生物学
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Peroxynitrite‐induced structural remodeling and aggregation of hemoglobin under nitroxidative stress
作者Shaik Basha; Aradhika Vijeev; Darshan Chikkanayakanahalli Mukunda; Krishna Kishore Mahato
作者单位1. Department of Biophysics Manipal School of Life Sciences, Manipal Academy of Higher Education Manipal India; 2. Department of Biosciences & Bioengineering Indian Institute of Technology Dharwad Dharwad Karnataka India
ContrastQA: A label‐guided graph contrastive learning‐based approach for protein complex structure quality assessment
作者Lei Zhang; Rui Ding; Xiao Chen; Jie Hou; Dong Si; Yang Wang; Keying Lin; Renzhi Cao
作者单位1. School of Computer Science and Technology, Anhui University Hefei China; 2. Department of Mathematics and Computer Science Hamilton College Clinton New York USA; 3. Department of Computer Science Saint Louis University St. Louis Missouri USA; 4. School of Computing and Software, Washington Bothell University Bothell WA USA; 5. School of Computer Science, Pacific Lutheran University Tacoma WA USA
4‐Ethyl phenyl sulfate binding to human serum albumin
作者Vida Dehghan Niestanak; Jacopo Zattoni; Ryan T. McKay; Marcello Tonelli; Maral Aminpour; Larry D. Unsworth
作者单位1. Department of Biomedical Engineering University of Alberta Edmonton Canada; 2. Department of Chemistry University of Alberta Edmonton Canada; 3. Department of Medicine University of Calgary Calgary Canada; 4. Department of Chemical and Materials Engineering University of Alberta Edmonton Canada
Sequence‐encoded determinants drive distinct early aggregation pathways and different structural outcomes in PNT1 fibrils across Henipavirus members
作者Harshita Sawdekar; Julien Mignon; Frank Gondelaud; Anuja Walimbe; Samrat Mukhopadhyay; Joseph Chamieh; Sonia Longhi
作者单位1. Aix‐Marseille Université, CNRS, Architecture et Fonction des Macromolécules Biologiques (AFMB), UMR 7257 Marseille France; 2. IBMM, University of Montpellier, CNRS, ENSCM Montpellier France; 3. Centre for Protein Science, Design, and Engineering Indian Institute of Science Education and Research (IISER) Mohali Punjab India; 4. Department of Chemical Sciences Indian Institute of Science Education and Research (IISER) Mohali Punjab India; 5. Department of Biological Sciences Indian Institute of Science Education and Research (IISER) Mohali Punjab India
A cryptic allosteric pocket shapes isoform‐selective inhibition of human malic enzymes
作者Ben A. Krinkel; Yuliana Yosaatmadja; Mark D. Slayton; Anita Krinkel; Jack Copping; Jin Heon Jeon; Joyce Eu; Kerslee Kohagen; Amir Ashoorzadeh; Jeff Smaill; Jack Flanagan; Christopher Walker; Sofia D. Merajver; Kerry Loomes; Christopher J. Squire
作者单位1. School of Biological Sciences The University of Auckland Auckland New Zealand; 2. Maurice Wilkins Centre for Molecular Biodiscovery The University of Auckland Auckland New Zealand; 3. Department of Internal Medicine University of Michigan, Michigan Medicine Ann Arbor Michigan USA; 4. Department of Pharmacology and Clinical Pharmacology The University of Auckland Auckland New Zealand; 5. Auckland Cancer Society Research Centre The University of Auckland Auckland New Zealand
Graph identification of proteins in tomograms ( GRIP ‐Tomo) 2.0: Topologically aware classification for proteins
作者Chengxuan Li; August George; Reece Neff; Doo Nam Kim; Trevor Moser; Kate Baldwin; Malio Nelson; Arsam Firoozfar; James E. Evans; Margaret S. Cheung
作者单位1. Department of Physics University of Washington Seattle Washington USA; 2. Environmental Molecular Sciences Division Pacific Northwest National Laboratory Richland Washington USA; 3. Electrical and Computer Engineering North Carolina State University Raleigh North Carolina USA; 4. Biological Sciences Division Pacific Northwest National Laboratory Richland Washington USA
Identification of a key water molecule involved in the macrophage migration inhibitory factor‐catalyzed tautomerization of para ‐hydroxyphenylpyruvate using neutron crystallography
作者Gabriela C. Schröder; Gregg V. Crichlow; Ewelina Jablonowski; Georgios Pantouris; Jay Nix; Naomi Chayen; Flora Meilleur; Elias J. Lolis
作者单位1. Department of Molecular and Structural Biochemistry North Carolina State University Raleigh North Carolina USA; 2. Neutron Scattering Division Oak Ridge National Laboratory Oak Ridge Tennessee USA; 3. Department of Pharmacology Yale University School of Medicine New Haven Connecticut USA; 4. Molecular Biology Consortium, Advanced Light Source Lawrence Berkeley National Laboratory Berkeley California USA; 5. Division of Systems Medicine, Department of Metabolism Digestion and Reproduction, Imperial College London London UK
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