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Composite outcome measures that successfully differentiate active treatments from placebo in psoriatic arthritis trials: a GRAPPA-OMERACT systematic review and network meta-analysis
作者Tommy K Annfeldt; Mina N Händel; Tobias Haugegaard; Marius Henriksen; Laura C Coates; Alexis Ogdie; William Tillett; Niti Goel; Dafna D Gladman; Ana-Maria Orbai; Maarten de Wit; Vibeke Strand; Philip J Mease; Oliver FitzGerald; Philip S Helliwell; Peter Tugwell; Ying-Ying Leung; Robin Christensen
作者单位Section for Biostatistics and Evidence-Based Research, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark; Research Unit OPEN at Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Denmark; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Medicine/Rheumatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Department of Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath, UK; Royal National Hospital for Rheumatic Diseases, University of Bath, Bath, UK; Patient Research Partner and Department of Medicine, Duke University School of Medicine, Durham, NC, USA; Division of Rheumatology, Department of Medicine, University of Toronto, Toronto, ON, Canada; Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, University Health Network, Toronto, ON, Canada; Psoriatic Arthritis Program, Johns Hopkins Arthritis Center, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; GRAPPA Patient Research Partner, The Netherlands; Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, USA; Swedish Medical Center/Providence St. Joseph Health, Seattle, WA, USA; University of Washington School of Medicine, Seattle, WA, USA; UCD Conway Institute, School of Medicine, University College Dublin, Belfield, Dublin, Ireland.; LIRMM, University of Leeds, Leeds, UK; Department of Medicine, University of Ottawa, Ottawa, ON, Canada; Singapore General Hospital, Singapore, Singapore; Duke-NUS Medical School, Singapore, Singapore; Cochrane Denmark & Centre for Evidence-Based Medicine Odense (CEBMO), Department of Clinical Research, University of Southern Denmark, Denmark
Progression from symptom onset to rheumatoid arthritis: is the trajectory similar in anticitrullinated protein antibody-positive and -negative disease? A comparative longitudinal study
作者Mitra Hosseini Malekroudi; Stijn Claassen; Hanna W. van Steenbergen; Elise van Mulligen; Annette H.M. van der Helm-van Mil
作者单位Department of Rheumatology, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands; Department of Rheumatology, Erasmus University Medical Center, Leiden, Zuid-Holland, The Netherlands
Anti-PAD4 antibodies link autoimmunity to PAD4 with CTL-associated rheumatoid arthritis
作者Kusuma Ananth; Katharine B Moosic; Eduardo Gomez-Banuelos; Hong Wang; Isabel Trejo-Zambrano; Ramona Johnson; Jessica Marie Kirschmann; Tess Deddens; Omar Elghawy; Bryna Shemo; William H Robinson; Donald Kimpel; Clifton O Bingham; David J Feith; Brendan Antiochos; Felipe Andrade; Thomas P Loughran; Erika Darrah
作者单位Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Division of Hematology/Oncology, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA; Division of Immunology and Rheumatology, Stanford School of Medicine, Stanford, CA, USA; The Geriatric Research, Education, and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA; Division of Rheumatology & Immunology, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA
Dual dynamics of persistence and recruitment characterise the ACPA-expressing B cell response in rheumatoid arthritis
作者Renee van de Wetering; Shachi Mujumdar; Linda M. Slot; Arieke S.B. Kampstra; Sanne Kroos; Rian Schopmeijer; Sam Neppelenbroek; Cynthia M. Fehres; Mirjam H.M. Heemskerk; Hans U. Scherer; René E.M. Toes
作者单位Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands
A pathogenic gut lipoglycan drives systemic thromboinflammation in lupus nephritis
作者Abhimanyu Amarnani; Cristobal F. Rivera; Macintosh Cornwell; Tyler Weinstein; Zakia Azad; Susan R.S. Gottesman; Cynthia Loomis; Andy Lee; Nimat Ullah; Joshua Prasad; Mingyang Yi; Laura Cooney; Betsy J. Barnes; Nicolas Gisch; Kelly V. Ruggles; Bhama Ramkhelawon; Gregg J. Silverman
作者单位Division of Rheumatology, Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA; Department of Cell Biology, NYU Grossman School of Medicine, New York, NY, USA; Division of Precision Medicine, Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA; Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA; University of Michigan and Immune Tolerance Network, Ann Arbor, MI, USA; Institute for Molecular Medicine, Feinstein Institutes, New York, NY, USA; Division of Bioanalytical Chemistry, Research Center Borstel, Leibniz Lung Center, Borstel, Germany
Musculoskeletal ultrasound findings in people with asymptomatic hyperuricemia: baseline analysis from the Transitions in Gout Research (TIGER) study using the OMERACT gout ultrasound semiquantitative scoring system
作者Sarah Stewart; Gregory D. Gamble; William J. Taylor; Andrew Harrison; Tony R. Merriman; Borislav Mihov; Anne Horne; Isabel Su; Adwoa Dansoa Tabi-Amponsah; Lisa K. Stamp; Janine Haslett; Tristan Pascart; Mariano Andrés; Maria-Luisa Peral-Garrido; Tuhina Neogi; Eleonora Norkuviene; Janitzia Vazquez-Mellado; John F. Fitzgerald; Lene Terslev; Hilde Berner Hammer; Till Uhlig; Maria-Antonietta D’Agostino; Julia Martin; Mingshu Sun; Changgui Li; Nicola Dalbeth
作者单位Department of Medicine, University of Auckland, Auckland, New Zealand; Department of Medicine, University of Otago Wellington, Wellington, New Zealand; Department of Microbiology and Immunology, University of Otago Dunedin, Dunedin, New Zealand; Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States; Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand; Health New Zealand-Te Whatu Ora, Wellington, New Zealand; Department of Rheumatology, Lille Catholic University, Lille, France; Department of Rheumatology, Dr. Balmis General University Hospital, Miguel Hernández University; Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain; Rheumatology Section, Vinalopo University Hospital, Elche, Spain; Department of Clinical Epidemiology Research and Training, Boston University School of Medicine, Boston, Massachusetts, United States; Rheumatology Department, Lithuanian University of Health Sciences, Kaunas, Lithuania; Department of Rheumatology, Hospital General de México, Mexico City, Mexico; School of Medicine, UCLA Health, Los Angeles, California, USA; Copenhagen Center for Arthritis Research, Rigshospitalet, Glostrup, Denmark; Department of Clinical Medicine, University of Copenhagen, Denmark; Department of Rheumatology, Center for Treatment for Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway; Department of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; Division of Rheumatology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Division of Rheumatology, Università Cattolica del Sacro Cuore, Rome, Italy; Te Toka Tumai Auckland, Health New Zealand – Te Whatu Ora, Auckland, New Zealand; The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China
Human hypofunctional NCF1 variant aggravates salivary gland immunopathology in Sjögren’s disease by promoting switched memory B-cell recruitment and long-lived plasma cell differentiation
作者Xinran Yuan; Xiaodong Qin; Xinjie Wu; Yi Chen; Yujiao Wang; Yulu Zhang; Dong Xie; Yao Liu; Jian Zhao; Joel M. Guthridge; Judith A. James; Christopher J. Lessard; Nan Shen; Lingyun Sun; Betty P. Tsao
作者单位Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, PR China; Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA; Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, PR China; Department of Pathology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, PR China; Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA; Genes and Human Disease Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA; Department of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China
Topoisomerase 1-DNA complexes are preferentially recognised by a subset of anti-topoisomerase 1 autoantibodies and their corresponding B cell receptors in systemic sclerosis
作者Sam Neppelenbroek; Corrie M. Wortel; Danique M.H. van Rijswijck; Marjolein J.A.L. Wetzels; Robbert Q. Kim; Nikki M. Loof; Martina Erbì; E.W. Nivine Levarht; Bart Everts; Albert J.R. Heck; Jeska K. de Vries-Bouwstra; Cynthia M. Fehres; René E.M. Toes; Hans U. Scherer
作者单位Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands; Protein Facility, Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands; Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Center, Leiden, The Netherlands
RA and PsA synovial tissue single-cell analysis demonstrates differential fibroblast populations with distinct phenotypes and functional capacities
作者Órla Tynan; Aenea A.I. Brugman; Conor M. Smith; Mary Canavan; Aoife M. O’Rourke; Achilleas Floudas; Dumitru Anton; Siobhán Wade; Sonia Sundanum; Jean M. Fletcher; Carl Orr; Douglas J. Veale; Ursula Fearon
作者单位Molecular Rheumatology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland; Translational Immunopathology, Schools of Biochemistry and Immunology and Medicine, Trinity College Dublin, Dublin, Ireland; Life Sciences Institute, Dublin City University, Dublin, Ireland; Medical School, University of Ioannina, Ioannina, Greece; EULAR Centre of Excellence, Centre for Arthritis and Rheumatic Diseases, St Vincent’s University Hospital, Dublin, Ireland; School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland
An immunometabolic signature of major depressive disorder in systemic lupus erythematosus
作者Pierre Ellul; Nicolas Tchitchek; Grete Kvedaraviciute; Roberta Lorenzon; Isabelle Melki; Richard Delorme; Michelle Rosenzwajg; David Klatzmann
作者单位Immunology-Immunopathology- Immunotherapy (i3), INSERM, UMR_S 959, Sorbonne Université, Paris, France; Child and Adolescent Psychiatry Department, Robert Debré Hospital, Université Paris Cité, Paris, France; Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Pitié-Salpêtrière Hospital, AP-HP, Paris, France; Department of General Pediatrics, Trousseau Hospital, Sorbonne Université, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France
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