Drug Metabolism and Pharmacokinetics

作者Daigo Asano; Kazuyoshi Michiba; Kayoko Masuda; Takashi Ohnuki; Makoto Suzuki; Tetsuya Suzuki; Hideyuki Shiozawa; Tsuyoshi Shinozuka; Toshio Takatsu; Daisuke Nakai

作者单位Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan; Modality Research Laboratories I, Daiichi Sankyo Co., Ltd., Tokyo, Japan; Modality Research Laboratories II, Daiichi Sankyo Co., Ltd., Tokyo, Japan; Discovery Science and Technology Department, Daiichi Sankyo RD Novare Co., Ltd., Tokyo, Japan; Analytical & Quality Evaluation Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan; Corporate Planning Department, Daiichi Sankyo Co., Ltd., Tokyo, Japan; Center for Pharmaceutical and Biomedical Analysis, Daiichi Sankyo RD Novare Co., Ltd., Tokyo, Japan

作者Jo Terauchi; Taisei Kawamura; Jongho Park; Kiyomi Saito; Masataka Tajima; Hitoshi Sato; Beomjoon Kim; Erika Sugiyama

作者单位Department of Pharmacokinetics and Pharmacodynamics, Graduate School of Pharmacy, Showa Medical University, Tokyo, Japan, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo, 142-8555, Japan; Department of Precision Engineering, School of Engineering, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-8656, Japan; Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8505, Japan; Innovation Center for Cannabinoid Research, Faculty of Pharmacy, Mahidol University, Bangkok, 10400, Thailand

作者Yuchen Sun; Kosuke Saito; Shin-ichiro Nitta; Ryoya Goda; Yuki Kishino; Hisashi Fujita; Masaaki Kakehi; Yoshiharu Hayashi; Satoshi Ito; Tomomi Ishida; Kiyomi Kikuchi; Kazuko Inoue; Kazutaka Shimbo; Takeru Yamaguchi; Fumihiro Jinno; Kaori Murakoshi; Chie Murata; Kentaro Takahara; Mitsuhiko Kawabata; Ruri Kikura-Hanajiri; Yoshiro Saito

作者单位Division of Medicinal Safety Science, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki City, Kanagawa, 210-9501, Japan; Mediford Corporation, 1-15-10 Shimura, Itabashi-ku, Tokyo, 174-0056, Japan; Future Peak Co., Ltd., 3-48 Imainakamachi, Nakahara-ku, Kawasaki City, Kanagawa, 211-0065, Japan; Daiichi Sankyo Co., Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo, 140-8710, Japan; Takeda Pharmaceutical Co., Ltd., 2-26-1 Muraokahigashi, Fujisawa City, Kanagawa, 251-8555, Japan; CMIC Pharma Science Co., Ltd., 17-18 Nakahatacho, Nishiwaki City, Hyogo, 677-0032, Japan; Sekisui Medical Co., Ltd., 2117 Muramatsu, Tokai-mura naka-gun, Ibaraki, 319-1182, Japan; Eisai Co., Ltd., 5-1-3 Tokodai, Tsukuba, Ibaraki, 300-2635, Japan; Ajinomoto Co., Inc., 1-1 Suzuki-cho, Kawasaki-ku, Kawasaki City, Kanagawa, 210-8681, Japan; Sumika Chemical Analysis Service, Ltd., 3-1-135 Kasugadenaka, Konohana-ku, Osaka City, Osaka, 554-0022, Japan; Axcelead Drug Discovery Partners, Inc., 2-26-1 Muraokahigashi, Fujisawa City, Kanagawa, 251-0012, Japan; Tanabe Pharma Corporation, 2-26-1 Muraokahigashi, Fujisawa City, Kanagawa, 251-8555, Japan; Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai, Shimamotocho, Mishima-gun, Osaka, 618-8585, Japan; Thermo Fisher Scientific K.K., 3-9 Moriyacho, Kanagawa-ku, Yokohama City, Kanagawa, 221-0022, Japan; Shin Nippon Biomedical Laboratories Ltd., 16-1 Minamiakasaka, Kainan-city, Wakayama, 642-0017, Japan; National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki City, Kanagawa, 210-9501, Japan

作者Paulina Page; Dallas Bednarczyk

作者单位Pharmacokinetic Sciences, Novartis Institutes of BioMedical Science, Cambridge, MA, USA

作者Satoshi Nakayama; Nao Torimoto; Toshiyuki Kudo; Kiyomi Ito

作者单位DMPK Research Laboratories, Research Division, Tanabe Pharma Corporation, 1000, Kamoshida-cho Aoba-ku, Yokohama-shi, Kanagawa, 227-0033, Japan; Research Institute of Pharmaceutical Sciences, Musashino University, 1-1-20 Shinmachi, Nishitokyo-shi, Tokyo, 202-8585, Japan

作者Lloyd Wei Tat Tang

作者单位Pharmacokinetics, Dynamics, and Metabolism, Pfizer Inc., Groton, CT, USA

作者Yuka Yaguchi; Kazunari Sasaki; Mai Inagaki; Tetsuya Terasaki; Masanori Tachikawa

作者单位Graduate School of Pharmaceutical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, 770-8505, Japan; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, 980-8578, Japan; Graduate School of Biomedical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, 770-8505, Japan; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, 70210, Finland; Institute of Photonics and Human Health Frontier, Tokushima University, 2-24, Shinkura-cho, Tokushima, 770-8501, Japan

作者Minami Shibata; Ayato Mizuno; Tomoki Nakayoshi; Akifumi Oda; Masaya Nakajima; Masanobu Uchiyama; Masahiro Hiratsuka; Yoshihiro Yamanishi; Kouichi Yoshinari

作者单位Laboratory of Molecular Toxicology, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, Shizuoka, Japan; Laboratory of Biophysical Chemistry, Graduate School of Pharmacy, Meijo University, Nagoya, Japan; Institute for Advanced Research, Nagoya University, Nagoya, Japan; Advanced Elements Chemistry Laboratory, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan; Laboratory of Pharmacogenomics, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan; Department of Complex Systems Science, Graduate School of Informatics, Nagoya University, Nagoya, Japan; Laboratory of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan

作者Takashi Yoshikado; Yukana Tomoda; Kouki Kasai; Reiki Toda; Satofumi Iida; Koji Chiba

作者单位Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama, Kanagawa, 245-0066, Japan

作者Mizuki Umino; Longjian Geng; Yusuke Ushiroda; Makoto Matsumoto; Hidefumi Mukai; Shigeru Kawakami

作者单位School of Pharmaceutical Sciences, Nagasaki University, 1-14 Bunkyo, Nagasaki-shi, Nagasaki, 852-8521, Japan; Department of Pharmaceutical Informatics, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki-shi, Nagasaki, 852-8588, Japan; Leading Medical Research Core Unit, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki-shi, Nagasaki, 852-8588, Japan