医学
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审稿天数=录用日期-收稿日期;保留 PDF/DOI/网页源链接
PBPK model of carbamazepine and its metabolite for bioequivalence assessment: prioritizing early exposure and single-dose study designs
作者Javier Zarzoso-Foj; Marina Cuquerella-Gilabert; Javier Reig-López; Víctor Mangas-Sanjuán; Alfredo García-Arieta
作者单位Department of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia 46010 Valencia, Spain; Interuniversity Research Institute for Molecular Recognition and Technological Development, Polytechnic University of Valencia, University of Valencia 46100 Valencia, Spain; Division of Pharmacology and Clinical Evaluation, Department of Human Use Medicines, Spanish Agency for Medicines and Health Care Products, 28022 Madrid, Spain
Development and evaluation of a virus-like particle PEDV vaccine based on MS2 bacteriophage
作者Yawen Liu; Siying Du; Shan Xu; Yigang Tong
作者单位BAICSM, State Key Laboratory of Green Biomanufacturing, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China
A carrier-free self-assembled mangiferin hydrogel as a dual-functional oral delivery system for baicalin against acetaminophen-induced acute liver injury
作者Xinyu Huang; Shouyu Zhu; Kun Feng; Xianggen Wu; Han Wang; Dexiang Xu
作者单位College of Chemical Engineering, Qingdao University of Science and Technology, 266042 Qingdao, PR China; School of Medicine, University of Health and Rehabilitation Sciences, Qingdao, PR China; Women and Children’s Hospital, Qingdao University, Qingdao 266034, PR China
Improved oral bioavailability of dihydromyricetin using β-cyclodextrin-grafted chitosan/tocopheryl polyethylene glycol succinate nano-delivery system: preparation, characterization, in-vitro evaluation and pharmacokinetics
作者Yijin Deng; Rang Yang; Wenyou Ding; Jinqing Chen; Huijuan Wei; Haoxiang Fan; Yi Wang; Xian Luo; Lina Lan; Hailan Qin; Minjie Jiang; Wenya Ding
作者单位Key Laboratory of Common Technology of Traditional Chinese Medicine Preparation, Guangxi University of Chinese Medicine, Nanning 530200, Guangxi, China; Guangxi Engineering Research Center of Characteristic Traditional Chinese Medicine and Ethnomedicine, Guangxi University of Chinese Medicine, Nanning 530200, Guangxi, China; Guangxi Engineering Technology Research Center of Advantage Chinese Patent Drug and Ethnic Drug Development, Guangxi University of Chinese Medicine, Nanning 530200, Guangxi, China; Harbin Medical University, Harbin 150081, Heilongjiang, China; College of Basic Courses, Wuhan Donghu University, Wuhan 430000, Hubei, China; Guangxi Engineering Research Center for Graphene Biomedical Application Technology,Guangxi University of Chinese Medicine, Nanning 530000, Guangxi, China
Targeted topical delivery of Ruxolitinib-Loaded nanoemulgel for potential management of Atopic Dermatitis: An integrated in silico, in vitro, and in vivo approach
作者Ganesh Vambhurkar; Anamika Sharma; Rahul Kumar; Paras Famta; Vivek Phatale; Abhishek Sharma; Etikala Amulya; Saurabh Srivastava
作者单位Pharmaceutical Innovation and Translational Research Lab (PITRL), Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India; Department of Biological Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, India
Solubility-Enhanced dragon’s blood in a PEI/PAA xerogel powder for accelerated chronic wound healing
作者Hao Wang; Shuang Wang; Guohua Wang; Dawei Chen; Ming Zhao; Haiyang Hu
作者单位Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenyang 110016, PR China; Fangyuan-pharma, No. 1018, LiaoHe Road, Xinbei District, Changzhou, Jiangsu, PR China
Towards macrophage-oriented Antituberculosis therapy: nanohydrogel and liposomal delivery of rifampicin–berberine Co-nanocrystals for enhanced intracellular Antituberculosis activity
作者Xiaoguo Zhang; Ping Liu; Shengwei Ji; Jingxue Liu; Shouhua Cui; Xue Hu; Zhengbin Chai; Ibrahim Oluwatobi Kehinde; Nontobeko E. Mvubu; Mahmoud E.S. Soliman; Zhongfa Zhang
作者单位Department of Infectious Diseases, Public Health Clinical Center Affiliated to Shandong University, Jinan 250013, China; Public Health Clinical Center Affiliated to Shandong University, Jinan 250013, China; Department of Clinical Laboratory, Public Health Clinical Center Affiliated to Shandong University, Jinan 250013, China; Molecular Bio-computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4001, South Africa; Discipline of Medical Microbiology, School of Laboratory Medicine and Medical Science, Nelson Mandela Medical School, University of KwaZulu-Natal (UKZN), South Africa; Department of Medical Biosciences, Faculty of Natural Sciences, University of the Western Cape, Cape Town, South Africa; Department of Respiratory Medicine, Public Health Clinical Center Affiliated to Shandong University, Jinan 250013, China
A hybrid MVDA-neural network model with auxiliary learning for pharmaceutical quality by design under small-sample constraints
作者Dongjun Lee; Heejae Kim; Yongjae Park; Seung Eel Oh; Eun-Ji Heo; Sujin Lee; Chang-Jae Chun; Dong-Jin Jang; Taeyong Sim
作者单位Department of Artificial Intelligence and Data Science, Sejong University, Seoul 05006, the Republic of Korea; Food Safety and Distribution Research Group, Korea Food Research Institute, Wanju 55365, the Republic of Korea; Department of Bio-Health Technology, College of Biomedical Science, Kangwon National University, Chuncheon 24341, the Republic of Korea; Department of Pharmacy, College of Pharmacy, Kangwon National University, Chuncheon 24341, the Republic of Korea
Design and development of inhalable cefepime dry powder targeting P. aeruginosa infections
作者Prodip Kumar Baral; Shubhra Sinha; Daniel Pletzer; Shyamal C. Das
作者单位School of Pharmacy and Pharmacology, Faculty of Health Professional Programmes, University of Otago, Dunedin, New Zealand; Department of Microbiology and Immunology, Faculty of Biomedical Sciences, University of Otago, New Zealand; Department of Pharmacy, Faculty of Biological Sciences, Noakhali Science and Technology University, Noakhali, Bangladesh; Department of Physiology, Faculty of Biomedical Sciences, University of Otago, New Zealand
18β-glycyrrhetinic acid as a promising co-former for co-amorphous systems fabrication
作者Jia Deng; Yangwen Peng; Xiaoju Shi; Jialu Hu; Qian Dai; Ningbo Pang; Zhe Wang; Xin Chen; Hailu Zhang
作者单位Clinical Laboratory, Institute of Rheumatology and Immunology, Affiliated Hospital of North Sichuan Medical College & Innovation Centre for Science and Technology, North Sichuan Medical College, Nanchong, Sichuan 637000, PR China; Suzhou Vocational Health College, Suzhou 215009, PR China; Interdisciplinary Institute of NMR and Molecular Sciences, Key Laboratory of Hubei Province for Coal Conversion and New Carbon Materials, School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan 430081, PR China; Hunan Provincial Key Laboratory of Basic and Clinical Pharmacological Research of Gastrointestinal Cancer, Department of Pharmacy, Institute of Pharmacy and Pharmacology, the Second Affiliated Hospital, University of South China, Hengyang, Hunan 421001, PR China
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