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Development and validation of dynamic clinical subphenotypes for acute pancreatitis using hematocrit and blood urea nitrogen trajectories in intensive care unit: a multicenter retrospective cohort study
作者Jianhua Wan; Maobin Kuang; Shixuan Xiong; Yaoyu Zou; Huajing Ke; Wenhua He; Yin Zhu; Nonghua Lu; Liang Xia
作者单位Department of Gastroenterology, Jiangxi Provincial Key Laboratory of Digestive Diseases, Jiangxi Clinical Research Center for Gastroenterology, Digestive Disease Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China
Nrf2 deficiency in myeloid cells accelerates atherosclerosis by promoting the inflammatory response and impairing efferocytosis
作者Xiaoge Xu; Cuijie Liu; Jinshan Bo; Hongbin Wang; Yusen Zhang; Yuanyuan Xu; Jingqi Fu; Jingbo Pi; Huihui Wang
作者单位Key Laboratory of Environmental Stress and Chronic Disease Control & Prevention Ministry of Education (China Medical University), No. 77 Puhe Road, Shenyang, Liaoning 110122, PR China; Key Laboratory of Liaoning Province on Toxic and Biological Effects of Arsenic (China Medical University), No. 77 Puhe Road, Shenyang, Liaoning 110122, PR China; School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang, Liaoning 110122, PR China
Whole-genome sequencing identifies genetic diversity and adaptive signatures of hypoxia and ultraviolet radiation in Chinese chickens
作者Semiu Folaniyi Bello; Endashaw Terefe; Haoqiang Ye; Adeniyi Charles Adeola; Zhen Zhou; Endashaw Jebessa; Lin Qi; Ridwan Olawale Ahmed; Kelvin Dodzi Aloryi; Obiajulu Emenike Ositanwosu; Sunday James Eludodun; Zhaofeng Zhang; Bashir Bolaji Tiamiyu; Afusat Kikelomo Ladejobi; Abulgasim M. Ahbara; Bashir Salim; Dylan O’Neill Rothenberg; Oludoyin Adeseun Adigun; Xiquan Zhang; Bolin Cai; Olivier Hanotte; Qinghua Nie
作者单位State Key Laboratory of Livestock and Poultry Breeding, Guangdong Laboratory for Lingnan Modern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affairs, National-Local Joint Engineering Research Center for Livestock Breeding, Guangzhou, China; Agriculture Research Group, Organization of African Academic Doctors (OAAD), Off Kamiti Road, P. O. Box 25305-00100, Nairobi, Kenya; Arsi University, College of Agriculture and Environmental Science, Department of Animal Science, Asella, Ethiopia; State Key Laboratory of Genetic Evolution & Animal Models and Yunnan Key Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China; State Key Laboratory of Swine and Poultry Breeding Industry, Guangdong Key Laboratory of Animal Breeding and Nutrition, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China; Department of Animal and Avian Sciences, University of Maryland, College Park, MD 20742, United States; Department of Horticultural Sciences, University of Florida, Gainesville, FL, United States; Department of Computer Science, Nnamdi Azikiwe University, P.M.B. 5025, Awka, Nigeria; Department of Animal Science, Faculty of Agriculture, University of Ibadan, Ibadan, Nigeria; Department of Plant Biology, Faculty of Life Sciences, University of Ilorin, Ilorin, Nigeria; Department of Plant Science and Landscape Architecture, University of Connecticut, United States; Animal Biotechnology Unit, Department of Animal Breeding and Genetics, Federal University of Agriculture, Abeokuta, P.M.B 2240, Nigeria; Animal and Veterinary Sciences, SRUC, The Roslin Institute Building, Midlothian, Edinburgh, United Kingdom; Department of Zoology, Faculty of Sciences, Misurata University, Misurata, Libya; Camel Research Center, King Faisal University, P.O. Box 400, Al-Ahsa 31982, Saudi Arabia; College of Horticulture, South China Agricultural University, Guangzhou 510642 Guangdong, China; Department of Biology, University of Waterloo, Waterloo ON N2L 3G1, Canada; School of Science and the Environment/Boreal Ecosystems and Agricultural Sciences, Grenfell Campus, Memorial University of Newfoundland, Corner Brook, NL A2H 5G4, Canada; LiveGene-Centre for Tropical Livestock Genetics and Health (CTLGH), International Livestock Research Institute (ILRI), Addis Ababa, Ethiopia; School of Life Sciences, University of Nottingham, University Park, Nottingham, United Kingdom
Multi-omics reveals an ecdysone-activated Eip75B-FABP signaling axis coordinating nutrient metabolism for development in Hermetia illucens
作者Mengyao Dong; Zhenyu Zhang; Zhe Li; Tingting Yan; Ahmed R. Henawy; Ying Meng; Yiwen Li; Meiqi Li; Feng Huang; Minmin Cai; Jibin Zhang; Ziniu Yu; Jun Li; Qiyun Xu; Longyu Zheng
作者单位National Key Laboratory of Agricultural Microbiology, Frontiers Science Center for Animal Breeding and Sustainable Production, National Engineering Research Center of Microbial Pesticides, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430000, China; Hubei Hongshan Laboratory, Wuhan 430000, China; National Key Laboratory of Agricultural Microbiology, Key Laboratory of Horticultural Plant Biology (MOE), College of Plant Science and Technology, Institute of Urban and Horticultural Entomology, Huazhong Agricultural University, Wuhan 430000, China; Department of Microbiology, Faculty of Agriculture, Cairo University, 12613 Giza, Egypt; Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Institute of Zoology, Guangdong Academy of Sciences, Guangzhou 510260, China
A chitosan-based aerogel with radially aligned structure for cushioning and antimicrobial packaging of fruits
作者Liwen Liang; Xinru Liu; Yiyi Li; Xiaochun Bian; Yongqiang Wen; Zhu Zhu
作者单位School of Chemistry and Bioengineering, University of Science & Technology Beijing, Beijing 100083, China
Essential function of Nr4a2 in subicular development and social novelty
作者Xi-Yue Liu; Yun-Chao Tao; Qiong Zhang; Wei-Tang Liu; Li Zhao; Zhi-Bin Hu; Bing-Yao Zhou; Ze-Xuan Li; Cong-Cong Qi; Lei Zhang; Jia-Yin Chen; Ning-Ning Song; Yu-Qiang Ding
作者单位State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai 200032, China; Laboratory Animal Center and MOE Mouse Resource Center, Fudan University, Shanghai 200032, China; Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China; Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai 200092, China; Clinical Center for Brain and Spinal Cord Research, Tongji University, Shanghai 200092, China; Huashan Institute of Medicine (HS-IOM), Huashan Hospital, Fudan University, Shanghai 200040, China
Combinatorial genome engineering of pseudorabies virus Bartha by developing a reverse genetic system based on three overlapping genomic segments
作者Hengxing Yuan; Yulu Zhang; Long Tan; Yue Yang; Ji Luan; Hailong Wang
作者单位State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Helmholtz International Lab for Anti-infectives, Shandong University–Helmholtz Institute of Biotechnology, Shandong University, Qingdao, Shandong 266237, China; Rizhao Research Institute of Shandong University, Rizhao, Shandong, China
Noninvasive detection and differentiation of gastric malignancy using cell-free DNA biomarkers
作者Hengzhen Li; Meng Chen; Ying Liu; Haimeng Tang; Guangtao Jiao; Ling Qu; Yushuai Song; Dan Jiang; Chuanfeng Mo; Xiaona Fan; Yisheng Dai; Zhuo Chen; Haitao Wang; Ruowei Yang; Dongqin Zhu; Xiuxiu Xu; Hua Bao; Henan Zhou; Huaxing Wu; Wenhui Li; Huike Yang; Chao Liu; Zhiwei Li
作者单位Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Department of Gastroenterology, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Henan 450008, China; Department of Anatomy, School of Basic Medical Sciences, Harbin Medical University, Harbin, China; Department of Clinical Laboratory, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang 150081, China; Department of Endoscope, Harbin Medical University Cancer Hospital, Harbin 150081 Heilongjiang Province, China; Geneseeq Research Institute, Nanjing Geneseeq Technology Inc., Nanjing, Jiangsu 210032 China
Unique molecular architecture of N-glycosylated TM4SF5 dimer highlights evolutionary and structural divergence among small four-transmembrane protein families
作者Yoonji Lee; Ji Eon Kim; Wonsik Kim; Soyeon Kim; Ri Han; Donghyuk Suh; Eunmi Kim; Eun-Ae Shin; Kyung-hee Pyo; Jae-Ho Lee; Sanghee Yoon; Yong-In Kim; Je-Yoel Cho; Sun Choi; Jung Weon Lee
作者单位College of Pharmacy, Chung-Ang University, Seoul 06974, the Republic of Korea; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, the Republic of Korea; Department of Integrative Bioscience & Biotechnology, Sejong University, Seoul 05006, the Republic of Korea; Global AI Drug Discovery Center, College of Pharmacy and Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, the Republic of Korea; Department of Biochemistry, College of Veterinary Medicine, Seoul National University, Seoul 08826, the Republic of Korea
Identification of marginal zone B cells in head and neck cancer with immunomodulatory characteristics
作者Jiantong Bao; Jochen Hess; Annika C. Betzler; Zhen Zhang; Miltiadis Tsesmelis; Sebastian Schmid; Gaurav Berry; Patrick J. Schuler; Jens Greve; Simon Laban; Thomas K. Hoffmann; Medhanie Mulaw; Cornelia Brunner
作者单位Department of Otorhinolaryngology and Head & Neck Surgery, University Medical Center Ulm, Head & Neck Cancer Center of the Comprehensive Cancer Center Ulm, Ulm, Germany; School of Medicine, Southeast University, Nanjing, China; Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg University Hospital, Heidelberg, Germany; Unit for Single-Cell Genomics, Medical Faculty, Ulm University, Ulm, Germany; Department of Anesthesiology and Intensive Care Medicine, Ulm University Medical Center, Ulm, Germany; Core Facility Immune Monitoring, Medical Faculty, Ulm University, Ulm, Germany
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