医学
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Efficacy and safety of magnesium glycinate as add on therapy in hypomagnesemic asthma and chronic obstructive pulmonary disease patients: A randomised controlled study assessing inflammatory biomarkers
作者Maneesh Kumar Maddirevula; Muhasaparur G. Rajanandh; Boman Wesley
作者单位Department of Pharmacy Practice, SRM College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Kattankulathur, Chengalapattu, Tamil Nadu, 603203, India; Department of Pharmacy Practice, Mahathi College of Pharmacy, Madanapalle, Andhra Pradesh, 517319, India; Department of Pulmonary Medicine, Arogyavarm Medical Center, Madanapalle, Andhra Pradesh, 517319, India
m6A reader IGF2BP2 mediates airway remodeling by stabilizing Dixdc1 in asthma pathogenesis
作者Xiao-Mang Li; Bi-Wen Mo; Yan Gao; Yun-Xiang Chen; Bo Xiao; Yue Gu; Miao-Miao Liang; Hui-Min Li
作者单位Guilin Medical University, Guilin, 541004, Guangxi, China; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guilin Medical University, Guilin, 541001, Guangxi, China; Respiratory Disease Laboratory, The First Affiliated Hospital of Guilin Medical University, Guilin, 541004, Guangxi, China
Real-life application of the optical beta-adrenergic sweat test for people with cystic fibrosis
作者Karina Kleinfelder; Anca Manuela Hristodor; Giorgio Centin; Antonella Casiraghi; Paola Minghetti; Emily Pintani; Marina Bertini; Claudio Sorio; Paola Melotti
作者单位Department of Medicine, Division of General Pathology, Cystic Fibrosis Laboratory “D. Lissandrini”, University of Verona, Verona, 37134, Italy; Cystic Fibrosis Centre, Azienda Ospedaliera Universitaria Integrata Verona, Verona, 37126, Italy; Department of Pharmaceutical Sciences, Università degli Studi di Milano, via G. Colombo 71, Milan, 20133, Italy
Effects of anumigilimab, an anti–G-CSF receptor mAb, after segmental LPS challenge: A Phase 1b trial in healthy volunteers
作者Jens M. Hohlfeld; Meike Müller; Philipp Badorrek; Laurent B. Nicolas; Oliver Vit; William G. Darby; Judith Field; Michael Larbig
作者单位Division of Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Nikolai-Fuchs-Str. 1, Hannover, 30625, Germany; Department of Respiratory Medicine and Infectious Disease, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover, 30625, Germany; Member of the German Center for Lung Research (DZL), BREATH, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover, 30625, Germany; Clinical Pharmacology and Pharmacometrics, CSL Behring AG, Wankdorfstrasse 10, Bern, 3014, Switzerland; Clinical Development, CSL Behring AG, Wankdorfstrasse 10, Bern, 3014, Switzerland; CSL Innovation, 30 Flemington, Parkville, 3010, Australia
PD05, a novel neutrophil elastase inhibitor, mitigates LPS-induced acute lung injury in a preclinical model
作者Sabita Singh; Ashish Jaiswal; Joytri Dutta; Archita Ray; Sayantan Sengupta; Sudip Dey; Arun Bandyopadhyay; Parasuraman Jaisankar; Ulaganathan Mabalirajan
作者单位Molecular Pathobiology of Respiratory Diseases, Cell Biology and Physiology Division, Council of Scientific and Industrial Research (CSIR)-Indian Institute of Chemical Biology (IICB), Kolkata, West Bengal, 700091, India; Cardiovascular Disease & Respiratory Disorders Laboratory, Department of Cell Biology & Physiology, CSIR-Indian Institute of Chemical Biology, Kolkata, India; Organic and Medicinal Chemistry Division, Council of Scientific and Industrial Research (CSIR)-Indian Institute of Chemical Biology (IICB), Kolkata, West Bengal, 700091, India; Gujarat Biotechnology University, India
Synergistic induction of apoptosis in lung cancer cells via TOP2A targeting through combined dihydroartemisinin and chrysin treatment
作者Haidi Sun; Li Han; Hongwei Wu; Hongsheng Xue; Ming-Fei Lang; Jingyu Tan
作者单位The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, 121012, China; Medical College, Dalian University, Dalian, Liaoning, 116622, China; Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, 116001, China; School of Software Engineering, Dalian University, Dalian, Liaoning, 116622, China
Evodiamine protects against lung ischemia–reperfusion injury by attenuating SYK-associated TLR4/NLRP3 inflammasome activation and ferroptosis-related injury signatures
作者Wei Peng; Baiping Ge; Rui Zhang; Yunen Liu; Changci Tong; Chenguang Dong
作者单位Department of Pulmonary and Critical Care Medicine, The People's Hospital of Liaoning Province, Liaoning, 110016, China; Department of Emergency, The People's Hospital of Liaoning Province, Liaoning, 110016, China; Department of Pulmonary and Critical Care Medicine, Liaoning Fangda General Hospital, Liaoning, 110172, China; Shenyang Medical College, No. 146, Huanghe North Street, Shenyang, Liaoning, 110034, China
Evaluation of the effect of modulator therapies on medication complexity in adult cystic fibrosis patients
作者Esen Deniz Akman Ar; Nadir Yalçın; Uğur Balaban; Oğuz Karcıoğlu; Ebru Damadoğlu; Ali Fuat Kalyoncu; Kutay Demirkan
作者单位Department of Clinical Pharmacy, Faculty of Pharmacy, Hacettepe University, Ankara, Türkiye; Department of Pulmonary Medicine, Faculty of Medicine, Hacettepe University, Ankara, Türkiye
Nicotinamide N-oxide alleviates sepsis-induced acute lung injury by inhibiting ferroptosis through activation of the SIRT1/AKT signalling pathway
作者Shujuan Liu; Mian Fu; Xiguang Liu; Yichen Jin; Liwen Fan; Qingyan Ni; Zihan Xu; Yusa Li; Jiawen Zhou; Huizhen Chen
作者单位Institute of Neuroscience, Department of Neurosurgery, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang Clinical College of Nanjing Medical University, The First People's Hospital of Lianyungang, Lianyungang, 22000, China; Jiangsu Marine Pharmaceutical Resources Development Engineering Research Center, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, College of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China
Pulmonary safety of Staccato alprazolam in healthy participants and participants with mild asthma: Phase 1, randomized, double-blind, placebo-controlled trial
作者S. David Miller; Craig F. LaForce; Laura Barlow; Shikiko Watanabe; Aliceson King; Maria Burian; Hugues Chanteux
作者单位Northeast Medical Research Associates, North Dartmouth, MA, USA; North Carolina Clinical Research, Raleigh, NC, USA; Veramed, Twickenham, UK; UCB, Braine-l'Alleud, Belgium; UCB, Smyrna, GA, USA
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