医学
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The crosstalk between PFKFB3 and RSPO2 drives sepsis-induced lung injury by coupling metabolic rewiring to macrophage inflammation
作者Yao Wang; Juan Zeng; Xiang Dai; Rui Peng; Dan Wang
作者单位Department of Anesthesiology, The Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China; Department of Anesthesiology, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China; Department of Orthopedic Surgery, The Affiliated Nanhua Hospital, Hengyang Medical School, University of South China, Hengyang, 421001, Hunan, China
Microbiota-derived tryptophol attenuates chronic stress-induced pain- and depression-like phenotypes in female mice via colonic aryl hydrocarbon receptor signaling through reduced neuroinflammation
作者Yueyang Xin; Shaodi Guan; Shaomeng Si; Jie Dong; Siqi Zhou; Yun Liu; Hui Xu
作者单位Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Qiaokou District, Wuhan 430030, China
Forsythiaside B alleviates DOX-induced myocardial injury by enhancing the interaction between HSP90AA1 and CYP1A1 to inhibit ferroptosis
作者Sailing Hu; Lingchun Lv; Zhouqing Huang
作者单位Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, No. 1 Fanhaixi Road, Ouhai District, WenZhou, 325000, China; Department of Cardiology, the Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Central Hospital, 289 Kuocang Road, Liandu District, Lishui City, 323000, China
Liposomal nanoparticle mediated chemo-phototherapy for breast cancer ablation via boldine driven metabolic reprogramming
作者Pramit Kumar Ghosh; Sajmina Khatun; Sandip Das; Md. Sadik Ali; Deeksha Trivedi; Rounik Karmakar; Sandipan Ray; Aravind Kumar Rengan
作者单位Department of Biomedical Engineering, Indian Institute of Technology Hyderabad, Kandi, Telangana, 502284, India; Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana, 502284, India
Identification of extracellular matrix-associated signatures to establish a risk model in rheumatoid arthritis and osteoarthritis through transcriptomic analysis
作者Biaojie Huang; Yuhan Huang; Ru Lv; Weikai Wang; Zhihao Hu; Guibo Li; Chen Wei; Xi Chen; Zhengdong Li; Xue Zhang
作者单位MOE Key Laboratory of Freshwater Fish Reproduction and Development, School of Life Sciences, Southwest University, Chongqing 400715, China; BGI Research, Chongqing 401329, China; Precision Medical Center, Guangyuan Central Hospital, Guangyuan, 628000, China; BGI College & Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450000, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China; BGI Research, Shenzhen 518083, China; State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Shenzhen 518083, China
PARP7 enhances doxorubicin-induced cardiomyocyte ferroptosis and cardiotoxicity by ADP-ribosylation-dependent suppression of GPX4 activity
作者Yiting Lyu; Lintao Wang; Xiaowen Shi; Yang Li; Ke Xu; Jian Sheng; Xin Zhong; Huihui Xie; Jiajun Xu; Jibo Han
作者单位The Key Laboratory, the Second Affiliated Hospital of Jiaxing University, Jiaxing, 314000, Zhejiang, China; Department of Cardiology, the Second Affiliated Hospital of Jiaxing University, Jiaxing, 314000, Zhejiang, China; Department of Cardiology, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, 210008, Jiangsu, China
Elevated circulating AIF1L as a cell-free RNA biomarker of preeclampsia impairs trophoblast function via mitochondrial dysregulation
作者Yinlong Chen; Wenli Zhan; Ke Shen; Manqing Peng; Qingliang Zheng
作者单位Biological Laboratory of Hetao Cooperation Zone, the Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, China
Artificial intelligence-assisted proteomic signatures for discriminating malignant from benign pulmonary nodules
作者Juan Luo; Qiongye Dong; Jianyi Yang; Hui Shan; Qianqian Zhong; Yongjian Zhang; Guangxi Wang; Jixian Liu; Yuxin Yin
作者单位Precision Medicine Institute, Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518036, China; Thoracic Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518036, China; Medical Examination Department, Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518036, China; Institute of Systems Biomedicine, Department of Pathology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, China
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