医学
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Targeting the AMPK/SIRT1-NLRP3 inflammasome axis: Simvastatin, Ezetimibe, and their combination attenuate 3-nitropropionic acid-induced striatal neurodegeneration in rats
作者Abobakr M. Rezqallah; Eman M. Raafat; Shahira Nofal
作者单位Pharmacology and Toxicology Department, Faculty of Pharmacy, Capital University (Formerly Helwan University), Ein Helwan, Egypt
Neuroprotective effects of chitosan nanoparticle-loaded orientin in a 6-OHDA-induced Parkinson's disease experimental model in rats
作者Volkan Gelen; Cemil Bayram; Adem Kara; Deniz Tekiner; Ali Yeşildağ
作者单位Department of Physiology, Faculty of Veterinary Medicine, Kafkas University, Kars, Turkey; Department of Pharmacology, Faculty of Veterinary Medicine, Atatürk University, Erzurum, Turkey; Department of Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkey; Department of Histology and Embryology, Faculty of Veterinary Medicine, Atatürk University, Erzurum, Turkey; Department of Bioengineering, Faculty of Engineering and Architecture, Kafkas University, Kars, Turkey
α7 nicotinic acetylcholine receptor activation promotes anxiety- and depressive-like behaviors associated with CREB/CRH signaling in the hypothalamic paraventricular nucleus
作者Canmao Wang; Rongtian Li; Yufan Wu; Zixi Hong; Shijie Huang; Yindan Ye; Waijiao Tang; Xixiao Yang; Danna Gan
作者单位Department of Pharmacy, Shenzhen Hospital, Southern Medical University, Shenzhen, 518100, China; Department of Pharmacy, Southern University of Science and Technology Hospital, Southern University of Science and Technology, Shenzhen, 518055, China; Integrative Microecology Clinical Center, Department of Gastroenterology, Shenzhen Clinical Research Center for Digestive Disease, Shenzhen Hospital, Southern Medical University, Shenzhen, 518100, China
Cocaine-induced interindividual variability in female rats: From behavior to gene expression
作者Joséphine Gasparri; Emmanuel Curis; Clara Eskenazi; Celine Bourdon; Cindie Courtin; Bruno Megarbane; Cynthia Marie-Claire; Nadia Benturquia
作者单位Université Paris-Cité, INSERM, Optimisation thérapeutique en neuropharmacologie OTEN, U1144, Paris, 75006, France; Université Paris-Cité, US 25 Inserm – UAR 3612 CNRS, BioSTM, Paris, France; Lariboisière Hospital, Department of Medical and Toxicological Critical Care, Paris, France
BLA astrocytes are associated with withdrawal somatic signs during high-dose naloxone-precipitated morphine withdrawal revealed by 3D-AI behavioral analysis
作者Zhangyin Cai; Kaiman Chang; Rong Fan; Yuanqi Chen; Ke Xu; Qianru Shen; Tzu Yu Sun; Yaxian Wen; Yu Yuan; Siying Kuang; Xin Luo; Xiaoman Su; Ting Ye; Ting Xia; Hao Yang; Juan Wang; Hai Lu; Yuan Han; Ping Zheng; Bin Lai; Ming Chen
作者单位State Key Laboratory of Brain Function and Disorders and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Department of Neurology of Zhongshan Hospital, Department of Anesthesiology of Eye & ENT Hospital, Fudan University, Shanghai, 200032, China; College of Basic Medicine, Jining Medical University, Jining, 272067, China
Intrathecal semaglutide attenuates burn injury-induced pain in mice through a spinal GLP-1R-linked enkephalin/δ-opioid receptor pathway
作者Yongtao He; Jie Gao; Yongpeng Liu; Shuyuan Wu; Junzhe Kuang; Dan Chen; Biao Xu; Mengna Zhang; Quan Fang
作者单位Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, and State Key Laboratory of Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, 199 Donggang West Road, Lanzhou, 730000, PR China
Nitrogen gas-derived cold atmospheric plasma suppresses pruritus through modulation of peripheral sensory neurons and keratinocytes
作者Nana Komai; Yuta Kaga; Mao Kaneki; Masaki Nagane; Masashi Nakamura; Kenichiro Miyasato; Yu Nagahara; Hideaki Kai; Eiji Miyamoto; Akira Morooka; Masahiko Nagata; Tomoki Fukuyama
作者单位School of Veterinary Medicine, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara-shi, Kanagawa, Japan; Center for Human and Animal Symbiosis Science, Azabu University, 1-17-71, Fuchinobe, Chuo-ku, Sagamihara-shi, Kanagawa, Japan; Sekisui Chemical Co., Ltd., 2-10-4 Toranomon, Minato-ku, Tokyo, Japan; Monolith Incubation, LLC., 310 Bldg, 672 Tominaga-cho, Horikawa-nishiiru, Takatsuji-dori, Shimogyo-ku, Kyoto, Japan; Animal Specialist Center (ASC)., 4-1-39, Higashi-machi, Jindaiji, Chofu, Tokyo, Japan
Study on the role and mechanism of P2X4 receptor in allergic contact dermatitis in mice
作者Yuxin Yang; Xiaoqian Ma; Shipan Liu; Shanshan Tang; Yuanyuan Zhang; Yeqing Liu; Guodong Li; Yun Gao; Shangdong Liang
作者单位School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, 330006, China; Class 2103, First Clinical Medical College of Nanchang University, Nanchang, 330006, China
Intraperitoneal administration of adenosine A2A receptor antagonist reduces neuroinflammatory and antioxidant responses in GM2 gangliosidosis mouse model
作者Nurselin Ates; Volkan Seyrantepe
作者单位Izmir Institute of Technology, Department of Molecular Biology and Genetics, Urla, Izmir, Turkey; Izmir Institute of Technology, IYTEDEHAM, Urla, İzmir, Turkey
Subunit-specific roles of NR2A and NR2B in the trigeminal ganglion contribute to orofacial neuropathic pain via distinct molecular cascades
作者Qin-Xuan Song; Yue-Yan Cen; Meng-Fei Dai; Xin-Lin Gao; Fei Liu; Jun-Yu Chen; Chun-Jie Li; Cheng Zhou; Yan-Yan Zhang; Jie-Fei Shen
作者单位State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China; Department of Prosthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China; Department of Head and Neck Oncology, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China; Laboratory of Anesthesia and Critical Care Medicine, Translational Neuroscience Center, West China Hospital of Sichuan University, Chengdu, Sichuan, 610041, China
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