary Medicine, Jilin Agricultural University, Changchun 130118, China; Engineering Research Center of Microecological Vaccines (Drugs) for Major Animal Diseases, Ministry of Education, Jilin Agricultural University, Changchun 130118, China; Division of Basic Biomedical Sciences, The University of South Dakota Sanford School of Medicine, Vermillion, SD, USA
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