生物学
Paper Review Records
全部论文审稿周期
10 篇有效样本 · 按发表日期由新到旧排列
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Development of diversified HTS cell-based assays for solute carrier drug discovery
作者Francesca Sassone; Josefina Koch; Helena Batoulis; Sara Tremolada; Fernanda Ricci; Giovanna Maresca; Alexander Ehrmann; Lia Scarabottolo
作者单位Axxam SpA, 20091, Bresso, Milano, Italy; Bayer AG, Drug Discovery Sciences, Wuppertal, Germany
Forecasting a clear vision: How QSAR modeling catalyzes small molecule discovery in the field of corneal endothelial regeneration
作者Charissa Witters; Hans De Winter; Maxim Le Compte; Martin Ondra; Debbie Le Blon; Bert Van den Bogerd; Christophe Deben; Marián Hajdúch; Carina Koppen; Hendrik Vercammen
作者单位Antwerp Research Group for Ocular Science (ARGOS), Translational Neurosciences, Faculty of Medicine and Health Sciences, University of Antwerp, Universiteitsplein 1, Wilrijk, 2610, Belgium; Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium; DrugVision.AI, University of Antwerp, Wilrijk, Belgium; Laboratory of Medicinal Chemistry (UAMC), University of Antwerp, Wilrijk, Belgium; Center for Oncological Research (CORE), University of Antwerp, Wilrijk, Belgium; Laboratory of Experimental Medicine, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic
Application of dual-view oblique plane microscopy to small-molecule compound screening across 3D glioblastoma stem cell spheroids with single-cell resolution
作者Martin Lee; Jayne Culley; Hugh Sparks; Yuriy Alexandrov; Nils Gustafsson; Alexander E.P. Loftus; Chris Dunsby; Neil O Carragher
作者单位Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK; Light Community, Department of Physics, Imperial College London, London, SW7 2AZ, UK; Photonics Satellite Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK
AI-driven identification of Zika virus inhibitors
作者Yuka Otsuka; Justin Shumate; Teresa Findley Rye; Ilya Goldberg; Amanda Clement; Louis Scampavia; Donghoon Chung; Timothy P. Spicer
作者单位Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Department of Molecular Medicine, Jupiter, FL 33458, USA; ViQi, Inc, 315 Meigs Road, Suite A261, Santa Barbara, CA, 93109, USA; Araceli Biosciences, 7405 SW Tech Center Dr, Suite A160, Tigard, OR, 97223, USA; Center for Predictive Medicine, Department of Microbiology Immunology, School of Medicine, University of Louisville, Louisville, KY 40202, USA
A high throughput screening platform for label-free identification and characterization of GPCR ligands using impedance-based real-time cellular analysis
作者Frederik Bangnowski; Robert Ries; Michael Karnath; Amaury Fernández-Montalván; Esther Schmidt
作者单位Department of Drug Discovery Sciences, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, 88397, Germany; Department of Cardio-Renal-Metabolic Disease Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, 88397, Germany
Three high throughput compatible cell-based assays for identifying small molecule JAG1 upregulators for Alagille syndrome
作者Molly R Kulikauskas; Xiuli Huang; Ivan Pavlinov; Phillip Sanchez; Guibin Chen; Dvir Blivis; Ty Voss; Karsten Baumgaertel; Steve Rodems; Atena Farkhondeh; Wei Zheng; Catherine Z Chen
作者单位National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA; Alagille Syndrome Alliance (ALGSA), Collierville, TN, USA; Travere Therapeutics, San Diego, CA, USA
From complexity to clarity: Building dashboards for hit selection in high throughput screens
作者Karla J Cowley; Hermione Allen; Kaylene J Simpson
作者单位Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia
A Hybrid Experimental and in silico Platform for ITPK1 Chemical Probe Discovery
作者Adam Yasgar; Sankalp Jain; Huanchen Wang; Chih-Shia Lee; Guangning Zong; Haibo Zhang; Eric Lindberg; Carolyn Woodroofe; Kelly Lane; Burchelle Blackman; Dan Crooks; Hsiuling Lin; Bolormaa Baljinnyam; Michael Ronzetti; Anton Simeonov; Sandeep Rana; Ganesha Rai; Stephen Shears; Robin E. Stanley; Alexey V. Zakharov; Ji Luo; Natalia J. Martinez
作者单位National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA; Molecular and Cellular Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health Bethesda, MD, 20892, USA; Chemistry and Synthesis Center, National Heart, Lung and Blood Institute, Bethesda, MD, 20814, USA
CellVision: A deep learning based image analysis platform to accelerate immuno-plaque assay data processing for dengue vaccine development
作者Yi Wang; Michelle N. Ngo; Shubing Wang; Justin Jarrah; Hossein Salami; Carl Hofmann; Anjali Joshi; Daniel Skomski; John W. Loughney
作者单位Analytical Research & Development, MRL, Merck & Co., Inc., Rahway, NJ, USA; Biostatistics and Research Decision Sciences, MRL, Merck & Co., Inc., Rahway, NJ, USA; Digital Services, MMD, Merck & Co., Inc., Rahway, NJ, USA
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