生物学
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From fragmented workflows to integrated pipelines: Bridging enzymatic DNA synthesis, assembly, and MutS-based error correction
作者Xiaohang Wang; Xinran Zhang; Wenfei Yu; Wenshuang Liu; Jian Xu; Shuangying Jiang; Xiaoyun Lu; Jia Zhang
作者单位University of Jinan, Jinan, Shandong, China; Single-Cell Center, Key Laboratory of Photoelectric Conversion and Utilization of Solar Energy, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong 266101, China; Shandong Energy Institute, Qingdao 266101, China; Qingdao New Energy Shandong Laboratory, Qingdao 266101, China; University of Chinese Academy of Sciences, Beijing 101408, China; Shenzhen Key Laboratory of Synthetic Genomics, Guangdong Provincial Key Laboratory of Synthetic Genomics, State Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Zhonghe Gene Technology Co., Ltd., Tianjin 300308, China
Challenges and opportunities in continuous bioprocessing of lentiviral vectors and adeno-associated viral vectors
作者Alexandra Solis Olivares; Agnes Julia L. Aparte; Dale J. Stibbs; Pedro Silva Couto; Qasim A. Rafiq
作者单位Department of Biochemical Engineering, University College London, Bernard Katz Building, Gower Street, London WC1E 6BT, United Kingdom; Department of Chemical Engineering, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom
Astaxanthin biomanufacturing under hierarchical constraints: Integrating synthetic biology and artificial intelligence for scalable production
作者Jun-Zhuo Zhang; Zi-Yi Nie; Yapki Lau; Ho Huang; Si-Wei Wu; Yu-Te Chen; Dan Huang; Bao-Yun Liang; Li-Gong Zou; Srinivasan Balamurugan; Wei-Dong Yang; Hong-Ye Li; Da-Wei Li
作者单位Key Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou 510632, China; Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur 603203, India
Intrinsic apoptosis in nematodes: Evolutionary plasticity and biotechnological opportunities
作者Marc Kaethner; Neil D. Young; Erinna F. Lee; W. Douglas Fairlie; Brad E. Sleebs; Bill C.H. Chang; Robin B. Gasser
作者单位Department of Veterinary Biosciences, Melbourne Veterinary School, The University of Melbourne, Parkville, VIC, Australia; Department of Biochemistry and Chemistry, School of Agriculture, Biomedicine and Environment, La Trobe University, Bundoora, VIC, Australia; La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC, Australia; Olivia Newton-John Cancer Research Institute, Heidelberg, VIC, Australia; School of Cancer Medicine, La Trobe University, Bundoora, VIC, Australia; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia
The evolving landscape of recombinant adeno-associated virus (rAAV) manufacturing: Engineering vector plasmids for upstream production
作者Minji Lee; Jung Eun Park
作者单位Department of Biomaterials Engineering, CHA University, Seongnam 13488, Republic of Korea; Department of Physiology, Graduate school of medicine, CHA University, Pocheon 11160, Republic of Korea; Cell Therapy Research Division, CHA R&D institute, Seongnam 13488, Republic of Korea
Closing the loop: AI-driven integration of multi-omics and phenomics for systematic resilient crop engineering
作者Zheng Yang; Tong Tang
作者单位School of Agriculture and Biomanufacturing, Zhengzhou University, Zhengzhou 450001, China; Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China; Department of Computer Science and Information Technologies, Elviña Campus, University of A Coruña, 15001 A Coruña, Spain
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