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Effect of Vutrisiran According to Baseline Tafamidis Use in Transthyretin Amyloidosis With Cardiomyopathy: Insights From HELIOS-B
作者Yasuhiro Hamatani; Brian L. Claggett; Sarah A.M. Cuddy; Nitasha Sarswat; Joban Vaishnav; Martha Grogan; Mathew S. Maurer; Ronald M. Witteles; Esther Gonzalez-Lopez; Pablo Garcia-Pavia; Farooq H. Sheikh; Brian M. Drachman; Alisa Kosheleff; Sameer Bansilal; Julian D. Gillmore; Marianna Fontana; Scott D. Solomon
作者单位Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; National Hospital Organization Kyoto Medical Center, Kyoto, Japan; Division of Cardiovascular Medicine, University of Chicago Medicine, Chicago, Illinois, USA; Johns Hopkins Hospital, Baltimore, Maryland, USA; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA; Division of Cardiology, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA; Stanford University School of Medicine, Stanford, California, USA; Hospital Universitario Puerta de Hierro Majadahonda, IDIPHIM, CIBERCV, and Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain; MedStar Heart and Vascular Institute/Georgetown University School of Medicine, Washington, DC, USA; Penn Presbyterian Medical Center, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA; National Amyloidosis Centre, UCL, Division of Medicine, Royal Free Hospital, London, United Kingdom
Influence of Disease-Modifying Therapy on the Efficacy of Vutrisiran in Transthyretin Cardiac Amyloidosis
作者Arielle Abovich; Marianna Fontana; Brian Claggett; Julian D. Gillmore; Francesco Cappelli; Amrut V. Ambardekar; Caroline Morbach; Pablo Garcia-Pavia; Ronald M. Witteles; Mathew S. Maurer; Patrick Y. Jay; Alisa Kosheleff; Sameer Bansilal; Scott D. Solomon
作者单位Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; National Amyloidosis Centre, Division of Medicine, University College London, Royal Free Hospital, London, United Kingdom; Bis Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy; Tuscan Amyloidosis Referral Center Careggi University Hospital, Florence, Italy; Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA; Department of Clinical Research and Epidemiology, Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany; Department of Medicine I, University Hospital Würzburg, Würzburg, Germany; Department of Cardiology, Hospital Universitario Puerta de Hierro Majadahonda, Health Research Institute of the Puerta de Hierro Majadahonda-Segovia de Arana, Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBER-CV), and Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, USA; Columbia University Irving Medical Center, New York, New York, USA; Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA
AI-ECG Detection of Structural Heart Disease in the Community Setting
作者Timothy J. Poterucha; John Weston Hughes; Michael I. Brener; Michael L. Chuang; Nadira B. Hamid; Clayton Snyder; Julia Thompson; Jena Ungarten; Kayo Takahashi; Brian R. Lindman; Francisco Alberto Roedan Oliver; Joshua Finer; Dustin Hartzel; Heidi Hartman; Aaron Long; Daniel Rocha; Paloma Malta; Michelle Castillo; Ramon Pimentel Ricart; Jeffrey A. Ruhl; David vanMaanen; Albert J. Rogers; Marco Perez; Olivier Tastet; Robert Avram; Raphael Nishimura; Juan F. Granada; Michael J. Mack; Martin B. Leon; Pierre Elias; David J. Cohen
作者单位Department of Cardiology, Mayo Clinic, Rochester, Minnesota, USA; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA; Cardiovascular Research Foundation, New York, New York, USA; Division of Cardiology, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA; Structural Heart and Valve Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA; NewYork-Presbyterian Hospital, New York, New York, USA; Division of Cardiovascular Medicine and Cardiovascular Institute, Stanford University School of Medicine, Stanford, California, USA; HeartWise.ai, Department of Medicine, Montreal Heart Institute, Montreal, Quebec, Canada; Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA; Department of Cardiothoracic Surgery, Baylor Scott & White Health, Dallas, Texas, USA; St. Francis Hospital, Roslyn, New York, USA
Rethinking Disease Progression in Transthyretin Amyloid Cardiomyopathy: Toward Mechanism-Specific Monitoring and Therapeutic Response Assessment
作者Marianna Fontana; Scott D. Solomon; Philip N. Hawkins; Julian D. Gillmore
作者单位National Amyloidosis Centre, University College London, Royal Free Campus, London, United Kingdom; Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
Timing, Translation, and Preparedness
作者Tobias Tritschler; Valentin Fuster; Patrick R. Lawler; Michael E. Farkouh; Caterina E. Marx; Matthew D. Neal; Michelle Sholzberg; Alex C. Spyropoulos; Steven Y.C. Tong; Nuria Muñoz-Rivas; Marc Blondon; Jeffrey S. Berger; Behnood Bikdeli; Marco Cattaneo; Mary Cushman; Mark Goldin; Ewan C. Goligher; Judith S. Hochman; Peter Jüni; Zoe K. McQuilten; Nuccia Morici; Parham Sadeghipour; Balasubramanian Venkatesh; Stéphane Zuily; Alain Amstutz; Drahomir Aujesky; Marc Carrier; Robin V. Hofstetter; Srinivas Murthy; Marc Rodger; Leslie Skeith; Areti A. Veroniki; Brian Hutton; Ryan Zarychanski; Gregg W. Stone; Grégoire Le Gal
作者单位Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Inflammation and Chronic Disease Program, University of Ottawa, Ottawa, Ontario, Canada; Icahn School of Medicine at Mount Sinai, Mount Sinai Fuster Heart Hospital, New York, New York, USA; Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain; Cardiology and Critical Care Medicine, University Health Network and University of Toronto, Toronto, Ontario, Canada; Cardiology and Critical Care, McGill University Health Centre, and McGill University, Montreal, Quebec, Canada; Peter Munk Cardiac Centre, University of Toronto, Toronto, Ontario, Canada; Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, California, USA; Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA; Departments of Medicine, and Laboratory Medicine and Pathobiology, Li Ka Shing Knowledge Institute, St Michael’s Hospital, University of Toronto, Toronto, Ontario, Canada; Northwell Health at Lenox Hill Hospital Department of Medicine, New York, New York, USA; The Feinstein Institutes for Medical Research, New York, New York, USA; Victorian Infectious Diseases Service, The Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Melbourne Centre for Clinical Trials, School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia; Department of Internal Medicine, Infanta Leonor University Hospital, Complutense University of Madrid, Madrid, Spain; Faculty of Medicine and Geneva University Hospitals, Division of Angiology and Haemostasis, Geneva, Switzerland; Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA; Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; Yale-New Haven Hospital/Yale Center for Outcomes Research and Evaluation (CORE), New Haven, Connecticut, USA; Fondazione Arianna Anticoagulazione, Bologna, Italy; Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom; Monash University, Melbourne, Victoria, Australia; Monash Health, Melbourne, Victoria, Australia; IRCCS Fondazione Don Gnocchi, ETS, Milan, Italy; Vascular Disease and Thrombosis Research Center, Rajaie Cardiovascular Institute, Tehran, Iran; University of Queensland, Brisbane, Queensland, Australia; The George Institute for Global Health, Sydney, New South Wales, Australia; The George Institute for Global Health, Delhi, India; Gold Coast University Hospital, Southport, Queensland, Australia; University of New South Wales, Sydney, New South Wales, Australia; Department of Vascular Medicine, University Hospital of Nancy, Nancy, France; CLEAR Methods Center, Division Clinical Epidemiology, Department of Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland; Oslo Center for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom; Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada; Department of Medicine, McGill University, McGill University Health Center, Montreal, Quebec, Canada; Division of Hematology and Hematological Malignancies, University of Calgary, Calgary, Alberta, Canada; Center for Evidence Synthesis in Health, Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA; Knowledge Translation Program, Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto, Ontario, Canada; Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada; Methodological and Implementation Research, The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; Department of Internal Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada
Myocardial Scar Assessment Using Artificial Intelligence-Powered Contrast-Free MRI
作者Qiang Zhang; Di Zhou; Patrick Thompson; Georgios Vavillis; Thomas Anderton; Rajib Ahmed; Ricardo A. Gonzales; Huaying Zhang; Wai Yan Ryana Fok; Daniel Atkinson; Katharine E. Thomas; Andrew Lewis; Oliver Rider; Keith M. Channon; Stefan Neubauer; Sven Plein; Minjie Lu; Peter P. Swoboda; Stefan K. Piechnik; Vanessa M. Ferreira
作者单位Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, United Kingdom; Department of Magnetic Resonance Imaging, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Centre for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Department of Biomedical Imaging Science, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom
Effects of Finerenone on Sudden Death Across the Cardio-Kidney-Metabolic Landscape
作者Alberto Foà; Maria A. Pabon; Gerasimos Filippatos; Brian L. Claggett; Zi Michael Miao; Pardeep S. Jhund; Alasdair Henderson; Meike Brinker; Andrea Lage; Lucas Hofmeister; Yoriko De Sanctis; Carolyn S.P. Lam; Michele Senni; Sanjiv J. Shah; Adriaan A. Voors; Faiez Zannad; Peter Rossing; Luis M. Ruilope; Stefan D. Anker; Bertram Pitt; Rajiv Agarwal; John J.V. McMurray; Scott D. Solomon; Muthiah Vaduganathan; Akshay S. Desai
作者单位Heart Failure and Transplant Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece; BHF Glasgow Cardiovascular Research Centre, School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, United Kingdom; Bayer AG, Research & Development, Pharmaceuticals, Wuppertal, Germany; Cardiology and Nephrology Clinical Development, Bayer SA, São Paulo, Brazil; Bayer AG, Global Medical Affairs, Berlin, Germany; Bayer U.S. LLC, Research & Development, Pharmaceuticals, Whippany, New Jersey, USA; National Heart Centre Singapore and Duke-National University of Singapore, Singapore; University of Milano-Bicocca, Papa Giovanni XXIII Hospital, Bergamo, Italy; Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; University of Groningen, Groningen, the Netherlands; University of Lorraine, Nancy, France; Steno Diabetes Center Copenhagen and University of Copenhagen, Copenhagen, Denmark; Hospital 12 de Octubre, Madrid, Spain; Department of Cardiology, German Heart Center Charité, German Centre for Cardiovascular Research partner site Berlin, Charité Universitätsmedizin, Berlin, Germany; University of Michigan, Ann Arbor, Michigan, USA; Indiana University School of Medicine, Indianapolis, Indiana, USA
Comprehensive Long-Term Changes in Cardiovascular Risk Biomarkers With Tirzepatide
作者Naveed Sattar; Bruno Linetzky; Giacomo Ruotolo; Subodh Verma; Harald Sourij; Hui Wang; Kadie Vanderman; Jonathan M. Wilson; Ryan M. Griffin; Adam Stefanski; Paul M Ridker
作者单位School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, United Kingdom; Eli Lilly and Company, Indianapolis, Indiana, USA; Division of Cardiac Surgery, Li Ka Shing Knowledge Institute of St Michael’s Hospital, Unity Health Toronto, University of Toronto, Toronto, Ontario, Canada; Cardiometabolic Trials Unit, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria; TechData Service Company, LLC, King of Prussia, Pennsylvania, USA; Syneos Health, Inc, Morrisville, North Carolina, USA; Center for Cardiovascular Disease Prevention, Divisions of Preventive Medicine and Cardiovascular Diseases, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Monogenic ALB Variants as Determinants of Severe Hypercholesterolemia
作者Alexander S.F. Berry; Dylan Cawley; Andrea Hattenberger; Alexander R. Chang; Robert A. Hegele; Samuel S. Gidding; Matthew T. Oetjens
作者单位Department of Developmental Medicine, Geisinger, Lewisburg, Pennsylvania, USA; Department of Genomic Health, Geisinger, Danville, Pennsylvania, USA; Geisinger, Danville, Pennsylvania, USA; Department of Population Health Sciences, Geisinger, Danville, Pennsylvania, USA; Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada
Long-Term Outcomes of a Drug-Eluting Resorbable Scaffold vs Angioplasty in Infrapopliteal Chronic Limb-Threatening Ischemia
作者Sahil A. Parikh; Brian G. DeRubertis; Marc P. Bonaca; Prakash Krishnan; Richard H. Pin; Jen-Kuang Lee; David C. Metzger; Raghu Kolluri; Mehdi H. Shishehbor; Andrew H. Holden; Osamu Iida; Ehrin Armstrong; Steven W.C. Kum; David J. O’Connor; Danielle R. Bajakian; Lawrence A. Garcia; Shih-Wa Ying; Jin Wang; Karine Ruster; Brad J. Martinsen; Zsuzsanna Igyarto; Ramon L. Varcoe
作者单位Division of Cardiology, Columbia University Irving Medical Center, New York, New York, USA; New York Presbyterian–Weill Cornell Medical Center, New York, New York, USA; CPC Clinical Research, Cardiovascular Division, University of Colorado School of Medicine, Aurora, Colorado, USA; Mount Sinai Hospital, New York, New York, USA; Charlton Memorial Hospital, Dartmouth, Massachusetts, USA; Division of Cardiology, Department of Internal Medicine, N ational Taiwan University Hospital, Taipei City, Taiwan; Ballad Health, Kingsport, Tennessee, USA; Syntropic Core Lab and OhioHealth Heart and Vascular, Columbus, Ohio, USA; University Hospitals Harrington Heart and Vascular Institute, Cleveland, Ohio, USA; Auckland Hospital and Auckland University, Grafton, Auckland, New Zealand; Cardiovascular Division, Osaka Keisatsu Hospital, Osaka, Japan; Advanced Heart and Vein Center, Denver, Colorado, USA; Department of Surgery, Changi General Hospital, Singapore; Hackensack University Medical Center, Hackensack, New Jersey, USA; Columbia University Irving Medical Center, New York, New York, USA; Catholic Health Services, St Francis Hospital and Heart Center, Roslyn, New York, USA; Abbott Vascular, Santa Clara, California, USA; The Prince of Wales Hospital and University of New South Wales, Randwick, Australia
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