医学
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20 篇有效样本 · 按发表日期由新到旧排列
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Synaptic Mitochondrial Oxidative Stress Contributes to Individual Variability in Age‐Related Cognitive Inflexibility in Mice
作者Rui Yamada; Hirotaka Nagai; Chisato Numa; Yunhui Zhu; Midori Nagai; Kohei Ota; Yusuke Kawashima; Nobuhiko Ohno; Tomoyuki Furuyashiki
作者单位1. Division of Pharmacology, Graduate School of Medicine Kobe University Kobe Japan; 2. Department of Anatomy, Division of Histology and Cell Biology, School of Medicine Jichi Medical University Shimotsuke Japan; 3. Department of Pharmacology Graduate School of Medical and Dental Sciences, Institute of Science Tokyo Tokyo Japan; 4. Department of Applied Genomics Kazusa DNA Research Institute Kisarazu Japan; 5. Division of Ultrastructural Research National Institute for Physiological Sciences Okazaki Japan
Clonal Mosaicism of Mitochondrial DNA Heteroplasmy as a Molecular Clock of Aging
作者Renin Chang; Andy P. Tsai; Boyang Wang; Kuan‐Hao Tsui; Cheng‐Yoong Pang; Chia‐Jung Li
作者单位1. Department of Medical Education and Research Kaohsiung Veterans General Hospital Kaohsiung Taiwan; 2. Center of General Education Cheng Shiu University Kaohsiung Taiwan; 3. Center of General Education Shu‐Zen Junior College of Medicine and Management Kaohsiung Taiwan; 4. Department of Neurology and Neurological Sciences Stanford University School of Medicine Stanford California USA; 5. Sundial Initiative Palo Alto California USA; 6. Department of Obstetrics and Gynecology Kaohsiung Veterans General Hospital Kaohsiung Taiwan; 7. Institute of Biopharmaceutical Sciences National Sun Yat‐Sen University Kaohsiung Taiwan; 8. Department of Medical Research Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Hualien Taiwan; 9. Center for Cell Therapy and Development Hualien Tzu Chi Hospital Hualien Taiwan; 10. National Museum of Marine Biology & Aquarium Pingtung Taiwan
The Secretome Derived From Human Umbilical Cord Mesenchymal Stem Cells Improves Skin Photoaging by Enhancing Mitophagy to Inhibit the cGAS ‐ STING Pathway
作者Tingting Tang; Meifen Lin; Jingjing Yang; Xinyu Yang; Xunhong Xu; Xuan Wang; Yarui Zhang; Qimei Chen; Shan Zhao; Chenhui Guo; Hao Zhang; Min Zhang; Lin Zhang; Xueer Wang
作者单位1. Department of Histology and Embryology, School of Basic Medical Sciences Southern Medical University Guangzhou China; 2. Department of Pathology Wuping County Hospital Longyan Fujian China; 3. School of Public Health Southern Medical University Guangzhou China; 4. Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering Southern Medical University Guangzhou China; 5. NMPA Center for Innovation and Research in Regulatory Science Guangzhou China; 6. Key Laboratory of Functional Proteomics of Guangdong Province, School of Basic Medical Sciences Southern Medical University Guangzhou China
Transmembrane Protein PTCHD4 Is a Novel Regulator of Cellular Senescence and Age‐Related Pathologies
作者Mingyue Wang; Zhaoyun Yang; Qikai Wang; Zeping Li; Zhihua Huang; Le Wang; Xiaoning Sun; Donglin Yu; Wenhua Yu; Xiaoxia Bao; Zebin Mao; Yang Li
作者单位1. Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences Peking University Beijing China; 2. Sino‐Danish College, Sino‐Danish Center for Education and Research University of Chinese Academy of Sciences Beijing China; 3. Key Laboratory of Gastrointestinal Cancer, Ministry of Education, School of Basic Medical Sciences Fujian Medical University Fuzhou Fujian Province China; 4. Department of Clinical Laboratory Peking University First Hospital Beijing China; 5. Affiliated Hospital of Liaoning University of Traditional Chinese Medicine Shenyang Liaoning Province China; 6. Department of Gynecology, Dongzhimen Hospital Beijing University of Chinese Medicine Beijing China; 7. Department of Cell Biology, School of Basic Medical Sciences Peking University Beijing China
Mitochondrial Haplotype Shapes the Trajectory of Ovarian Aging in Genetically Heterogeneous Rats
作者Subhasri Biswas; Hoang V. M. Nguyen; Aubrey Converse; Satoshi Matsuzaki; Michael T. Kinter; Kenneth M. Humphries; Willard M. Freeman; Sarah R. Ocañas; Arlan Richardson; Francesca E. Duncan; Tommy L. Lewis; Michael B. Stout
作者单位1. Aging and Metabolism Research Program Oklahoma Medical Research Foundation Oklahoma City Oklahoma USA; 2. Department of Biochemistry and Physiology, College of Medicine University of Oklahoma Health Sciences Oklahoma City Oklahoma USA; 3. Department of Obstetrics and Gynecology, Feinberg School of Medicine Northwestern University Chicago Illinois USA; 4. Genes & Human Disease Research Program Oklahoma Medical Research Foundation Oklahoma City Oklahoma USA; 5. Oklahoma City Veterans Affairs Medical Center Oklahoma City Oklahoma USA
Sustained Activation of CaMKII Promotes Skeletal Muscle Contractile Dysfunction in Aging
作者Michael R. Bene; Tae Chung; Elizabeth D. Luczak; Gabriel Lopez‐Cecetaite; William A. Fountain; Giovanni Rosales‐Soto; Erick Hernández‐Ochoa; Corina Antonescu; Liliana Florea; Seeun J. Jeong; Emily Elassal; Anne Le; Qian‐Li Xue; Ahmet Hoke; Peter M. Abadir; Qinchuan Wang
作者单位1. Division of Geriatric Medicine and Gerontology, Biology of Healthy Aging Program Johns Hopkins School of Medicine Baltimore Maryland USA; 2. Shirley Ryan AbilityLab Chicago Illinois USA; 3. Department of Physical Medicine and Rehabilitation Northwestern University Chicago Illinois USA; 4. Division of Cardiology Johns Hopkins School of Medicine Baltimore Maryland USA; 5. School of Health and Human Sciences Indiana University Indianapolis Indianapolis Indiana USA; 6. Department of Biochemistry and Molecular Biology, School of Medicine University of Maryland Baltimore Maryland USA; 7. Genetic Resources Core Facility, Computational Bioanalysis Division, and Department of Genetic Medicine Johns Hopkins School of Medicine Baltimore Maryland USA; 8. College of Computer, Mathematical, and Natural Sciences University of Maryland College Park Maryland USA; 9. Gigantest, Inc. Baltimore Maryland USA; 10. Department of Neurology and Neuroscience Johns Hopkins School of Medicine Baltimore Maryland USA
3D Culture Reverses Limbal Niche Cell Replicative Aging via FOSL1 Upregulation
作者Xuying Wang; Shen Li; Zibin Liu; Xinghan Guo; Jiachao Shen; Tianyu Zhou; Shuying Liao; Xiaoyu Huang; Wei Wang; Lingjuan Xu; Xinjie Zang; Guigang Li
作者单位1. Department of Ophthalmology, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China; 2. Hubei Key Laboratory of Otorhinolaryngologic and Ophthalmic Diseases Wuhan Hubei China; 3. Department of Ophthalmology University Hospital of Erlangen, Friedrich‐Alexander‐University of Erlangen–Nuremberg (FAU) Erlangen Germany; 4. Chiemsee Augen Tagesklinik Prien Germany; 5. Department of Ophthalmology Qilu Hospital of Shandong University (Qingdao) Qingdao Shandong China
Twisting the End Game: How Telomere Chromatin Modifications Shape Telomere Maintenance
作者Jie Wang; Yuehui Su; Chao Chen; Yueying Li; Jiajia Han; Liping Du; Liyun Zheng; Ya‐Long Dang; Ying Peng
作者单位1. Department of Ophthalmology The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan China; 2. Sanmenxia Central Hospital Henan University of Science and Technology Sanmenxia Henan China; 3. Sanmenxia Eye Hospital Henan International Joint Laboratory of Glaucoma Aqueous Humor Drainage Sanmenxia Henan China; 4. Henan Institute of Medical and Pharmaceutical Sciences Zhengzhou University Zhengzhou Henan China; 5. Department of Gynecology The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan China; 6. Department of Critical Care Medicine Henan Provincial People's Hospital, Zhengzhou University People's Hospital Zhengzhou Henan China; 7. Department of Infectious Diseases Henan Provincial People's Hospital, Zhengzhou University People's Hospital Zhengzhou Henan China; 8. Henan International Joint Research Laboratory for Ocular Immunology and Retinal Injury Repair, Department of Ophthalmology, Henan Province Eye Hospital The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan China
Growth Hormone Receptor Antagonism Extends Lifespan
作者Edward O. List; Darlene E. Berryman; Grace S. Lach; Delaney F. Minto; Keeley Weese; John J. Kopchick
作者单位1. Institute of Molecular Medicine and Aging, Heritage College of Osteopathic Medicine Ohio University Athens Ohio USA; 2. The Department of Biomedical Sciences, Heritage College of Osteopathic Medicine Ohio University Athens Ohio USA
Insights Into the Interplay Between the Senescent Cells and Immune Cells
作者Martin Jaros; Marco Schmidt; Lavinia Neubert; Jan‐Christopher Kamp; Sibylle von Vietinghoff; Jan Hinrich Bräsen; Roland Schmitt; Anette Melk
作者单位1. Department of Pediatric Kidney, Liver, Metabolic Diseases and Neuropediatrics Hannover Medical School Germany; 2. Hannover Biomedical Research School Hannover Medical School Hannover Germany; 3. Interdisciplinary Transplantation, Children's Hospital Hannover Medical School Hannover Germany; 4. Institute for Pathology, Hannover Medical School Hannover Germany; 5. Biomedical Research in Endstage and Obstructive Lung Disease Hannover German Center for Lung Research Hannover Germany; 6. Department of Respiratory Medicine Hannover Medical School Hannover Germany; 7. Nephrology Section, Medical Clinic 1 University Hospital Bonn Bonn Germany; 8. Nephropathology Unit, Institute for Pathology Hannover Medical School Hannover Germany; 9. Department of Nephrology Hannover Medical School Hannover Germany; 10. Klinik für Innere Medizin IV mit den Schwerpunkten Nieren‐ Und Hochdruckkrankheiten University Medical Center Schleswig‐Holstein Kiel Germany
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