生物学
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A tethered yeast surface display system facilitates enriching epitope-specific binding interactions
作者Rojhae A Panton; Jakob Lind; Amanda Richardson; Isabela Panozzo; Daniela Gomez Garcia; Syed Muzaffar; Lawrence A Stern
作者单位1. Department of Chemical, Biological, and Materials Engineering, University of South Florida , Tampa, FL 33620 ,; 2. Department of Medical Engineering, University of South Florida , Tampa, FL 33620 ,
Prioritizing stability-enhancing mutations using the ESM protein language model in conjunction with physics-based MM/GBSA predictions
作者Emily R Rhodes; Guido Scarabelli; Jonathan Jou; Jacob Byerly; Kayla G Sprenger; Eliud O Oloo
作者单位1. Department of Chemical and Biological Engineering, University of Colorado Boulder , Jennie Smoly Caruthers Biotechnology Building, 3415 Colorado Ave, Boulder, CO 80303 ,; 2. Schrödinger Inc , 9868 Scranton Rd Suite 3200, San Diego, CA 9212 ,; 3. Schrödinger Inc , 1540 Broadway Floor 24, New York, NY 10036 ,; 4. Biomedical Engineering Program, University of Colorado Boulder , 1111 Engineering Drive, Boulder, CO 80309 ,; 5. Schrödinger Inc , 1 Main St 11th Floor, Cambridge, MA 02142 ,
Mapping functional dynamics hotspots for protein engineering with NMR peak intensity analysis
作者Adam M Damry; Serena E Hunt; Sandrine Legault; Michael C Thompson; Natalie K Goto; Roberto A Chica
作者单位1. Department of Chemistry and Biomolecular Sciences, University of Ottawa , 10 Marie-Curie, Ottawa, ON K1N 6N5 ,; 2. Department of Chemistry and Biochemistry, University of California, Merced , Merced, CA 95343 ,
Free energy–guided Q302P mutation in GH1 β -glucosidase from Aspergillus fumigatus improves enzyme function via catalytic tunnel perturbation
作者Shalini Das; Subba Reddy Dodda; Musaddique Hossain; Soumyadeep Ray; Sudit S Mukhopadhyay
作者单位1. Department of Biotechnology, National Institute of Technology, Durgapur , West Bengal 713209 ,; 2. Research scientist, Advanced Enzymes , Thane, Maharashtra 400604 ,; 3. Department of Computational Biology, Indraprastha Institute of Information Technology, Delhi , Okhla Phase III, New Delhi 110020 ,
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