生物学
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Induced degradation of Ufd1 reveals regulation of cohesin by the VCP/p97 Ufd1-Npl4 complex
作者Daniella Munro; Maike Reinders; Aikaterini Pravi; Johannes van den Boom; Pinki Gahlot; Ekaterina Isaakova; Caio AB Oliveira; Dominik Boos; Petra Beli; Hemmo Meyer
作者单位1. Molecular Biology I, Center of Medical Biotechnology, Faculty of Biology, University of Duisburg-Essen; 2. Molecular Genetics II, Center of Medical Biotechnology, Faculty of Biology, University of Duisburg-Essen; 3. Institute of Molecular Biology (IMB); 4. Institute of Developmental Biology and Neurobiology (IDN), Johannes Gutenberg-Universität, Mainz, Germany
Single nucleus multiomics reveals an early inflammatory response to high-fat diet in mouse islets
作者Isabell VS Ernst; Lasse Lehtonen; Freja L Nielsen; Morten F Ebbesen; Sille M Nilsson; Ann-Britt Marcher; Susanne Mandrup; Jesper GS Madsen
作者单位1. Functional Genomics and Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark; 2. Danish Molecular Biomedical Imaging Center (DaMBIC), Department of Biochemistry and Molecular Biology, University of Southern Denmark; 3. Center for Functional Genomics and Tissue Plasticity (ATLAS), Odense M, Denmark; 4. Center for Adipocyte Signaling (ADIPOSIGN), Odense M, Denmark; 5. The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Proliferation and differentiation in intestinal organoids are balanced by ligand-modulated EGFR trafficking
作者Mario O Caracci; Sabrina Seidler; Luis M Muñoz-Nava; Birga Soetje; Kirsten Michel; Philippe IH Bastiaens
作者单位1. Department of Systemic Cell Biology, Max Planck Institute for Molecular Physiology
Interleukin-1 mediates innate immune signaling and antiviral defense in islets
作者Jacob T Bartosiak; Polly A Hansen; Khanmi Kasomva; Sridhar Rao; John A Corbett
作者单位1. Department of Biochemistry, Medical College of Wisconsin; 2. Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin; 3. Hematopoiesis and Immunology Program, Versiti Blood Research Institute, Milwaukee, WI, USA; 4. Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin; 5. Division of Hematology/Oncology/Transplantation, Department of Pediatrics, Medical College of Wisconsin
Single-cell chromatin profiling reveals relapse-related priming in pediatric acute myeloid leukemia
作者Boyu Cui; Minghui Lei; Liwei Liu; Mingxin Shu; Furong Yu; Kai Yang; Yin Pan; Yunhong Song
作者单位1. Department of Medical Technology, Anhui Institute of Medicine, Hefei, China; 2. Department of Hematology, The First Affiliated Hospital, Zhejiang University College of Medicine; 3. Key Laboratory of Hematopoietic Malignancies, Diagnosis and Treatment, Zhejiang, China; 4. School of Biological and Environmental Engineering, Chaohu University
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