医学
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Down Syndrome Alters Type III IFN and Proinflammatory Airway Epithelial Responses to Respiratory Syncytial Virus Infection
作者Elizabeth Chorvinsky; Surajit Bhattacharya; Betelehem Solomon Bera; Allison Welham; Karim Ismat; Claire M. Lawlor; Diego Preciado; Jose L. Gomez; Hiroki Morizono; Dinesh K. Pillai; Maria J. Gutierrez; Jyoti K. Jaiswal; Gustavo Nino
作者单位1. Division of Pediatric Pulmonary and Sleep Medicine and; 2. Center for Genetic Medicine Research, Children’s National Research Institute, Washington, District of Columbia; 3. School of Medicine and Health Sciences, George Washington University, Washington, District of Columbia; 4. Division of Pediatric Otorhinolaryngology, Children’s National Hospital, Washington, District of Columbia; 5. Pulmonary, Critical Care and Sleep Medicine Section, Yale University, New Haven, Connecticut; and; 6. Division of Pediatric Allergy, Immunology and Rheumatology, Johns Hopkins University, Baltimore, Maryland
Extracellular Vesicles Contribute to the Pathophysiology and Progression of Pleural Fibrosis by Promoting Mesothelial-to-Mesenchymal Transition and Neoangiogenesis
作者Kaushik Das; Wenyi Qin; Ann Jeffers; Shuzi Owens; Luis Destarac; Steven Idell; L. Vijaya Mohan Rao; Torry A. Tucker; Shiva Keshava
作者单位1. Department of Cellular and Molecular Biology; 2. Biotechnology Research and Innovation Council–National Institute of Biomedical Genomics, Kalyani, India; 3. Department of Pulmonology, and; 4. Texas Lung Injury Institute, The University of Texas Health Science Center at Tyler, Tyler, Texas; and
von Willebrand Factor Deficiency Inhibits Endothelial-to-Mesenchymal Transition to Attenuate Pulmonary Fibrosis
作者Wenjie Wang; Shiyi Chen; Zhuyi Xi; Yuan Si; Yi Liu; Jing Chen; Bingshun Wang; Di Zhu; Likun Gong
作者单位1. Department of Pharmacology, School of Pharmacy, Fudan University, Shanghai, China; 2. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China; and; 3. School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China; 4. Department of Biostatistics, Clinical Research Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China
IFN-Mediated Bronchial Epithelium Cellular Senescence in Chronic Obstructive Pulmonary Disease
作者Hong Guo-Parke; Oisin Cappa; Dermot A. Linden; Ben S. Barksby; Rachel A. Burgoyne; Lee A. Borthwick; Andrew J. Fisher; Sinead Weldon; David A. Simpson; Clifford C. Taggart; Joseph C. Kidney
作者单位1. Airway Innate Immunity Research Group, Wellcome Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queens University Belfast, Belfast, United Kingdom; 2. Newcastle Fibrosis Research Group, Biosciences Institute, and; 3. Transplantation and Regenerative Medicine, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom; 4. Institute of Transplantation, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; and; 5. Department of Respiratory Medicine, Mater Hospital Belfast, Belfast, United Kingdom
IL-33 Induces a Protective Response against Irritant-induced Airway Inflammation and Dysfunction
作者Utako Fujii; Tomotaka Nishizawa; Yumiko Ishii; Emily Nakada; Kosuke Makita; Rui Sun; Toby McGovern; Arina Morozan; Rohin Chakraborty; James G. Martin
作者单位1. Meakins–Christie Laboratories, McGill University Health Centre Research Institute, Montreal, Quebec, Canada; and; 2. Department of Medicine, McGill University, Montreal, Quebec, Canada
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