医学
Paper Review Records
全部论文审稿周期
12 篇有效样本 · 按发表日期由新到旧排列
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New antifungal and less toxic zwitterionic derivatives of 26-membered polyene antibiotic – pimaricin containing N -benzyl and N -alkyl moieties and their molecular mechanism
作者Ewelina Smolarz; Adam Buczkowski; Wojciech Schilf; Anita Ciesielska; Paweł Stączek; Piotr Ruszkowski; Maria Gdaniec; Franz Bartl; Piotr Przybylski
作者单位1. Faculty of Chemistry, Adam Mickiewicz University; 2. Department of Physical Chemistry, Faculty of Chemistry, University of Lodz; 3. Institute of Organic Chemistry, Polish Academy of Sciences; 4. Department of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz; 5. Department of Pharmacology, Poznan University of Medical Sciences; 6. Institut für Biologie, Humboldt Universität zu Berlin
Cryo-EM structure-based discovery of etravirine as a specific inhibitor of PRMT5/pICln protein-protein interaction for prostate cancer treatment
作者Zhixia Chi; Xueyong Xu; Zhihang Shen; Xuehong Deng; Bennett D. Elzey; Chenglong Li; Wen Jiang; Chang-Deng Hu
作者单位1. Department of Chemistry, Purdue University; 2. Purdue University Interdisciplinary Life Sciences Graduate Program, Purdue University; 3. Department of Biological Sciences, Purdue University; 4. Department of Medicinal Chemistry, College of Pharmacy, University of Florida; 5. Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University; 6. Department of Comparative Pathobiology, Purdue University; 7. Purdue Institute for Cancer Research, Purdue University; 8. Department of Biochemistry and Molecular Biology, Pennsylvania State University
Design of aptamer peptides for immunomodulation
作者Arpan Chowdhury; Prajesh Shrestha; Vivekanandan Subramanian; Venkatesh Mayandi; Mukesh Mahajan; Seetharama D. Jois
作者单位1. Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University; 2. Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky; 3. Department of Chemistry and Biochemistry, University of California San Diego
Exploration of novel hydroxamic acid-based candidates integrating chalcone scaffold cap as multitarget HDAC inhibitors: design, anti-prostatic cancer assessment, in silico docking and molecular dynamic simulation
作者Aya I. Abd El-hameed; Ibrahim M. Salem; Rasha M. Allam; Mariem M. Arafat; Hossameldin A. Aziz; Zuhier A. Awan; Tarek S. Ibrahim; Omar Alshazly; Eman A. M. Beshr; Stefan Bräse; Mamdouh F. A. Mohamed
作者单位1. Depatment of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University; 2. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sphinx University; 3. Pharmacology Department, Medical and Clinical Research Institute, National Research Centre; 4. Cell Culture Unit, Life Science Division, Nawah-Scientific Inc; 5. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, New Valley University; 6. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, New Valley National University; 7. Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University; 8. Department of Organic Chemistry, Faculty of Pharmacy, King Abdulaziz University; 9. Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University; 10. Medicinal Chemistry Department, Faculty of Pharmacy, Minia National University; 11. Institute for Biological and Chemical System, Karlsruhe Institute of Technology
Inhibition effects and binding interactions of epigallocatechin and gallocatechin on tyrosinase and their anti-melanogenesis activity
作者Jianjun Zhang; Zheng Shi; Jiang Li; Kaiming Li; Fan Wu; Min Zhao; Rui Xie; Hongbin Luo
作者单位1. The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine)
Identification of a candidate PRODH allosteric inhibitor MBTP-15324: modulation of proline metabolite profiles and ECM-associated gene-expression changes in lung cancer cells
作者Yuxuan Zhou; Dingyuan Bai; Zhihan Li; Ciqin Li; Chunqiong Li; Mengyao Chen; Cheng Guo; Jun Yan; Yonglong Han; Quanjun Yang
作者单位1. College of Food Science and Technology, Shanghai Ocean University; 2. Department of Pharmacy, Shanghai Sixth People’s Hospital Affiliated Shanghai Jiao Tong University School of Medicine; 3. School of Biomedical Engineering, Donghua University; 4. School of Life Sciences, Beijing University of Chinese Medicine; 5. Institute of Molecular Medicine, College of Future Technology, Peking University
Conformationally constrained 6‑aryl‑1‑(3,4,5‑trimethoxyphenyl)-1 H -pyrazolo[3,4‑b]pyrazines as novel microtubule destabilizers: design, synthesis, and antitumor evaluation
作者Zhu Guo; Yujing Zhang; Ping Zou; Caiyun Sun; Liya Cui; Gang Wang; Chao Wang
作者单位1. Department of Spinal Surgery, The Affiliated Hospital of Qingdao University; 2. The Affiliated Cardiovascular Hospital of Qingdao University, Qingdao University; 3. The Affiliated Hospital of Qingdao University, Qingdao University; 4. Qingdao Cancer Institute, Qingdao University
Novel 6-aryl-1-(3,4,5-trimethoxyphenyl)-1 H -pyrazolo[3,4-d]pyrimidine derivatives: design, synthesis, and biological evaluation as potent tubulin polymerisation inhibitors with anticancer activity
作者Jiake Gao; Yujing Zhang; Rui Qu; Qianqian Xu; Zhenjuan Sun; Liya Cui; Chao Wang
作者单位1. Department of Sports Medicine, The Affiliated Hospital of Qingdao University; 2. The Affiliated Cardiovascular Hospital of Qingdao University, Qingdao University; 3. Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University; 4. Health Management Center, Qingdao Women and Children’s Hospital, Qingdao University
Structure-based screening and identification of a novel Aurora-A-targeting peptide with antiproliferative activity against prostate cancer cells
作者Bei-Bei Huang; Haijing Jiang; Yaozhi Hu; Jia-Jia Ge; Xiaohao Liu
作者单位1. Drug Clinical Trial Facility Office, The Affiliated Hospital of Xuzhou Medical University; 2. Department of Pharmaceutical Analysis, China Pharmaceutical University
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