医学
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Statistical Methodology Groups in the Pharmaceutical Industry #
作者Jenny Devenport; Tobias Mielke; Mouna Akacha; Kaspar Rufibach; Alex Ocampo; Vivian Lanius; Marc Vandemeulebroecke; Philip Hougaard; Pierre Collin; David Wright; Jurgen Hummel; Cornelia Ursula Kunz; Mike Krams
作者单位1. Hoffmann-La Roche AG; 2. Johnson and Johnson; 3. Novartis AG; 4. Merck KGaA; 5. UCB Biosciences GmbH; 6. Bayer BCC AG; 7. H. Lundbeck A/S; 8. Bristol Myers Squibb; 9. AstraZeneca UK Limited; 10. Cytel; 11. Boehringer Ingelheim International GmbH; 12. Berry Consultants
An Adaptive Biomarker-Based Umbrella Trial Design Using Bayesian Latent Class Model
作者Jiaying Guo; Mengyi Lu; Yan Han; Leng Han; Yong Zang
作者单位1. Department of Biostatistics and Health Data Sciences, School of Medicine, Indiana University; 2. Eli Lilly and Company; 3. Department of Biostatistics, Nanjing Medical University; 4. Center for Computational Biology and Bioinformatics, School of Medicine, Indiana University
A Bayesian Adaptive Marker-Stratified Design for Phase II Clinical Trials Using Calibrated Spike-and-Slab Priors
作者Mu Shan; Mengyi Lu; Leng Han; Yan Han; Yong Zang
作者单位1. Department of Biostatistics and Health Data Sciences, School of Medicine, Indiana University; 2. Eli Lilly and Company; 3. Department of Biostatistics, School of Public Health, Nanjing Medical University; 4. Center for Computational Biology and Bioinformatics, School of Medicine, Indiana University
Statistical Method for Threshold Value Determination of Diagnostic Biomarker in Noisy Data
作者Yichen Jia; Donghui Zhang; Francois Beckers; Scott Gallichan; Elizabeth J. Kelly; Saranya Sridhar
作者单位1. Global Biostatistical Science, Sanofi Pasteur; 2. Global Immunology, Sanofi Pasteur; 3. Global Clinical Development, Sanofi Pasteur
Considerations on Interim Evaluation of OS in Pivotal Oncology Trials
作者Weidong Zhang; Sunhee Ro; Jing Zhao; Xiaoyun Li; Qi Jiang; Linda Sun; Olga Marchenko; Chengxing (Cindy) Lu; Rong Liu; on behalf of the Interim Evaluation of OS Workstream of the Statistical Methods in Oncology Scientific Working Group, Biopharmaceutical Section, American Statistical Association
作者单位1. Sana Biotechnology; 2. Nurix Therapeutics; 3. Merck & Co; 4. BeOne Medicines; 5. Pfizer Inc; 6. Bayer; 7. AstraZeneca Plc; 8. Regeneron Pharmaceuticals Inc
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