医学
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The role of ER-α36 and RUNX2 interaction in breast cancer progression
作者Jia Sun; Xin Guan; Hongyan Li; Xiaoxia Shi; Xiaozhen Fu; Bingqiang Zhang; Mengmeng Chen; Chao Qu; Wei Zou
作者单位Liaoning Provincial Key Laboratory of Biotechnology and Drug Discovery, School of Life Science, Liaoning Normal University, Dalian, China; Stem Cell Clinical Research Center, National Joint Engineering Laboratory, Regenerative Medicine Center, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China; Qingdao Re-store Life Science Co., Ltd., Qingdao, Shandong, China
Synthesis and cytotoxicity studies of substituted ester-, amide- and urea-type ursane hybrids containing a 1,2,3-triazole linker
作者Sergey A. Popov; Elvira E. Shults; Mariya K. Marenina; Yulia V. Meshkova; Tatyana G. Tolstikova; Dmitry S. Baev; Andrey A. Nefyodov
作者单位Novosibirsk Institute of Organic Chemistry, Acad. Lavrentyev ave. 9, Novosibirsk 630090, Russia; Synchrotron Radiation Facility SKIF, G.K. Boreskov Institute of Catalysis SB RAS, Russian Federation SRF “SKlF”, 630559 Koltsovo, Russia; Novosibirsk State University, Pirogova St. 1, Novosibirsk 630090, Russian Federation
Adolescent chronic unpredictable mild stress impairs adult adrenal steroidogenesis in mice via glucocorticoid-mediated downregulation of SHH promoter H3K4me3 and hedgehog signaling
作者Yi Liu; Jing Ma; Ying Xiong
作者单位Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China; Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Β-Sitosterol-imidazolium ionic liquid conjugates: synthesis, computational evaluation, and anticancer activity against colorectal cancer cells
作者Suman Seervi; Saurabh Vyas; Nisarg Rana; Anu Manhas; Dhruvi Dipakbhai Patel; Juni Banerjee; Roli Mishra; Shuvomoy Banerjee
作者单位School of Biotechnology & Bioengineering, Institute of Advanced Research, Gyan Marg, Near GIFT City Bridge, Gandhinagar 382426, Gujarat, India; School of Humanities and Sciences, Institute of Advanced Research, Gyan Marg, Near GIFT City Bridge, Gandhinagar 382426, Gujarat, India; Department of Chemistry, School of Energy Technology, Pandit Deendayal Energy University, Gandhinagar 382426, Gujarat, India
MiR-144 regulates glucocorticoid sensitivity in acute respiratory distress syndrome via the GRβ/NF-κB axis
作者Shukun Hong; Yi Han; Hongye Wang; Xiaoguang Fan; Wenli Liu; Lujun Qiao; Lu Jiang; Jian Liu
作者单位Department of Intensive Care Unit, Shengli Oilfield Central Hospital, Dongying, China; Dongying Key Laboratory of Sepsis and Multiple Organ Injury, Dongying, China; Emergency Intensive Care Unit, Shengli Oilfield Central Hospital, Dongying, China; Department of Obstetrics and Gynecology, Shengli Oilfield Central Hospital, Dongying, China; Department of Rheumatology and Immunology, Shengli Oilfield Central Hospital, Dongying, China
Ten undescribed derivatives of lithocholic acid produced by biotransformation and their anti-neuroinflammatory activity
作者Chenhua Wang; Gang Chen; Wen Xu; Hossain M.D. Shohag; Alam Kazi M.D. Iftakhar; Huilian Huang; Guangtong Chen
作者单位Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, China; Department of Pharmacy, Dongtai People's Hospital, Yancheng 224200, China; School of Pharmacy, Nantong University, Nantong 226007, China
Metabolic, hormonal, and inflammatory profiling in lean and obese women with PCOS: A multicentre case–control study in a vegetarian population
作者Foram K. Ravat; Sneha M. Nair; Mayur Gandhi; Pallavi Ninama; Shital Punjabi; Dhaval Shah; Devang B. Sheth; Bhoomika Patel; Bhumika K. Maheriya; Kashyap N. Thummar
作者单位Department of Quality Assurance, Gujarat Technological University, School of Pharmacy, Gujarat Technological University, Gandhinagar, Gujarat, India; Obstetrics and Gynecology Department, GMERS Medical College & Civil Hospital, Sola, Ahmedabad, Gujarat, India; Obstetrics and Gynecology Department, Shashwat IVF Women's Hospital, Ahmedabad , Gujarat, India; Obstetrics and Gynecology Department, SAAVI Women's Hospital, Prahalad Nagar, Satellite, Ahmedabad 380015, Gujarat, India; Department of Pharmacology, L. M. College of Pharmacy, Ahmedabad, Gujarat, India; Department of Pharmacology, National Forensic Sciences University, Gandhinagar, India
Trifluoromethyl phenyl diazirine derivative of 20-methylamino-ANDROST-5-EN-3β-OL: Synthesis, docking, membrane permeability and bioconversion
作者Yaroslav V. Faletrov; Nina S. Frolova; Ludmila V. Isaeva; Ludmila A. Novikova; Michael A. Rubtsov; Nikolai N. Sluchanko
作者单位Research Institute for Physical Chemical Problems, Belarusian State University, Leningradskaya str, 14, Minsk, Belarus; Faculty of Chemistry, Belarusian State University, Leningradskaya Street, 14, Minsk, Belarus; Belozersky Institute of Physico-Chemical Biology, M.V. Lomonosov Moscow State University, Leninskie Gory, 1/40, 119234 Moscow, Russia; Faculty of Biology, M.V. Lomonosov Moscow State University, Leninskie Gory, 1/12, 119234, Moscow, Russia; Sechenov First Moscow State Medical University (Sechenov University), Moscow 119991, Russia; Lomonosov Moscow State University, Laboratoire Franco-Russe de Recherches en Oncologie, Moscow 119234, Russia; A.N. Bach Institute of Biochemistry, Federal Research Center of Biotechnology of the Russian Academy of Sciences, Leninsky Pr. 33, Moscow 119071, Russia; Faculty of Biology, Belarusian State University, Kurchatova Street, 10, Minsk, Belarus
DHCR24 inhibition upregulates desmosterol without promoting regression of atherosclerotic plaques in APOE*3-Leiden.CETP mice
作者Jing Miao; Lobke F. Zijlstra; Marieke Heijink; Iulia Sidorov; Jamie I. van der Vaart; Christoph Müller; Franz Bracher; Menno P.J. de Winther; Martin Giera; Annette E. Neele; Patrick C.N. Rensen; Sander Kooijman
作者单位Department of Medicine, Division of Endocrinology, and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, the Netherlands; Amsterdam UMC, location University of Amsterdam, Department of Medical Biochemistry, Amsterdam, the Netherlands; Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, the Netherlands; Amsterdam Institute for Immunology and Infectious disease, Amsterdam, the Netherlands; Department of Pharmacy, Center for Drug Research, Ludwig Maximilians University Munich, Munich, Germany
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