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120.6平均天数
116中位天数
51最短天数
238最长天数
1,5232025发文量

Paper Review Records

全部论文审稿周期

5 篇有效样本 · 按发表日期由新到旧排列
审稿天数=录用日期-收稿日期;保留 PDF/DOI/网页源链接

52 天

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis

作者
Peter Weber; Rogier Smits; Herman D. Lim; Mounir Andaloussi; Jac Wijkmans; Bas de Boer; Thuy Duong Tran; Barbara Zarzycka; Mabel E. Dekker; Tiffany van der Meer; Rick Riemens; Niels Hauwert; Gabor Wagner; Henry F. Vischer; Matthew J. Chapin; Paul Gomes; Andy Whitlock; Maikel Wijtmans; Rob Leurs; Iwan J. P. de Esch展开收起
作者单位
1. Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Department of Chemistry & Pharmaceutical Sciences, 1190Vrije Universiteit Amsterdam, De Boelelaan 1083, Amsterdam 1081 HV, The Netherlands; 2. Griffin Discoveries BV, De Boelelaan 1083, KA-323, Amsterdam 1081 HV, The Netherlands; 3. Ora, LLC, 138 Haverhill Street, Suite 102, Andover, Massachusetts 01810, United States展开收起
官方全文证据 DOI 网页
146 天

A Subcellular Keap1-Nrf2 Disruption Strategy for Atopic Dermatitis Therapy

作者
Zixi Zhang; Jia Wu; Jingqi Liu; Daniel Shiu-Hin Chan; Chun-Yuen Wong; Jing Wang; Chung-Hang Leung; Wanhe Wang展开收起
作者单位
1. School of Life Science and Technology, 26487Northwestern Polytechnical University, 1 Dongxiang Road, Xi’an, Shaanxi 710072, China; 2. Research & Development Institute of Northwestern Polytechnical University in Shenzhen, 45 South Gaoxin Road, Shenzhen, Guangdong 518057, China; 3. State Key Laboratory of Mechanism and Quality of Chinese Medicine, 59193University of Macau, Taipa, Macao SAR 999078, China; 4. Institute of Chinese Medical Sciences, University of Macau, Taipa, Macao SAR 999078, China; 5. Department of Chemistry, 2152City University of Hong Kong, Kowloon, Hong Kong 999077, China; 6. College of Chemistry and Materials Science, State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, 510632, China展开收起
官方全文证据 DOI 网页
238 天

Development of Covalent Inhibitors of Chikungunya Virus nsP2 Cysteine Protease Enabled by Direct-to-Biology Synthesis and Screening

作者
Zhengjun Cai; Kan Li; Sainetra Sridhar; Haozhou Tan; Hiwot Demssie; Gaungjin Fan; Wenyi Zhang; Bobby Brooke Herrera; Jun Wang展开收起
作者单位
1. Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, United States; 2. Rutgers Global Health Institute, New Brunswick, New Jersey 08901, United States; 3. Department of Medicine, Division of Allergy, Immunology, and Infectious Diseases, and Child Health Institute of New Jersey, 12287Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, United States展开收起
官方全文证据 DOI 网页
116 天

Discovery of Highly Efficacious CRBN-Based KRAS Degraders Targeting Cancers with KRAS G12D and G12V Mutations

作者
Changwei Wang; Prithwish Ghosh; Shicheng Jin; Longchuan Bai; Angelo Aguilar; Donna McEachern; Mi Wang; Qiuxia Li; Bo Wen; Duxin Sun; Shaomeng Wang展开收起
作者单位
1. Department of Internal Medicine, 1259University of Michigan, Ann Arbor, Michigan 48109, United States; 2. Department of Pharmaceutical Sciences, 1259University of Michigan, Ann Arbor, Michigan 48109, United States; 3. Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan 48109, United States; 4. Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States; 5. Department of Pharmacology, University of Michigan, Ann Arbor, Michigan 48109, United States展开收起
官方全文证据 DOI 网页
51 天

The Discovery of GSK3227634: A Potent Inhaled Inhibitor of the KEAP1/NRF2 Protein–Protein Interaction for the Treatment of Chronic Obstructive Pulmonary Disease

作者
James F. Callahan; Thomas G. Davies; Marcus Bantscheff; Sabrina Bedard; Jeffrey Boehm; Catherine Booth-Genthe; Nestor Concha; Roy Copley; Alicia Davis; Roderick Davis; Dirk Eberhard; Joseph Foley; Pearl Flamberg; Nicole C. Goodwin; Tom D. Heightman; Steven R. Katchur; Jeffrey K. Kerns; Casey Kmett; Charles J. Kotzer; Philip Landis; Tindy Li; Derrick Meinhold; Marcel Mülbaier; Hong Nie; Ruth R. Osborn; Torren M. Peakman; Brian Peck; Patricia L. Podolin; Thomas Sweitzer; Hongxing Yan; Paris Ward; Thilo Werner; Lawrence A. Wolfe III; Alison J.-A. Woolford; Zining Wu; Yolanda Sanchez; William L. Rumsey展开收起
作者单位
1. 33139GSK, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States; 2. 2145Astex Pharmaceuticals, 436 Cambridge Science Park, Cambridge CB4 0QA, U.K.; 3. 580818Cellzome GmbH, a GSK Company, Heidelberg 69117, Germany; 4. GSK, Gunnels Wood Road, Stevenage SG1 2NY, Hertfordshire, U.K.展开收起
官方全文证据 DOI 网页

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《融合机器学习与生命周期评价的城市污水处理碳排放预测与优化》

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平均审稿62 天

中位数65 天

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