医学
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11 篇有效样本 · 按发表日期由新到旧排列
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Triarylphosphonium-conjugated Sn( iv )-porphyrins for antimicrobial photodynamic therapy: impact of substituents on lipophilicity, aggregation, and photoantibacterial activity
作者Gayathri MP; Nandhakumar Muruganandam; Sutharsan Govindarajan; Balaji Babu
作者单位1. Department of Chemistry, SRM University-AP, India; 2. Department of Biological Sciences, SRM University-AP, India
The effects of bioisostere substitution on the antimicrobial and physicochemical properties of supramolecular self-associating amphiphiles
作者Pinky K. Naicker; Mariam Yacoub; Lisa J. White; Dominick E. Balderston; Perry A. Hailey; J. Mark Sutton; Charlotte K. Hind; Jennifer R. Hiscock
作者单位1. University of Kent, Canterbury, CT2 7NH, UK; 2. Countermeasures Development and Evaluation Preparedness, UKHSA, Salisbury SP4 0JG, UK
Discovery of dihydrospiro[cyclopropane-1,7′-pyrrolo[3,4- d ]pyrimidine] derivatives as novel ATR inhibitors
作者Xiaozhen Chen; Yunbo Qian; Yitong Guo; Junfei Li; Lei Xu; Xingxing Zeng; Kailong Jiang; Yubo Zhou; Jia Li; Tao Liu
作者单位1. Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, Zijingang Campus, Hangzhou 310058, P. R. China; 2. Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan 528400, China; 3. State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China
Design, synthesis and exploration of cyclic imides as PDE4 inhibitors in psoriasis
作者Veena K. S.; Pallabi Panja; Tirtha Nath; V. G. M. Naidu; Kalyan K. Sethi
作者单位1. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Guwahati 781101, Assam, India; 2. Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Guwahati 781101, Assam, India
Harnessing carlina oxide scaffold for the management of vector-borne diseases: synthesis and structure–activity relationship
作者Eleonora Spinozzi; Alessia Piergentili; Marta Ferrati; Cecilia Baldassarri; Giada Trebaiocchi; Paolo Rossi; Fabrizio Araniti; Alice Zambelli; Loredana Cappellacci; Laura Zeppa; Martina Giangrossi; Alessandro Palmieri; Roman Pavela; Filippo Maggi; Riccardo Petrelli
作者单位1. Chemistry Interdisciplinary Project (ChIP) research center, School of Pharmacy, University of Camerino, Via Madonna delle Carceri, 62032 Camerino, Italy; 2. School of Biosciences and Veterinary Medicine, University of Camerino, Via Gentile III Da Varano, 62032, Camerino, Italy; 3. Department of Agricultural and Environmental Sciences, Production, Landscape, Agroenergy, University of Milan, Via Celoria 2, 20133 Milan, Italy; 4. School of Biosciences and Veterinary Medicine, Immunopathology and Molecular Medicine Unit, University of Camerino, Via Madonna delle Carceri 9, 62032 Camerino, Italy; 5. School of Pharmacy, University of Camerino, Via Madonna delle Carceri 9/C, 62032Camerino, Italy; 6. School of Science and Technology, Chemistry Division, University of Camerino, 62032 Camerino, Italy; 7. Czech Agrifood Research Center, Dunovská 507, 16106 Prague 6, Ruzyně, Czech Republic; 8. Department of Plant Protection, Czech University of Life Sciences Prague, Kamycká 129, 16500 Prague 6, Suchdol, Czech Republic; 9. Department of Plant Biotechnology, College of Life Sciences and Biotechnology, Korea University, 02841 Seoul, Republic of Korea
Integrated computational screen and validation of thalidomide-based PROTACs targeting SARS-CoV-2 main protease
作者Li-Na Guo; Yu-Hua Li; Rou-Yu Zhu; Ni Su; Zhi-Yu Shao; Hua Diao
作者单位1. NHC Key Lab of Reproduction Regulation, Shanghai Engineering Research Center of Reproductive Health Drug and Devices, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai 200237, China; 2. College of Chemistry and Chemical Engineering, Donghua University, Shanghai 201620, China
An overview of recent advancements in targeted cancer therapies and their potential clinical impact
作者Shujauddin Ahmed; Akash P. Sakla; Kousar Jahan; Naziya Neshat; Mymoona Akhter; Shams Aaghaz; Ahmed Kamal
作者单位1. Department of Pharmaceutical Chemistry, GITAM School of Pharmacy, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, 530045, India; 2. Department of Pharmaceutical Chemistry, Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Parul University, Vadodara, Gujarat, 391760, India; 3. Lloyd Institute of Management and Technology (Pharm), Plot no. 11, Knowledge Park-II, Greater Noida 201306, UP, India; 4. School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi, 110062, India; 5. Department of Chemistry and Biochemistry, Baylor University, One Bear Place, Waco, Texas 76706, USA; 6. Birla Institute of Technology & Science (BITS), Pilani Hyderabad Campus, Hyderabad, Telangana, 500078, India; 7. Deparment of Chemistry, Osmania University, Hyderabad, 500007, India
Synthesis and evaluation of enantiomeric quinoline-2-carboxamides: positron emission tomography imaging agents for the translocator protein
作者Lachlan J. N. Waddell; Mark G. MacAskill; Holly McErlain; Timaeus E. F. Morgan; Lewis Williams; Victoria J. M. Reid; Anna Beyger; Sally L. Pimlott; Adriana A. S. Tavares; Andrew Sutherland
作者单位1. School of Chemistry, University of Glasgow, University Avenue, Glasgow, G12 8QQ, UK; 2. Edinburgh Imaging, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK; 3. University/BHF Centre for Cardiovascular Sciences, University of Edinburgh, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK; 4. West of Scotland PET Centre, Greater Glasgow and Clyde NHS Trust, Glasgow, G12 OYN, UK
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